Výsledky vyhledávání - "Rasha E. Afifi"

The Herpes Simplex Virus Latency-Associated Transcript Gene Is Associated with a Broader Repertoire of Virus-Specific Exhausted CD8 + T Cells Retained within the Trigeminal Ganglia of Latently Infected HLA Transgenic Rabbits

Autor: Ruchi Srivastava, Nicolas N. Ong, Anthony B. Nesburn, Lbachir BenMohamed, Sravya Chilukuri, Xavier Dervillez, Arif A. Khan, Rasha E. Afifi, Aziz Alami Chentoufi, Nelson Osorio, Roger Geertsema, Nora Shukr, Yasmin Fazli, Steven L. Wechsler

Publikováno v: Journal of Virology. 90:3913-3928

Persistent pathogens, such as herpes simplex virus 1 (HSV-1), have evolved a variety of immune evasion strategies to avoid being detected and destroyed by the host's immune system. A dynamic cross talk appears to occur between the HSV-1 latency-assoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44932e220ac5cc163b68c9c29d642b3c
https://doi.org/10.1128/jvi.02450-15

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The Herpes Simplex Virus 1 Latency-Associated Transcript Promotes Functional Exhaustion of Virus-Specific CD8 + T Cells in Latently Infected Trigeminal Ganglia: a Novel Immune Evasion Mechanism

Autor: Anthony B. Nesburn, Lbachir BenMohamed, Xianzhi Jiang, Dale Carpenter, David C. Yu, Rasha E. Afifi, Chang Hyun Lim, Nelson Osorio, Aziz Alami Chentoufi, Michael V. Tran, Chinhui Hsiang, Steven L. Wechsler, Elizabeth Kritzer, Gargi Dasgupta

Publikováno v: Journal of Virology. 85:9127-9138

Following ocular herpes simplex virus 1 (HSV-1) infection of C57BL/6 mice, HSV-specific (HSV-gB 498–505 tetramer + ) CD8 + T cells are induced, selectively retained in latently infected trigeminal ganglia (TG), and appear to decrease HSV-1 reactiva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::240c036ad11bc4be313807344996aee2
https://doi.org/10.1128/jvi.00587-11

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Protective Immunity to Genital Herpes Simplex Virus Type 1 and Type 2 Provided by Self-Adjuvanting Lipopeptides That Drive Dendritic Cell Maturation and Elicit a Polarized Th1 Immune Response

Autor: Lbachir BenMohamed, Rasha E. Afifi, Xiuli Zhang, Ilham Bettahi

Publikováno v: Viral Immunology. 19:220-236

Genital herpes simplex virus type 1 and type 2 (HSV-1 and HSV-2) infections are a significant health problem worldwide. While it is believed that CD4+ Th1 cells are among the effectors to herpes immunity, developing an epitope-based clinical vaccine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da9b565798e475165b422e7b8a40a2d
https://doi.org/10.1089/vim.2006.19.220

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Akademický článek

Protective Immunity to Genital Herpes Simplex Virus Type 1and Type 2 Provided by Self-Adjuvanting Lipopeptides ThatDrive Dendritic Cell Maturation and Elicit a Polarized Th1Immune Response.

Autor: Ilham Bettahi, Xiuli Zhang, Rasha E. Afifi, Lbachir Benmohamed

Publikováno v: Viral Immunology; Summer2006, Vol. 19 Issue 2, p220-236, 17p

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