Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Rare disease assumption"'
Publikováno v:
Journal of Epidemiology, Vol 33, Iss 10, Pp 508-513 (2023)
Background: In case-cohort studies with binary outcomes, ordinary logistic regression analyses have been widely used because of their computational simplicity. However, the resultant odds ratio estimates cannot be interpreted as relative risk measure
Externí odkaz:
https://doaj.org/article/1bdb8df1d4b8424c9e4f59bab3876813
Autor:
Virginia L. Ma, Shili Lin
Publikováno v:
Mathematical Biosciences and Engineering, Vol 17, Iss 1, Pp 73-91 (2020)
Many statistical methods for analyzing genetic data, such as those used in genome-wide association studies, assume Hardy-Weinberg Equilibrium (HWE). Therefore, to use such methods, one must check whether the HWE assumption is valid. For a case-contro
Externí odkaz:
https://doaj.org/article/9446742c6cd1415ab327dee617545a23
Akademický článek
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Autor:
Gene Pennello
Publikováno v:
Biostatistics & Epidemiology. 5:149-168
In diagnostic test evaluation, performance goals are often set for classification accuracy measures such as specificity, sensitivity and diagnostic likelihood ratio. For tests that detect rare cond...
Akademický článek
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Publikováno v:
medRxiv
SummarySARS-CoV-2 continues to evolve and the vaccine efficacy against variants is challenging to estimate. It is now common in phase III vaccine trials to provide vaccine to those randomized to placebo once efficacy has been demonstrated, precluding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7338d45a549fb79ed1efdace0e615ea
https://doi.org/10.1101/2021.08.31.21262908
https://doi.org/10.1101/2021.08.31.21262908
Autor:
W. Dana Flanders
Publikováno v:
American Journal of Epidemiology. 189:91-94
The case-control study design has evolved substantially over the past half century. The design has long been recognized as a way to increase efficiency by studying fewer subjects than would be required for a full cohort study. Historically, it was th
A semiparametric efficient estimator in case-control studies for gene–environment independent models
Publikováno v:
Journal of Multivariate Analysis. 173:38-50
Case-controls studies are popular epidemiological designs for detecting gene–environment interactions in the etiology of complex diseases, where the genetic susceptibility and environmental exposures may often be reasonably assumed independent in t
Autor:
Christl A. Donnelly, Scott Leslie O'Neill, Zoe Cutcher, Katherine L. Anders, Peter A. Ryan, Immo Kleinschmidt, Cameron P. Simmons, Nicholas P. Jewell, Neil M. Ferguson, Citra Indriani
Publikováno v:
American Journal of Epidemiology
Cluster-randomized controlled trials are the gold standard for assessing efficacy of community-level interventions, such as vector-control strategies against dengue. We describe a novel cluster-randomized trial methodology with a test-negative design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a4e8c7b3e751cc25a63f98b35228b29
http://hdl.handle.net/10044/1/59322
http://hdl.handle.net/10044/1/59322
Autor:
Heather Whitaker, Ian J. Douglas, C. Paddy Farrington, Yonas Ghebremichael-Weldeselassie, Liam Smeeth
Publikováno v:
Computational Statistics & Data Analysis. 113:64-72
Self-controlled case series methods for events that may be classified as one of several types are described. When the event is non-recurrent, the different types correspond to competing risks. It is shown that, under circumstances that are likely to