Evaluation of didactic units on historical thinking and active methods

Autor: Pedro Miralles-Sánchez, Jairo Rodríguez-Medina, Raquel Sánchez-Ibáñez

Publikováno v: Humanities & Social Sciences Communications, Vol 11, Iss 1, Pp 1-11 (2024)

Abstract The purpose of this study is to evaluate the effects of an implementation of eight didactic units on historical thinking and active methods as part of a teacher training programme. All this with four specific objectives that try to find out

Externí odkaz: https://doaj.org/article/56cc4752427446fda36575c355fd47c0

Vitamin D status in female dogs with mammary gland tumors

Autor: Carmen Pineda, Ana I. Raya, Juan Morgaz, Raquel Sánchez‐Céspedes, Yolanda Millán, Escolástico Aguilera‐Tejero, Ignacio López

Publikováno v: Journal of Veterinary Internal Medicine, Vol 38, Iss 4, Pp 2257-2264 (2024)

Abstract Background Little information exists about vitamin D status in bitches with mammary tumors. Objectives To determine whether low plasma vitamin D concentrations are found in bitches with mammary tumors. Animals Eighty‐five client‐owned bi

Externí odkaz: https://doaj.org/article/e6e31da490df4cffa443753717af65f9

Increase in wasteosomes (corpora amylacea) in frontotemporal lobar degeneration with specific detection of tau, TDP-43 and FUS pathology

Autor: Raquel Alsina, Marta Riba, Agnès Pérez-Millan, Sergi Borrego-Écija, Iban Aldecoa, Clara Romera, Mircea Balasa, Anna Antonell, Albert Lladó, Yaroslau Compta, Jaume del Valle, Raquel Sánchez-Valle, Carme Pelegrí, Laura Molina-Porcel, Jordi Vilaplana

Publikováno v: Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-13 (2024)

Abstract Wasteosomes (or corpora amylacea) are polyglucosan bodies that appear in the human brain with aging and in some neurodegenerative diseases, and have been suggested to have a potential role in a nervous system cleaning mechanism. Despite prev

Externí odkaz: https://doaj.org/article/b86c83d11cbe43639df93dc8a849e7ee

Clinical and research application of fluid biomarkers in autosomal dominant Alzheimer's disease and Down syndrome

Autor: María Carmona-Iragui, Antoinette O'Connor, Jorge Llibre-Guerra, Patrick Lao, Nicholas J. Ashton, Juan Fortea, Raquel Sánchez-Valle

Publikováno v: EBioMedicine, Vol 108, Iss , Pp 105327- (2024)

Summary: Autosomal dominant Alzheimer's disease (ADAD) and Down syndrome (DS) constitute genetic forms of Alzheimer's disease (AD). The study of these forms has been crucial in understanding the biomarker changes and disease progression, notably in a

Externí odkaz: https://doaj.org/article/8547582ebab9497f8370b64b43339c2f

A systematic review of progranulin concentrations in biofluids in over 7,000 people—assessing the pathogenicity of GRN mutations and other influencing factors

Autor: Imogen J. Swift, Rosa Rademakers, NiCole Finch, Matt Baker, Roberta Ghidoni, Luisa Benussi, Giuliano Binetti, Giacomina Rossi, Matthis Synofzik, Carlo Wilke, David Mengel, Caroline Graff, Leonel T. Takada, Raquel Sánchez-Valle, Anna Antonell, Daniela Galimberti, Chiara Fenoglio, Maria Serpente, Marina Arcaro, Stefanie Schreiber, Stefan Vielhaber, Philipp Arndt, Isabel Santana, Maria Rosario Almeida, Fermín Moreno, Myriam Barandiaran, Alazne Gabilondo, Johannes Stubert, Estrella Gómez-Tortosa, Pablo Agüero, M. José Sainz, Tomohito Gohda, Maki Murakoshi, Nozomu Kamei, Sarah Kittel-Schneider, Andreas Reif, Johannes Weigl, Jinlong Jian, Chuanju Liu, Ginette Serrero, Thomas Greither, Gerit Theil, Ebba Lohmann, Stefano Gazzina, Silvia Bagnoli, Giovanni Coppola, Amalia Bruni, Mirja Quante, Wieland Kiess, Andreas Hiemisch, Anne Jurkutat, Matthew S. Block, Aaron M. Carlson, Geir Bråthen, Sigrid Botne Sando, Gøril Rolfseng Grøntvedt, Camilla Lauridsen, Amanda Heslegrave, Carolin Heller, Emily Abel, Alba Gómez-Núñez, Roger Puey, Andrea Arighi, Enmanuela Rotondo, Lize C. Jiskoot, Lieke H. H. Meeter, João Durães, Marisa Lima, Miguel Tábuas-Pereira, João Lemos, Bradley Boeve, Ronald C. Petersen, Dennis W. Dickson, Neill R. Graff-Radford, Isabelle LeBer, Leila Sellami, Foudil Lamari, Fabienne Clot, Barbara Borroni, Valentina Cantoni, Jasmine Rivolta, Alberto Lleó, Juan Fortea, Daniel Alcolea, Ignacio Illán-Gala, Lucie Andres-Cerezo, Philip Van Damme, Jordi Clarimon, Petra Steinacker, Emily Feneberg, Markus Otto, Emma L. van der Ende, John C. van Swieten, Harro Seelaar, Henrik Zetterberg, Aitana Sogorb-Esteve, Jonathan D. Rohrer

Publikováno v: Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-13 (2024)

Abstract Background Pathogenic heterozygous mutations in the progranulin gene (GRN) are a key cause of frontotemporal dementia (FTD), leading to significantly reduced biofluid concentrations of the progranulin protein (PGRN). This has led to a number

Externí odkaz: https://doaj.org/article/1d7c751ac55c494a90e49ef788756561