Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Raquel Mejías-Luque"'
Autor:
Mona Wang, Xiaohan Fan, Boyang Huang, Kaifeng Pan, Markus Gerhard, Raquel Mejías‐Luque, Yang Zhang
Publikováno v:
Clinical and Translational Discovery, Vol 4, Iss 4, Pp n/a-n/a (2024)
Abstract Objective Screening and early diagnosis of gastric cancer (GC) are crucial for improved prognosis. However, gastroscopic screening is not feasible in large populations due to its high cost and invasive nature. The detection of circulating ce
Externí odkaz:
https://doaj.org/article/1d509c8ca41849c99ce2b326dee93e3d
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Infecting about half of the world´s population, Helicobacter pylori is one of the most prevalent bacterial infections worldwide and the strongest known risk factor for gastric cancer. Although H. pylori colonizes exclusively the gastric epithelium,
Externí odkaz:
https://doaj.org/article/59fc08264a3c4002b5c49ecf778e65a2
Autor:
Shiqi Luo, Jinlong Ru, Mohammadali Khan Mirzaei, Jinling Xue, Xue Peng, Anna Ralser, Raquel Mejías-Luque, Markus Gerhard, Li Deng
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTColorectal cancer (CRC) is one of the most commonly diagnosed cancers worldwide. While a close correlation between chronic Helicobacter pylori infection and CRC has been reported, the role of the virome has been overlooked. Here, we infected
Externí odkaz:
https://doaj.org/article/914eda00e93244bb96b6cfade8c64dd4
Autor:
Lei Peng, Yang Guo, Markus Gerhard, Juan-Juan Gao, Zong-Chao Liu, Raquel Mejías-Luque, Lian Zhang, Michael Vieth, Jun-Ling Ma, Wei-Dong Liu, Zhe-Xuan Li, Tong Zhou, Wen-Qing Li, Wei-Cheng You, Yang Zhang, Kai-Feng Pan
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Metabolites and their interactions with microbiota may be involved in Helicobacter pylori-associated gastric lesion development. This study aimed to explore metabolite alterations upon H. pylori eradication and possible roles of microbiota-m
Externí odkaz:
https://doaj.org/article/8bd89e4f513045e78eee2d82d437d3e4
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Helicobacter pylori has developed several strategies using its diverse virulence factors to trigger and, at the same time, limit the host’s inflammatory responses in order to establish a chronic infection in the human stomach. One of the virulence
Externí odkaz:
https://doaj.org/article/b6dbb517cb0a4886af4c0edb9bab415f
Loss of RNF43 Function Contributes to Gastric Carcinogenesis by Impairing DNA Damage ResponseSummary
Autor:
Victoria Neumeyer, Anna Brutau-Abia, Michael Allgäuer, Nicole Pfarr, Wilko Weichert, Christina Falkeis-Veits, Elisabeth Kremmer, Michael Vieth, Markus Gerhard, Raquel Mejías-Luque
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1071-1094 (2021)
Background & Aims: RING finger protein 43 (RNF43) is a tumor suppressor that frequently is mutated in gastric tumors. The link between RNF43 and modulation of Wingless-related integration site (WNT) signaling has not been shown clearly in the stomach
Externí odkaz:
https://doaj.org/article/472f9999d5b54f16995372b20c368717
Autor:
Raquel Mejías-Luque, PhD
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 3, Pp 887-888 (2021)
Externí odkaz:
https://doaj.org/article/18953c9510c24ff2b736174d9f88f650
Autor:
Karin Taxauer, Youssef Hamway, Anna Ralser, Alisa Dietl, Karin Mink, Michael Vieth, Bernhard B. Singer, Markus Gerhard, Raquel Mejías-Luque
Publikováno v:
Microorganisms, Vol 9, Iss 8, p 1748 (2021)
The gastric pathogen Helicobacter pylori infects half of the world’s population and is a major risk factor for gastric cancer development. In order to attach to human gastric epithelial cells and inject the oncoprotein CagA into host cells, H. pylo
Externí odkaz:
https://doaj.org/article/c84561a48e9a48209bfb2b551822edd8
Autor:
Sonakshi Bhattacharjee, Raquel Mejías-Luque, Eva Loffredo-Verde, Albulena Toska, Michael Flossdorf, Markus Gerhard, Clarissa Prazeres da Costa
Publikováno v:
Cell Reports, Vol 28, Iss 1, Pp 231-244.e5 (2019)
Summary: Helicobacter pylori chronically colonizes the stomach and is strongly associated with gastric cancer. Its concomitant occurrence with helminths such as schistosomes has been linked to reduced cancer incidence, presumably due to suppression o
Externí odkaz:
https://doaj.org/article/8b9a036f91b84a4f9ffc22034bf0bd59
Autor:
Youssef Hamway, Karin Taxauer, Kristof Moonens, Victoria Neumeyer, Wolfgang Fischer, Verena Schmitt, Bernhard B. Singer, Han Remaut, Markus Gerhard, Raquel Mejías-Luque
Publikováno v:
Microorganisms, Vol 8, Iss 4, p 465 (2020)
Attachment to the host gastric mucosa is a key step in Helicobacter pylori infection. Recently, a novel adhesin, HopQ, was shown to bind distinct host CEACAM proteins—an interaction that was found to be essential for the translocation of CagA, a ke
Externí odkaz:
https://doaj.org/article/d66be523afd448259fc491fb79ea468a