Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Raquel Revilla-Sanchez"'
Autor:
Karla Kretschmannova, Paul Davies, Rachel Jurd, Verena Tretter, Raquel Revilla-Sanchez, Max B. Kelz, Stephen J. Moss, Miho Terunuma, Rochelle M. Hines
Publikováno v:
The Journal of Neuroscience. 33:7264-7273
Intravenous anesthetics exert a component of their actions via potentiating inhibitory neurotransmission mediated by γ-aminobutyric type-A receptors (GABAARs). Phasic and tonic inhibition is mediated by distinct populations of GABAARs, with the majo
Publikováno v:
Neuropharmacology. 59:268-275
Amyloid-beta (Abeta) deposition is a defining feature of Alzheimer's disease (AD). The toxicity of Abeta aggregation is thought to contribute to clinical deficits including progressive memory loss and cognitive dysfunction. Therefore, Abeta peptide h
Autor:
Cédrick Florian, Guido Michels, Stephen J. Moss, Rachel Jurd, Catriona M. Houston, Robbert Havekes, Ted Abel, Verena Tretter, Mansi Vithlani, Miho Terunuma, Raquel Revilla-Sanchez, Andrés Couve, Trevor G. Smart, Werner Sieghart, Nicholas J. Brandon
Publikováno v:
Proceedings of the National Academy of Sciences. 106:20039-20044
Fast synaptic inhibition in the brain is largely mediated by γ-aminobutyric acid receptors (GABA A R). While the pharmacological manipulation of GABA A R function by therapeutic agents, such as benzodiazepines can have profound effects on neuronal e
Autor:
Cody Kelley, Stephen J. Moss, Daniel Bitran, Ronald F. Mervis, Rachel Navarra, Raquel Revilla-Sanchez, Amy Sung, Mark Day, Guoming Zhang, Nicholas J. Brandon, Feng Liu, Luis C Muñiz, Karen L. Marquis, Warren D. Hirst, Robert L. Arias, Menelas N. Pangalos, Steven M. Grauer, Peter H. Reinhart, Virginia L. Pulito
Publikováno v:
Nature Neuroscience. 11:334-343
Estrogens have long been implicated in influencing cognitive processes, yet the molecular mechanisms underlying these effects and the roles of the estrogen receptors alpha (ERalpha) and beta (ERbeta) remain unclear. Using pharmacological, biochemical
Autor:
Miho Terunuma, Tommaso Fellin, David F. Meaney, Stephen J. Moss, Raquel Revilla-Sanchez, Marcello D'Ascenzo, Philip G. Haydon, Yves Auberson
Publikováno v:
Proceedings of the National Academy of Sciences. 104:1995-2000
Although metabotropic glutamate receptor 5 (mGluR5) is essential for cocaine self-administration and drug-seeking behavior, there is limited knowledge of the cellular actions of this receptor in the nucleus accumbens (NAc). Although mGluR5 has the po
Autor:
Olivier Pascual, Kristen B. Casper, Ken D. McCarthy, Cathryn Kubera, Jing Zhang, Stephen J. Moss, Jai Yoon Sul, Philip G. Haydon, Hajime Takano, Raquel Revilla-Sanchez
Publikováno v:
Science. 310:113-116
To investigate the role of astrocytes in regulating synaptic transmission, we generated inducible transgenic mice that express a dominant-negative SNARE domain selectively in astrocytes to block the release of transmitters from these glial cells. By
Autor:
Isabel M. Quadros, Michael J. Lumb, Raquel Revilla-Sanchez, Tarek Z. Deeb, Philip G. Haydon, Piotr Sicinski, Miho Terunuma, Stephen J. Moss, Menelas N. Pangalos, Qiudong Deng
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 34(3)
Cognitive dysfunction is a common symptom in many neuropsychiatric disorders and directly correlates with poor patient outcomes. The majority of prolonged inhibitory signaling in the brain is mediated via GABABreceptors (GABABRs), but the molecular f
Autor:
Rochelle M. Hines, Maribel Rios, Nicholas J. Brandon, Zhen Yan, Rachel Jurd, Stephen J. Moss, Miho Terunuma, Mansi Vithlani, Dustin J. Hines, Raquel Revilla-Sanchez, Phillip Haydon, Ping Zhong
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 33(39)
Brain-derived neurotrophic factor (BDNF) is a potent regulator of neuronal activity, neurogenesis, and depressive-like behaviors; however, downstream effectors by which BDNF exerts these varying actions remain to be determined. Here we reveal that BD
Autor:
Verena Tretter, Trevor G. Smart, Raquel Revilla-Sanchez, Stephen J. Moss, Damian P. Bright, Francesca Nani
GABA-mediated tonic and phasic inhibition of thalamic relay neurons of the dorsal lateral geniculate nucleus (dLGN) was studied after ablating tyrosine (Y) phosphorylation of receptor γ2-subunits. As phosphorylation of γ2 Y365 and Y367 reduces rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97b4bd1a47609b27f52fd1651a7fc6dc
https://europepmc.org/articles/PMC4400286/
https://europepmc.org/articles/PMC4400286/
Autor:
Jinghui Dong, Joshua G. Jackson, Stephen J. Moss, Menelas N. Pangalos, Philip G. Haydon, Graham C. R. Ellis-Davies, Luke I. Schmitt, Raquel Revilla-Sanchez, Peter H. Reinhart
Publikováno v:
Alzheimer's & Dementia. 6