Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Raquel Torrens"'
Autor:
Patricia Pérez-Matute, Icíar P. López, María Íñiguez, Emma Recio-Fernández, Raquel Torrens, Sergio Piñeiro-Hermida, Elvira Alfaro-Arnedo, Luong Chau, Christina Walz, Andreas Hoeflich, José A. Oteo, José G. Pichel
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
ObjectiveWe aimed to investigate the short and long-term metabolic consequences of IGF1R systemic gene deficiency in mice.MethodsUBC-CreERT2, Igf1rfl/fl mutant mice were used to suppress IGF1R signaling in adult tissues by inducing postnatal generali
Externí odkaz:
https://doaj.org/article/d487c97cd50643339ffa6225129c7e2c
Autor:
Sergio Piñeiro-Hermida, Icíar P. López, Elvira Alfaro-Arnedo, Raquel Torrens, María Iñiguez, Lydia Alvarez-Erviti, Carlos Ruíz-Martínez, José G. Pichel
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract IGF1R (Insulin-like Growth Factor 1 Receptor) is a tyrosine kinase with pleiotropic cellular functions. IGF activity maintains human lung homeostasis and is implicated in pulmonary diseases such as cancer, ARDS, COPD, asthma and fibrosis. He
Externí odkaz:
https://doaj.org/article/3b2793cee94e4995ba43123296da8895
Autor:
Sergio Piñeiro-Hermida, Elvira Alfaro-Arnedo, Joshua A Gregory, Raquel Torrens, Carlos Ruíz-Martínez, Mikael Adner, Icíar P López, José G Pichel
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0190159 (2017)
Asthma is a chronic inflammatory disease characterized by bronchial hyperresponsiveness, mucus overproduction and airway remodeling. Notably, we have recently demonstrated that insulin-like growth factor 1 receptor (IGF1R) deficiency in mice attenuat
Externí odkaz:
https://doaj.org/article/af15676d209e4d1a9ee47fddd1eea8b3
Autor:
Icíar P López, Sergio Piñeiro-Hermida, Rosete S Pais, Raquel Torrens, Andreas Hoeflich, José G Pichel
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166388 (2016)
Regeneration of lung epithelium is vital for maintaining airway function and integrity. An imbalance between epithelial damage and repair is at the basis of numerous chronic lung diseases such as asthma, COPD, pulmonary fibrosis and lung cancer. IGF
Externí odkaz:
https://doaj.org/article/22e669fc41e144a2b4ccddc5cb7ad375
Autor:
Icíar P. López, Lydia Alvarez-Erviti, Sergio Piñeiro-Hermida, María Íñiguez, Raquel Torrens, José G. Pichel, Elvira Alfaro-Arnedo, Carlos Ruíz-Martínez
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
IGF1R (Insulin-like Growth Factor 1 Receptor) is a tyrosine kinase with pleiotropic cellular functions. IGF activity maintains human lung homeostasis and is implicated in pulmonary diseases such as cancer, ARDS, COPD, asthma and fibrosis. Here we rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae790d7ac417051626d31de41d9c3480
https://doaj.org/article/3b2793cee94e4995ba43123296da8895
https://doaj.org/article/3b2793cee94e4995ba43123296da8895
Autor:
Icíar P. López, Raquel Torrens, Joshua A. Gregory, José G. Pichel, Carlos Ruíz-Martínez, Sergio Piñeiro-Hermida, Mikael Adner
Publikováno v:
Allergy. 72:1317-1326
Background Asthma is a common chronic lung disease characterized by airflow obstruction, airway hyperresponsiveness (AHR) and inflammation. IGFs have been reported to play a role in asthma but little is known about how the Insulin-like Growth Factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5960864fb4cdc4e198643f007b9760a4
https://doi.org/10.1111/all.13142
https://doi.org/10.1111/all.13142
Autor:
Rosete Sofia Pais, Raquel Torrens, Sergio Piñeiro-Hermida, Icíar P. López, José G. Pichel, Lourdes Rodriguez-de la Rosa, Julio Contreras, Isabel Varela-Nieto
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
et al.
Insulin-like growth factor type 1 receptor (IGF1R) is a ubiquitously expressed tyrosine kinase that regulates cell proliferation, differentiation and survival. It controls body growth and organ homeostasis, but with specific functions dep
Insulin-like growth factor type 1 receptor (IGF1R) is a ubiquitously expressed tyrosine kinase that regulates cell proliferation, differentiation and survival. It controls body growth and organ homeostasis, but with specific functions dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ffe4629cbef2e50ec4cb6c298af273
https://doi.org/10.1007/s11248-014-9837-5
https://doi.org/10.1007/s11248-014-9837-5
Autor:
Sergio Piñeiro-Hermida, José G. Pichel, Icíar P. López, Rosete Sofia Pais, Raquel Torrens, Andreas Hoeflich
Publikováno v:
PLoS ONE
PLOS ONE, 11(11):e0166388
PLoS ONE, Vol 11, Iss 11, p e0166388 (2016)
PLOS ONE, 11(11):e0166388
PLoS ONE, Vol 11, Iss 11, p e0166388 (2016)
Regeneration of lung epithelium is vital for maintaining airway function and integrity. An imbalance between epithelial damage and repair is at the basis of numerous chronic lung diseases such as asthma, COPD, pulmonary fibrosis and lung cancer. IGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a08fa6445e82c5d8fdff431658285e61
http://europepmc.org/articles/PMC5115747
http://europepmc.org/articles/PMC5115747
Autor:
José A. Oteo, Emma Recio-Fernández, José Ramón Blanco, Raquel Torrens, María Íñiguez, José G. Pichel, Patricia Pérez-Matute, Laura Pérez-Martínez
Publikováno v:
Antiviral therapy. 22(2)
Background Any strategy designed to decrease the macrophage content in adipose tissue (AT) is of great value as a way to decrease inflammation in this fat depot and also as a way to prevent or treat obesity and associated disorders. Maraviroc (MVC),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a5eed3c3e677ee98486dc24a898003
https://pubmed.ncbi.nlm.nih.gov/27725337
https://pubmed.ncbi.nlm.nih.gov/27725337