Výsledky vyhledávání - "Raquel Matavele Chissumba"

Akademický článek

HIV incidence and its associated factors among young adults with multiple sexual partners in Maputo, Mozambique: a vaccine preparedness study

Publikováno v: BMC Public Health, Vol 24, Iss 1, Pp 1-11 (2024)

Abstract Introduction Sub-Saharan Africa has a high burden of HIV, particularly among female sex workers (FSW) and men who have sex with men (MSM). Future clinical trials to evaluate vaccines and other interventions to prevent HIV will need to enroll

Externí odkaz: https://doaj.org/article/1beb0da763a5476791b223fca0563eb8

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Helios expressing regulatory T cells are correlated with decreased IL-2 producing CD8 T cells and antibody diversity in Mozambican individuals living chronically with HIV-1

Autor: Raquel Matavele Chissumba, Cacildo Magul, Rosa Macamo, Vânia Monteiro, Maria Enosse, Ivalda Macicame, Victória Cumbane, Nilesh Bhatt, Edna Viegas, Michelle Imbach, Leigh Anne Eller, Christina S. Polyak, Luc Kestens, for the RV363 Study Group

Publikováno v: BMC Immunology, Vol 23, Iss 1, Pp 1-9 (2022)

Abstract Background Human immunodeficiency virus type 1 (HIV-1) causes impairment of T and B cell responses, which begins during the acute phase of infection and is not completely restored by antiretroviral treatment. Regulatory T cell (Tregs) can im

Externí odkaz: https://doaj.org/article/46635a86ed3e441ea10b159604acf482

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Tuberculosis Treatment Response Monitoring by the Phenotypic Characterization of MTB-Specific CD4+ T-Cells in Relation to HIV Infection Status

Autor: Nádia Sitoe, Mohamed I. M. Ahmed, Maria Enosse, Abhishek Bakuli, Raquel Matavele Chissumba, Kathrin Held, Michael Hoelscher, Pedroso Nhassengo, Celso Khosa, Andrea Rachow, Christof Geldmacher, on behalf of TB Sequel Consortium

Publikováno v: Pathogens, Vol 11, Iss 9, p 1034 (2022)

HIV infection causes systemic immune activation, impacts TB disease progression and hence may influence the diagnostic usability of Mycobacterium tuberculosis-specific T cell profiling. We investigated changes of activation and maturation markers on

Externí odkaz: https://doaj.org/article/df7a1046d54b4b0d86a6ff6bcdbd545a

Zobrazit plný text záznamu

Akademický článek

Vaccine-Induced Seroreactivity Impacts the Accuracy of HIV Testing Algorithms in Sub-Saharan Africa: An Exploratory Study

Autor: Frank Msafiri, Alice Manjate, Sarah Lindroth, Nelson Tembe, Raquel Matavele Chissumba, Victoria Cumbane, Ilesh Jani, Said Aboud, Eligius Lyamuya, Sören Andersson, Charlotta Nilsson

Publikováno v: Vaccines, Vol 10, Iss 7, p 1062 (2022)

The detection of vaccine-induced HIV antibody responses by rapid diagnostic tests (RDTs) may confound the interpretation of HIV testing results. We assessed the impact of vaccine-induced seroreactivity (VISR) on the diagnosis of HIV in sub-Saharan Af

Externí odkaz: https://doaj.org/article/b29e5c853a744d4ca03dc7e4ce443eda

Zobrazit plný text záznamu

Akademický článek

Determining hematological, biochemical and immunological reference values in healthy adults with high-risk for HIV acquisition in Mozambique.

Autor: Victória Cumbane, Michelle Imbach, Raquel Matavele Chissumba, Ivalda Macicame, Leigh Anne Eller, John Lawlor, Mark Milazzo, Qun Li, Trevor Crowell, Mirna Mutombene, Onélia Guiliche, Edna Viegas, Chiaka Nwoga, Adam Yates, Nelson Michael, Merlin Robb, Christina S Polyak, Ilesh V Jani, Nilesh Bhatt

Publikováno v: PLoS ONE, Vol 15, Iss 4, p e0232018 (2020)

INTRODUCTION:In many African countries, laboratory reference values are not established for the local healthy adult population. In Mozambique, reference values are known for young adults (18-24yo) but not yet established for a wider age range. Our st

Externí odkaz: https://doaj.org/article/2622b11e8fb54a97825da4fea9582226

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Helios + Regulatory T cell frequencies are correlated with control of viral replication and recovery of absolute CD4 T cells counts in early HIV-1 infection

Autor: Raquel Matavele Chissumba, Eduardo Namalango, Vânia Maphossa, Ivalda Macicame, Nilesh Bhatt, Christina Polyak, Merlin Robb, Nelson Michael, Ilesh Jani, Luc Kestens

Publikováno v: BMC Immunology, Vol 18, Iss 1, Pp 1-10 (2017)

Abstract Background The acute phase of HIV infection is characterized by massive depletion of CD4 T cells, high viral plasma levels and pronounced systemic immune activation. Regulatory T cells (Tregs) have the potential to control systemic immune ac

Externí odkaz: https://doaj.org/article/6dfaf5dbcacd41b0af1aed22287c1693

Zobrazit plný text záznamu

Akademický článek

HIV prevalence and risk behavior among male and female adults screened for enrolment into a vaccine preparedness study in Maputo, Mozambique.

Autor: Ivalda Macicame, Nilesh Bhatt, Raquel Matavele Chissumba, Leigh Anne Eller, Edna Viegas, Khelvon Araújo, Chiaka Nwoga, Qun Li, Mark Milazzo, Nancy K Hills, Christina Lindan, Nelson L Michael, Merlin L Robb, Ilesh Jani, Christina S Polyak

Publikováno v: PLoS ONE, Vol 14, Iss 9, p e0221682 (2019)

IntroductionMozambique continues to have a significant burden of HIV. Developing strategies to control the HIV epidemic remains a key priority for the Mozambican public health community. The primary aim of this study was to determine HIV prevalence a

Externí odkaz: https://doaj.org/article/46959e55f5bb44bd9428d5b2bc9c2e10

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Frequent Anti-V1V2 Responses Induced by HIV-DNA Followed by HIV-MVA with or without CN54rgp140/GLA-AF in Healthy African Volunteers

Publikováno v: Microorganisms, Vol 8, Iss 11, p 1722 (2020)

Antibody responses that correlated with reduced risk of HIV acquisition in the RV144 efficacy trial were assessed in healthy African volunteers who had been primed three times with HIV-DNA (subtype A, B, C) and then randomized into two groups; group

Externí odkaz: https://doaj.org/article/33fc5d4954f946749c536f9a5caab9a1

Zobrazit plný text záznamu