Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Raquel P. Sen"'
Autor:
María Benito-León, Juan Carlos Gil-Redondo, Raquel Perez-Sen, Esmerilda G. Delicado, Felipe Ortega, Rosa Gomez-Villafuertes
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
P2X7 receptor (P2RX7) is expressed strongly by most human cancers, including neuroblastoma, where high levels of P2RX7 are correlated with a poor prognosis for patients. Tonic activation of P2X7 receptor favors cell metabolism and angiogenesis, there
Externí odkaz:
https://doaj.org/article/db86ea7c5b0849ac85ce2fa38eceb0d1
Autor:
Aida Menéndez-Méndez, Lucía Paniagua-Herranz, Luis A. Olivos-Oré, Rosa Gómez-Villafuertes, Raquel Pérez-Sen, Esmerilda G. Delicado, Antonio R. Artalejo, Felipe Ortega
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100964- (2021)
Summary: Low-density cell culture of the postnatal cerebellum, combined with live imaging and single-cell tracking, allows the behavior of postnatal cerebellar neural stem cells (NSCs) and their progeny to be monitored. Cultured cerebellar NSCs maint
Externí odkaz:
https://doaj.org/article/8c1d8c0273374a7580a20f18f218acef
Autor:
María T. Miras-Portugal, Aida Menéndez-Méndez, Rosa Gómez-Villafuertes, Felipe Ortega, Esmerilda G. Delicado, Raquel Pérez-Sen, Javier Gualix
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Vesicular storage of neurotransmitters, which allows their subsequent exocytotic release, is essential for chemical transmission in the central nervous system. Neurotransmitter uptake into secretory vesicles is carried out by vesicular transporters,
Externí odkaz:
https://doaj.org/article/44e48f989a864c858842de376f00b968
Autor:
Mª José Queipo, Juan C. Gil-Redondo, Verónica Morente, Felipe Ortega, Mª Teresa Miras-Portugal, Esmerilda G. Delicado, Raquel Pérez-Sen
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2018)
Extracellular signal-regulated kinases 1 and 2 (ERK1/2) play a central role in the intracellular signaling of P2X7 nucleotide receptors in neurons and glial cells. Fine spatio-temporal tuning of mitogen-activated protein (MAP) kinases is essential to
Externí odkaz:
https://doaj.org/article/4077c3e9a86346a789eddbb2ff23f086
Autor:
Raquel Pérez-Sen, Mª José Queipo, Verónica Morente, Felipe Ortega, Esmerilda G. Delicado, Mª Teresa Miras-Portugal
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 13, Iss C, Pp 160-168 (2015)
ADP-specific P2Y13 receptor constitutes one of the most recently identified nucleotide receptor and the understanding of their physiological role is currently under investigation. Cerebellar astrocytes and granule neurons provide excellent models to
Externí odkaz:
https://doaj.org/article/1ec1c1a596fe47edaf2b3337c10760c6
Autor:
Lucía Paniagua-Herranz, Juan C. Gil-Redondo, Ma José Queipo, Silvia González-Ramos, Lisardo Boscá, Raquel Pérez-Sen, Ma Teresa Miras-Portugal, Esmerilda G. Delicado
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Prostaglandin E2 (PGE2) is an important bioactive lipid that accumulates after tissue damage or inflammation due to the rapid expression of cyclooxygenase 2. PGE2 activates specific G-protein coupled EP receptors and it mediates pro- or anti-inflamma
Externí odkaz:
https://doaj.org/article/f7773beac3bd4060878b67f0719ffafa
Autor:
María Pimentel-Santillana, Paqui G. Través, Raquel Pérez-Sen, Esmerilda G. Delicado, Paloma Martín-Sanz, María Teresa Miras-Portugal, Lisardo Boscá
Publikováno v:
Mediators of Inflammation, Vol 2014 (2014)
The nucleotide uridine trisphosphate (UTP) released to the extracellular milieu acts as a signaling molecule via activation of specific pyrimidine receptors (P2Y). P2Y receptors are G protein-coupled receptors expressed in many cell types. These rece
Externí odkaz:
https://doaj.org/article/103443025af84c7ea95c9175cf92240c
Autor:
Javier Gualix, Rosa Gómez-Villafuertes, María Teresa Miras-Portugal, Jesús Pintor, Cristina Hervás, Lisandro Giraldez, Miguel Díaz-Hernández, Raquel P. Sen
Publikováno v:
Neurochemical Research. 28:1597-1605
ATP stimulates [Ca2+]i increases in midbrain synaptosomes via specific ionotropic receptors (P2X receptors). Previous studies have demonstrated the implication of P2X3 subunits in these responses, but additional P2X subunits must be involved. In the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::670ba78a6d140b591c5f7db72fcc0c34
https://doi.org/10.1023/a:1025690913206
https://doi.org/10.1023/a:1025690913206
Autor:
Enrique Castro, Raquel P. Sen, Florentina Soto, Marta Garcı́a-Lecea, Ma Teresa Miras-Portugal
Publikováno v:
Drug Development Research. 52:104-113
ATP is now recognized as a fast neurotransmitter after the demonstration of synaptic transmission mediated by ATP in the medial habenula, locus coeruleus, spinal cord, and hippocampus. We focused on the postnatal rat cerebellum as a model territory a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc55a4d637e7a75bee0965d104cfa877
https://doi.org/10.1002/ddr.1104
https://doi.org/10.1002/ddr.1104