Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Rasem, Fattah"'
Publikováno v:
mBio, Vol 15, Iss 12 (2024)
ABSTRACT Bacillus anthracis causes anthrax through a combination of bacterial infection and toxemia. As a major virulence factor of B. anthracis, anthrax lethal toxin (LT) is a zinc-dependent metalloproteinase, exerting its cytotoxicity through prote
Externí odkaz:
https://doaj.org/article/705cd8d2d47949748c4c4684ef5f2571
Autor:
Elena Wei, Charles Bou-Nader, Megan L. Perry, Rasem Fattah, Jinwei Zhang, Stephen H. Leppla, Ankur Bothra
Publikováno v:
Bioconjugate Chemistry. 34:834-844
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ffaa511736a3390db98e1a57e19910e
https://doi.org/10.1021/acs.bioconjchem.2c00609
https://doi.org/10.1021/acs.bioconjchem.2c00609
Autor:
Andrei P Pomerantsev, Rita M McCall, Margaret Chahoud, Nathan K Hepler, Rasem Fattah, Stephen H Leppla
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183346 (2017)
Tyrosine site-specific recombinases (T-SSR) are polynucleotidyltransferases that catalyze cutting and joining reactions between short specific DNA sequences. We developed three systems for performing genetic modifications in Bacillus anthracis that u
Externí odkaz:
https://doaj.org/article/f0003f0ce2cf4c319aa26b926eb8254d
Autor:
Inka Sastalla, Rasem Fattah, Nicole Coppage, Poulomi Nandy, Devorah Crown, Andrei P Pomerantsev, Stephen H Leppla
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76955 (2013)
Bacillus cereus is a spore-forming, Gram-positive bacterium commonly associated with outbreaks of food poisoning. It is also known as an opportunistic pathogen causing clinical infections such as bacteremia, meningitis, pneumonia, and gas gangrene-li
Externí odkaz:
https://doaj.org/article/37e4c17b5ed24b6581afd786879cc243
Autor:
Jonathan L Levinsohn, Zachary L Newman, Kristina A Hellmich, Rasem Fattah, Matthew A Getz, Shihui Liu, Inka Sastalla, Stephen H Leppla, Mahtab Moayeri
Publikováno v:
PLoS Pathogens, Vol 8, Iss 3, p e1002638 (2012)
NOD-like receptor (NLR) proteins (Nlrps) are cytosolic sensors responsible for detection of pathogen and danger-associated molecular patterns through unknown mechanisms. Their activation in response to a wide range of intracellular danger signals lea
Externí odkaz:
https://doaj.org/article/92d7ede8a47440739881cd70d2f2c59a
Autor:
Kristina A Hellmich, Jonathan L Levinsohn, Rasem Fattah, Zachary L Newman, Nolan Maier, Inka Sastalla, Shihui Liu, Stephen H Leppla, Mahtab Moayeri
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49741 (2012)
Anthrax lethal factor (LF) is the protease component of anthrax lethal toxin (LT). LT induces pyroptosis in macrophages of certain inbred mouse and rat strains, while macrophages from other inbred strains are resistant to the toxin. In rats, the sens
Externí odkaz:
https://doaj.org/article/7769dd7468d341399e76a5d594b64fd8
Autor:
Rita M, McCall, Mary E, Sievers, Rasem, Fattah, Rodolfo, Ghirlando, Andrei P, Pomerantsev, Stephen H, Leppla
Publikováno v:
J Bacteriol
Anthrax toxin activator (AtxA) is the master virulence gene regulator of Bacillus anthracis. It regulates genes on the chromosome as well as the pXO1 and pXO2 plasmids. It is not clear how AtxA regulates these genes, and direct binding of AtxA to its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a58cd898f437e4b0b148b343a8bc7c02
https://pubmed.ncbi.nlm.nih.gov/31570528
https://pubmed.ncbi.nlm.nih.gov/31570528
Autor:
Rasem Fattah, Peter Wei-Jen Fan, Charles A. Panetta, Dezhi Sha, Charles L. Hussey, Zhuoli He, Lyle D. Wescott, Joe C. Greever
Publikováno v:
The Journal of organic chemistry. 64(8)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::538a0e6c706f3eeb1b9bec250b2569f2
https://pubmed.ncbi.nlm.nih.gov/11674367
https://pubmed.ncbi.nlm.nih.gov/11674367
Autor:
Vladimir A. Karginov, Holger Barth, Sergey M. Bezrukov, Xian Liu, Stephen H. Leppla, Alexander N. Wein, Michel R. Popoff, Ekaterina M. Nestorovich
Publikováno v:
Biophysical Journal
Biophysical Journal, Biophysical Society, 2012, 103 (6), pp.1208-1217. ⟨10.1016/j.bpj.2012.07.050⟩
Biophysical Journal, 2012, 103 (6), pp.1208-1217. ⟨10.1016/j.bpj.2012.07.050⟩
Biophysical Journal, Biophysical Society, 2012, 103 (6), pp.1208-1217. ⟨10.1016/j.bpj.2012.07.050⟩
Biophysical Journal, 2012, 103 (6), pp.1208-1217. ⟨10.1016/j.bpj.2012.07.050⟩
International audience; Cationic β-cyclodextrin derivatives were recently introduced as highly effective, potentially universal blockers of three binary bacterial toxins: anthrax toxin of Bacillus anthracis, C2 toxin of Clostridium botulinum, and io
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d062d9d7dac38205af69a27af8ea4ee2