Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Rasel A Al-Amin"'
Autor:
Peter Lönn, Rasel A. Al-Amin, Ehsan Manouchehri Doulabi, Johan Heldin, Radiosa Gallini, Johan Björkesten, Johan Oelrich, Masood Kamali-Moghaddam, Ulf Landegren
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
To improve our ability to monitor cellular responses to e.g. cytokines or drugs, Lönn et al have developed a semi-automated system for large-scale in situ proximity ligation assays (isPLA) in HaCAT keratinocyte cells. Their approach expands the scop
Externí odkaz:
https://doaj.org/article/e5ecdbaa06634e1d97b74de9458d189e
Publikováno v:
Analytical Chemistry
The ability to monitor target engagement in cellular contexts is a key for successful drug discovery and also valuable in clinical routine. A cellular thermal shift assay (CETSA) provides realistic information about drug binding in cells and tissues,
Autor:
Rasel A. Al-Amin, Phathutshedzo M. Muthelo, Eldar Abdurakhmanov, Cécile Vincke, Shahnaz P. Amin, Serge Muyldermans, U. Helena Danielson, Ulf Landegren
Publikováno v:
Analytical chemistry. 94(28)
High-quality affinity probes are critical for sensitive and specific protein detection, in particular for detection of protein biomarkers in the early phases of disease development. Proximity extension assays (PEAs) have been used for high-throughput
Autor:
Masood Kamali-Moghaddam, Rasel A. Al-Amin, Ehsan Manouchehri Doulabi, Johan Björkesten, Peter Lönn, Johan Heldin, Radiosa Gallini, Ulf Landegren, Johan Oelrich
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
Communications Biology
Communications Biology
Protein interactions and posttranslational modifications orchestrate cellular responses to e.g. cytokines and drugs, but it has been difficult to monitor these dynamic events in high-throughput. Here, we describe a semi-automated system for large-sca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d8fa2e1a506a5e0a72143f491041a88
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-459770
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-459770
Publikováno v:
New biotechnology. 45
Plasma proteome analyses of the future promise invaluable insights into states of health, not only by measuring proteins whose role it is to ensure blood homeostasis, but increasingly also as a window into the health of practically any tissue in the