Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Raquel Rodriguez-Acebes"'
Autor:
Carmen Cuevas, Carlos M. Galmarini, Simon Munt, Juan Fernando Martínez-Leal, Andrés Francesch, José Manuel Molina-Guijarro, Raquel Rodriguez-Acebes, Cristina Mateo, María José Muñoz-Alonso, María José Guillén, Juan Manuel Domínguez, Pablo Avilés
In the search for novel payloads to design new antibody–drug conjugates (ADC), marine compounds represent an interesting opportunity given their unique chemical features. PM050489 is a marine compound that binds β-tubulin at a new site and disrupt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a25a1dab9a8b993ce7913eaf0afa003
https://doi.org/10.1158/1535-7163.c.6537714
https://doi.org/10.1158/1535-7163.c.6537714
Autor:
Carmen Cuevas, Carlos M. Galmarini, Simon Munt, Juan Fernando Martínez-Leal, Andrés Francesch, José Manuel Molina-Guijarro, Raquel Rodriguez-Acebes, Cristina Mateo, María José Muñoz-Alonso, María José Guillén, Juan Manuel Domínguez, Pablo Avilés
Description of synthetic method for PM120160 Supplementary Figure 1. Analysis of MI130004. A: Analytical size exclusion chromatography analysis performed on a Superdex-100 10/300 column running an isocratic method with PBS at 1 mL/min. B: HIC analysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad73df484691af858d6554e941eb9864
https://doi.org/10.1158/1535-7163.22504368.v1
https://doi.org/10.1158/1535-7163.22504368.v1
Autor:
Patricia G. Cruz, Rogelio Fernández, Raquel Rodríguez-Acebes, Marta Martínez-Díez, Gema Santamaría-Núñez, Marta Pérez, Carmen Cuevas
Publikováno v:
Marine Drugs, Vol 22, Iss 8, p 339 (2024)
PM742 (1), a new chemical entity, has been isolated from the sponge Discodermia du Bocage collected in the Pacific Ocean. This compound showed strong in vitro cytotoxicity against several human tumor cell lines as well as a tubulin depolymerization m
Externí odkaz:
https://doaj.org/article/f33b414347b749519ef3de6ab2f82de1
Autor:
Pablo, Avilés, Juan Manuel, Domínguez, María José, Guillén, María José, Muñoz-Alonso, Cristina, Mateo, Raquel, Rodriguez-Acebes, José Manuel, Molina-Guijarro, Andrés, Francesch, Juan Fernando, Martínez-Leal, Simon, Munt, Carlos M, Galmarini, Carmen, Cuevas
Publikováno v:
Molecular cancer therapeutics. 17(4)
In the search for novel payloads to design new antibody-drug conjugates (ADC), marine compounds represent an interesting opportunity given their unique chemical features. PM050489 is a marine compound that binds β-tubulin at a new site and disrupts