Cannabidiol Administered During Peri-Adolescence Prevents Behavioral Abnormalities in an Animal Model of Schizophrenia

Autor: Fernanda F. Peres, Mariana C. Diana, Raquel Levin, Mayra A. Suiama, Valéria Almeida, Ana M. Vendramini, Camila M. Santos, Antônio W. Zuardi, Jaime E. C. Hallak, José A. Crippa, Vanessa C. Abílio

Publikováno v: Frontiers in Pharmacology, Vol 9 (2018)

Schizophrenia is considered a debilitating neurodevelopmental psychiatric disorder and its pharmacotherapy remains problematic without recent major advances. The development of interventions able to prevent the emergence of schizophrenia would theref

Externí odkaz: https://doaj.org/article/6f796365de5540d0bacde8ab81643bd9

Cannabidiol prevents motor and cognitive impairments induced by reserpine in rats

Autor: Fernanda Fiel Peres, Raquel Levin, Mayra Akimi Suiama, Mariana Cepollaro Diana, Douglas Albuquerque Gouvêa, Valéria Almeida, Camila Maurício Santos, Lisandro Lungato, Antonio Waldo Zuardi, Jaime Eduardo Hallak, José Alexandre Crippa, Vânia D'Almeida, Regina H Silva, Vanessa Costhek Abilio

Publikováno v: Frontiers in Pharmacology, Vol 7 (2016)

Cannabidiol (CBD) is a non-psychotomimetic compound from Cannabis sativa that presents antipsychotic, anxiolytic, anti-inflammatory and neuroprotective effects. In Parkinson’s disease patients, CBD is able to attenuate the psychotic symptoms induce

Externí odkaz: https://doaj.org/article/73eab18f35c84a5db5ada36df6d955ff

Role of the endocannabinoid and endovanilloid systems in an animal model of schizophrenia-related emotional processing/cognitive deficit

Autor: Camila M. Santos, Fernanda Fiel Peres, Antonio Waldo Zuardi, José Alexandre de Souza Crippa, Valéria de Almeida, Ana Maria Vendramini, Mayra Akimi Suiama, Jaime Eduardo Cecílio Hallak, Raquel Levin, Neide Derci da Silva, Vanessa C. Abílio

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Studies suggest that the endocannabinoid and endovanilloid systems are implicated in the pathophysiology of schizophrenia. The Spontaneously Hypertensive Rats (SHR) strain displays impaired contextual fear conditioning (CFC) attenuated by antipsychot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfce144779391d03e2c19dbea429d1ac
https://pubmed.ncbi.nlm.nih.gov/31103618

Cannabidiol Prevents Motor and Cognitive Impairments Induced by Reserpine in Rats

Autor: Valéria de Almeida, José Alexandre de Souza Crippa, Antonio Waldo Zuardi, Regina H. Silva, Fernanda Fiel Peres, Lisandro Lungato, Vanessa C. Abílio, Raquel Levin, Mariana Cepollaro Diana, Camila M. Santos, Jaime Eduardo Cecílio Hallak, Mayra Akimi Suiama, Douglas Albuquerque Gouvea, D’Almeida Vânia

Publikováno v: Frontiers in Pharmacology
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Frontiers in Pharmacology, Vol 7 (2016)

Cannabidiol (CBD) is a non-psychotomimetic compound from Cannabis sativa that presents antipsychotic, anxiolytic, anti-inflammatory, and neuroprotective effects. In Parkinson’s disease patients, CBD is able to attenuate the psychotic symptoms induc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30c0187276c0e8b56cc3111fd2b265dc

The contextual fear conditioning deficit presented by spontaneously hypertensive rats (SHR) is not improved by mood stabilizers

Autor: Raquel Levin, Rosana de A. Ribeiro, Vanessa C. Abílio, Mariana Bendlin Calzavara, Tânia Cristina Libânio, Wladimir Agostini Medrano

Publikováno v: Progress in Neuro-Psychopharmacology and Biological Psychiatry. 35(7):1607-1611

Objectives We have recently reported that spontaneously hypertensive rats (SHR) present a contextual fear conditioning (CFC) deficit. This deficit is improved by antipsychotic drugs, potentiated by proschizophrenia manipulations and not altered by ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3061718e5b3d9f4569712b089f83b01c