Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Rasesh Kapadia"'
Autor:
Katie Rubitschung, Amber Sherwood, Rasesh Kapadia, Yin Xi, Asghar Hajibeigi, Katya B Rubinow, Joseph E Zerwekh, Orhan K Öz
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0296390 (2024)
Estradiol is an important regulator of bone accumulation and maintenance. Circulating estrogens are primarily produced by the gonads. Aromatase, the enzyme responsible for the conversion of androgens to estrogen, is expressed by bone marrow cells (BM
Externí odkaz:
https://doaj.org/article/efec4e92327f450db54d0cee9fa0d877
Autor:
Matthew D. Silva, Anneli Savinainen, Rasesh Kapadia, Jason Ruan, Elizabeth Siebert, Nicole Avitahl, Rebecca Mosher, Karen Anderson, Bruce Jaffee, Lisa Schopf, Sudeep Chandra
Publikováno v:
Molecular Imaging, Vol 3 (2004)
Micro-computed tomographic (micro-CT) imaging provides a unique opportunity to capture 3-D architectural information in bone samples. In this study of pathological joint changes in a rat model of adjuvant-induced arthritis (AA), quantitative analysis
Externí odkaz:
https://doaj.org/article/e74852415f1541ed9754ffd3ac44b8c3
Autor:
Barbara A. Swift, Maxine Gowen, Rasesh Kapadia, Michael W. Lark, George B. Stroup, Alison M. Badger, Joshua M. Levin, Simon M. Blake, William H. Miller, S.J. Hoffman, Susanta K. Sarkar
Publikováno v:
Arthritis & Rheumatism. 44:128-137
Objective To evaluate the effects of SB 273005, a potent, orally active nonpeptide antagonist of the integrin αvβ3 vitronectin receptor, on joint integrity in rats with adjuvant-induced arthritis (AIA). Methods Male Lewis rats with AIA were orally
Autor:
Edward F. Webb, Alison M. Badger, Simon M. Blake, S.J. Hoffman, Jerry L. Adams, Jeffrey C. Boehm, David J. Rieman, Maxine Gowen, Barbara A. Swift, Don E. Griswold, Rasesh Kapadia, John C. Lee, George B. Stroup
Publikováno v:
Arthritis & Rheumatism. 43:175-183
Objective To evaluate the effects of SB 242235, a potent and selective inhibitor of p38 mitogen-activated protein (MAP) kinase, on joint integrity in rats with adjuvant-induced arthritis (AIA). Methods Male Lewis rats with AIA were orally treated eit
Autor:
Bruno Koller, Alison M. Badger, Rasesh Kapadia, Michael W. Lark, Robert W. Coatney, R.A. Dodds, George B. Stroup, Joshua M. Levin, Maxine Gowen, Xiaguong Liang
Publikováno v:
Technology and Health Care. 6:361-372
There is a tremendous unmet therapeutic need for the treatment of osteoporosis and osteoarthritis. The ovariectomized rat and the guinea pig are widely used animal models for the evaluation of new therapeutics for osteoporosis and osteoarthritis, res
Autor:
Scott Wadsworth, Jessica A. Cottrell, J. Patrick O'Connor, Deborah Schachter, Rama Gundlapalli, Rasesh Kapadia, Francis M. Vales
Publikováno v:
Journal of Biomedicine and Biotechnology
Journal of Biomedicine and Biotechnology, Vol 2010 (2010)
Journal of Biomedicine and Biotechnology, Vol 2010 (2010)
The long-term success of arthroplastic joints is dependent on the stabilization of the implant within the skeletal site. Movement of the arthroplastic implant within the bone can stimulate osteolysis, and therefore methods which promote rigid fixatio
Autor:
William H. Miller, David J. Rieman, Ian E. James, Rasesh Kapadia, Xiaoguang Liang, R.A. Dodds, Kevin L. Salyers, Beata Lechowska, George B. Stroup, Shing Mei Hwang, Maxine Gowen, William F. Huffman, Sandra J. Hoffman, Brian R. Smith, Michael W. Lark, Keith W. Ward
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 16(2)
An orally active, nonpeptide Arg-Gly-Asp (RGD) mimetic alpha(v)beta3 antagonist, (S)-3-Oxo-8-[2-[6-(methylamino)-pyridin-2-yl]-1-ethoxy]-2-(2,2,2-trifluoroethyl)-2,3,4,5-tetrahydro-1H-2-benzazepine-4-acetic acid (compound 1), has been generated, whic
Autor:
Rasesh Kapadia, Paul J. Hertzog, Ivan Bertoncello, F. Drake, Maxine Gowen, Francesca Lazner, R.A. Dodds, Silva Zavarselk, Michael Tavaria, Christine Debouck, Irene Tellis, Ismail Kola, John A. Feild
Publikováno v:
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 14(10)
Cathepsin K is a cysteine protease expressed predominantly in osteoclasts. Activated cathepsin K cleaves key bone matrix proteins and is believed to play an important role in degrading the organic phase of bone during bone resorption. Mutations in th
Autor:
Rasesh Kapadia
Publikováno v:
The Journal of the Acoustical Society of America. 127:2006-2006
Developments in hardware and software capabilities, along with a significant increase in access to equipment and awareness of the methods, over the last 10 years have enabled micro‐computed tomography (CT) technology to establish itself as one of t