Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Raquel Sá-Leão"'
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-20 (2023)
Abstract Background The microbiota of the upper respiratory tract is increasingly recognized as a gatekeeper of respiratory health. Despite this, the microbiota of healthy adults remains understudied. To address this gap, we investigated the composit
Externí odkaz:
https://doaj.org/article/e0251350f6ee4fbc880bcfd128026c6c
Autor:
A. Cristina Paulo, Raquel Sá-Leão
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Understanding how pneumococci respond to pneumococcal conjugate vaccines (PCVs) is crucial to predict the impact of upcoming higher-valency vaccines. However, stages in pneumococcal community succession following disturbance are poorly under
Externí odkaz:
https://doaj.org/article/bfe50e7dfb3442e39cf4597198c6e056
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Streptococcus pneumoniae causes significant morbidity and mortality among older adults. Detection of pneumococcal carriage is an accepted endpoint in pneumococcal conjugate vaccine studies. However, low sensitivity of culture-based approaches and nas
Externí odkaz:
https://doaj.org/article/0cefbeb174cd4d74b1ca96722ce2f92f
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2022)
Streptococcus pneumoniae is a human pathogen responsible for high morbidity and mortality worldwide. Disease is incidental and is preceded by asymptomatic nasopharyngeal colonization in the form of biofilms. Simultaneous colonization by multiple pneu
Externí odkaz:
https://doaj.org/article/5e10a4e3b51d46da9df1c44b695e39a8
Autor:
Alexandra Sofia Simões, Tiago Touret, Nuno Alexandre Faria, Susana Peres Ladeiro, João Costa, Soraia Bispo, Mónica Serrano, Carlos Palos, Maria Miragaia, Ricardo Bastos Leite, Raquel Sá-Leão
Publikováno v:
Acta Médica Portuguesa, Vol 35, Iss 1 (2022)
Introduction: Healthcare associated infections due to carbapenem-resistant Klebsiella pneumoniae (CRKP) are a major concern in Portuguese hospitals. Whole genome sequencing (WGS) can improve infection control, but this practice is not routinely used
Externí odkaz:
https://doaj.org/article/42f6351211ff4797925ad8469f89b3ea
Autor:
Maria Paula Bajanca-Lavado, Luís Cavaco, Mariana Fernandes, Tiago Touret, Catarina Candeias, Alexandra S. Simões, Raquel Sá-Leão
Publikováno v:
Microorganisms, Vol 10, Iss 10, p 1964 (2022)
Haemophilus influenzae is an important cause of mucosal and invasive infections and a common colonizer of the upper respiratory tract. As there are no recent data on H. influenzae carriage in Portugal, we aimed to characterize carriage samples and in
Externí odkaz:
https://doaj.org/article/f8e3d64f93a74eecb1e92627b726aaef
Autor:
Joshua C D'Aeth, Mark PG van der Linden, Lesley McGee, Herminia de Lencastre, Paul Turner, Jae-Hoon Song, Stephanie W Lo, Rebecca A Gladstone, Raquel Sá-Leão, Kwan Soo Ko, William P Hanage, Robert F Breiman, Bernard Beall, Stephen D Bentley, Nicholas J Croucher, The GPS Consortium
Publikováno v:
eLife, Vol 10 (2021)
Multidrug-resistant Streptococcus pneumoniae emerge through the modification of core genome loci by interspecies homologous recombinations, and acquisition of gene cassettes. Both occurred in the otherwise contrasting histories of the antibiotic-resi
Externí odkaz:
https://doaj.org/article/72ee08bedd544a80947d2d1d6c45f963
Autor:
Sónia T Almeida, A Cristina Paulo, João Babo, João Borralho, Catarina Figueiredo, Bruno Gonçalves, João Lança, Mónica Louro, Hermes Morais, Joana Queiroz, Hermínia de Lencastre, Raquel Sá-Leão
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0253739 (2021)
Methicillin-resistant Staphylococcus aureus (MRSA) has long been known as a major cause of hospital-acquired (HA-MRSA) infections worldwide. For the past twenty years, an increasing number of studies have described its emergence in the community as w
Externí odkaz:
https://doaj.org/article/035f7bd4c2f34bed9dadfe839696fb25
Autor:
Geneviève Garriss, Priyanka Nannapaneni, Alexandra S. Simões, Sarah Browall, Karthik Subramanian, Raquel Sá-Leão, Herman Goossens, Herminia de Lencastre, Birgitta Henriques-Normark
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT Streptococcus pseudopneumoniae is a close relative of the major human pathogen S. pneumoniae. It is increasingly associated with lower-respiratory-tract infections (LRTI) and a high prevalence of antimicrobial resistance (AMR). S. pseudopneu
Externí odkaz:
https://doaj.org/article/0bc1f1ef40f84d038a186ac45502dafb
Autor:
N. Luisa Hiller, Raquel Sá-Leão
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
The Gram positive bacterium Streptococcus pneumoniae (pneumococcus) is a major human pathogen. It is a common colonizer of the human host, and in the nasopharynx, sinus, and middle ear it survives as a biofilm. This mode of growth is optimal for mult
Externí odkaz:
https://doaj.org/article/b6940370e1fd44e4b2d72dae51a3eacf