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Akademický článek

The potential role of omentin-1 in obesity-related metabolic dysfunction-associated steatotic liver disease: evidence from translational studies

Autor: Noel Salvoza, Pablo Giraudi, Silvia Gazzin, Deborah Bonazza, Silvia Palmisano, Nicolò de Manzini, Fabrizio Zanconati, Alan Raseni, Francesca Sirianni, Claudio Tiribelli, Natalia Rosso

Publikováno v: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-14 (2023)

Abstract Background Obesity, characterized by visceral adipose tissue (VAT) expansion, is closely associated with metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH). Recent res

Externí odkaz: https://doaj.org/article/bbc4da373f8242e3aafdaab5a68e28d9

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Akademický článek

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Akademický článek

An Animal Model for the Juvenile Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis.

Autor: Veronica Marin, Natalia Rosso, Matteo Dal Ben, Alan Raseni, Manuela Boschelle, Cristina Degrassi, Ivana Nemeckova, Petr Nachtigal, Claudio Avellini, Claudio Tiribelli, Silvia Gazzin

Publikováno v: PLoS ONE, Vol 11, Iss 7, p e0158817 (2016)

Non Alcoholic Fatty Liver Disease (NAFLD) and Non-Alcoholic Steatohepatitis (NASH) are the hepatic manifestations of the metabolic syndrome; worrisome is the booming increase in pediatric age. To recreate the full spectrum of juvenile liver pathology

Externí odkaz: https://doaj.org/article/8877189aed67467aafe2678a3dc7438d

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Akademický článek

Effects of Oral Administration of Silymarin in a Juvenile Murine Model of Non-alcoholic Steatohepatitis

Autor: Veronica Marin, Silvia Gazzin, Sabrina E. Gambaro, Matteo Dal Ben, Sonia Calligaris, Monica Anese, Alan Raseni, Claudio Avellini, Pablo J. Giraudi, Claudio Tiribelli, Natalia Rosso

Publikováno v: Nutrients, Vol 9, Iss 9, p 1006 (2017)

The increasing prevalence of non-alcoholic fatty liver disease (NAFLD) in adolescents is challenging the global care system. No therapeutic strategies have been defined so far, and changes in the lifestyle remain the only alternative. In this study,

Externí odkaz: https://doaj.org/article/e0bbcbbc34774cc59aa17227334ce1c5

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Activation of hepatic stem cells compartment during hepatocarcinogenesis in a HBsAg HBV-transgenic mouse model

Autor: Beatrice Anfuso, Claudio Tiribelli, Claudio Avellini, Korri Elvanita El-Khobar, Oriano Radillo, Alan Raseni, Susan I. Ie, Caecilia H. C. Sukowati

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports

Chronic infection of Hepatitis B Virus (HBV) is one of the highest risk factors of hepatocellular carcinoma (HCC). The accumulation of HBV surface antigen (HBsAg) into hepatocytes induces inflammation and oxidative stress, impairing their replicative

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c6eda3f2197e3861ec1350ca7eaff8
http://link.springer.com/article/10.1038/s41598-018-31406-5

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Akademický článek

Modulation of Mrp1 (ABCc1) and Pgp (ABCb1) by bilirubin at the blood-CSF and blood-brain barriers in the Gunn rat.

Autor: Silvia Gazzin, Andrea Lorena Berengeno, Nathalie Strazielle, Francesco Fazzari, Alan Raseni, J Donald Ostrow, Richard Wennberg, Jean-François Ghersi-Egea, Claudio Tiribelli

Publikováno v: PLoS ONE, Vol 6, Iss 1, p e16165 (2011)

Accumulation of unconjugated bilirubin (UCB) in the brain causes bilirubin encephalopathy. Pgp (ABCb1) and Mrp1 (ABCc1), highly expressed in the blood-brain barrier (BBB) and blood-cerebrospinal fluid barrier (BCSFB) respectively, may modulate the ac

Externí odkaz: https://doaj.org/article/95b2c903613e41fd8be95c7ebc6388ee

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Hyaluronic acid inhibition by 4-methylumbelliferone reduces the expression of cancer stem cells markers during hepatocarcinogenesis

Autor: Esteban Fiore, Claudio Tiribelli, Caecilia H. C. Sukowati, Fulvia Vascotto, Claudio Avellini, Beatrice Anfuso, Alan Raseni, Guillermo Mazzolini, Susan I. Ie

Publikováno v: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Hyaluronic acid (HA) is a glycosaminoglycan of extracellular matrix related to cell surface which interacts with various cell types. To understand the role of HA during hepatocarcinogenesis, we assessed the effect of the inhibition of HA deposition a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e83a540cb3ea40b5385182419122ae18
https://doi.org/10.1038/s41598-019-40436-6

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Effects of oral administration of silymarin in a juvenile murine model of non-alcoholic steatohepatitis

Autor: Claudio Avellini, Silvia Gazzin, Natalia Rosso, Matteo Dal Ben, Claudio Tiribelli, Pablo J. Giraudi, Sonia Calligaris, Monica Anese, Alan Raseni, Sabrina Eliana Gambaro, V. Marin

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Nutrients
Nutrients; Volume 9; Issue 9; Pages: 1006
Nutrients, Vol 9, Iss 9, p 1006 (2017)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f5ad12f3b168cc100e768d73a42fb4
https://www.mdpi.com/2072-6643/9/9/1006

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