Paternal DDT exposure induces sex-specific programming of fetal growth, placenta development and offspring’s health phenotypes in a mouse model

Autor: Elaine Chen, Raquel Santana da Cruz, Aallya Nascimento, Meghali Joshi, Duane Gischewski Pereira, Odalys Dominguez, Gabriela Fernandes, Megan Smith, Sara P. C. Paiva, Sonia de Assis

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)

Abstract Mounting evidence suggests that environmentally induced epigenetic inheritance occurs in mammals and that traits in the progeny can be shaped by parental environmental experiences. Epidemiological studies link parental exposure to environmen

Externí odkaz: https://doaj.org/article/adef8076926e407999ec2fbd851ba888

Diet and Transgenerational Epigenetic Inheritance of Breast Cancer: The Role of the Paternal Germline

Autor: Raquel Santana da Cruz, Elaine Chen, Megan Smith, Jaedus Bates, Sonia de Assis

Publikováno v: Frontiers in Nutrition, Vol 7 (2020)

The past decade has made evident that in addition to passing their genetic material at conception, parents also transmit a molecular memory of past environmental experiences, including nutritional status, to their progeny through epigenetic mechanism

Externí odkaz: https://doaj.org/article/a55fa5d936e644aab3b3c4dcfc012d9d

β-ionone inhibits nonalcoholic fatty liver disease and its association with hepatocarcinogenesis in male Wistar rats

Autor: Inar Alves de Castro, Mayara Lilian Paulino Miranda, Fábia de Oliveira Andrade, Raquel Santana da Cruz, Renato Heidor, Luis Fernando Barbisan, Maria do Socorro Nogueira, Fernando Salvador Moreno, Kelly Silva Furtado, Eduardo Purgatto

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2019-10-06T16:34:33Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-08-01 Among the primary neoplasias that affect the liver, hepatocellular carcinoma (HCC) is the most frequent and the third leading cause of death

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b19dfb9022fa4886dbd4925dba98fd6b
https://doi.org/10.1016/j.cbi.2019.05.046

Abstract 1429: DDT induces intergenerational epigenetic inheritance of cancer predisposition in a mouse model

Autor: Raquel Santana Da Cruz, Odalys Dominguez, Apsra Nasir, Alexandra K. Gonsiewski, Maria Idalia Cruz, Lu Jin, Matthew McCoy, Sonia de Assis

Publikováno v: Cancer Research. 82:1429-1429

DNA sequence accounts for the majority of disease heritability, including cancer. Yet, not all familial cancer cases can be explained by genetic factors. There is mounting evidence that environmentally-induced epigenetic inheritance occurs and that t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::64e5a37e6276ccb25fe605fc6ea4be01
https://doi.org/10.1158/1538-7445.am2022-1429

Parental obesity programs pancreatic cancer development in offspring

Autor: Aseel Al-Yawar, Sonia de Assis, M. Idalia Cruz, Ana Cristina P Curi, Ali Baird, Raquel Santana da Cruz, Johan Clarke, Lu Jin, Bhaskar Kallakury

Publikováno v: Endocr Relat Cancer

Epidemiological studies suggest that timing of obesity onset – and underlying metabolic dysfunction – is important in determining pancreatic cancer rates: early and young adult abdominal overweight/obesity is more strongly associated with this ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a67fed14b623246317ed19e61b9de7e0
https://europepmc.org/articles/PMC6717698/