Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Raquel Hladun"'
Autor:
Maria Eugénia Marques Da Costa, Sakina Zaidi, Jean-Yves Scoazec, Robin Droit, Wan Ching Lim, Antonin Marchais, Jerome Salmon, Sarah Cherkaoui, Raphael J. Morscher, Anouchka Laurent, Sébastien Malinge, Thomas Mercher, Séverine Tabone-Eglinger, Isabelle Goddard, Francoise Pflumio, Julien Calvo, Francoise Redini, Natacha Entz-Werlé, Aroa Soriano, Alberto Villanueva, Stefano Cairo, Pascal Chastagner, Massimo Moro, Cormac Owens, Michela Casanova, Raquel Hladun-Alvaro, Pablo Berlanga, Estelle Daudigeos-Dubus, Philippe Dessen, Laurence Zitvogel, Ludovic Lacroix, Gaelle Pierron, Olivier Delattre, Gudrun Schleiermacher, Didier Surdez, Birgit Geoerger
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-15 (2023)
Abstract Pediatric patients with recurrent and refractory cancers are in most need for new treatments. This study developed patient-derived-xenograft (PDX) models within the European MAPPYACTS cancer precision medicine trial (NCT02613962). To date, 1
Externí odkaz:
https://doaj.org/article/0bccef955fcd4460a5c66a0d211aaac0
Autor:
Julia C. Chisholm, Reineke A. Schoot, Alison L. Cameron, Michela Casanova, Veronique Minard-Colin, Beatrice Coppadoro, Marta Garrido, Timothy Rogers, Daniel Orbach, Heidi Glosli, Miriam Ben-Arush, Sima Ferman, Giovanni Scarzello, Rick R. van Rijn, Raquel Hladun, Nadege Corradini, Andrea Ferrari, Meriel Jenney, Gianni Bisogno, Johannes H.M. Merks
Publikováno v:
EJC Paediatric Oncology, Vol 2, Iss , Pp 100018- (2023)
Purpose: Patients with metastatic rhabdomyosarcoma (MTS RMS) and lung as the only metastatic site have better reported outcomes than other patients with MTS RMS. We analysed patients with lung-only MTS RMS receiving standard treatment within the EpSS
Externí odkaz:
https://doaj.org/article/bb8c7f0da2cc492fb4de7fd1fd83622f
Autor:
Gianni Bisogno, Gian Luca De Salvo, Veronique Minard-Colin, Raquel Davila Fajardo, Beatrice Coppadoro, Meriel Jenney, Andrea Ferrari, Raquel Hladun Alvaro, Patrizia Dall’Igna, Heidi Glosli, Johannes H.M. Merks
Publikováno v:
EJC Paediatric Oncology, Vol 1, Iss , Pp 100014- (2023)
Purpose: Clinical trials include a series of eligibility and exclusion criteria that define the study population to reduce inter-patient heterogeneity and increase safety. Little is known about children with oncological diseases excluded from trials
Externí odkaz:
https://doaj.org/article/7bc21c17f49a4e12b93d89c5f21d0bda
Autor:
Julián Sevilla, Susana Navarro, Paula Rio, Rebeca Sánchez-Domínguez, Josune Zubicaray, Eva Gálvez, Eva Merino, Elena Sebastián, Carmen Azqueta, José A. Casado, José C. Segovia, Omaira Alberquilla, Massimo Bogliolo, Francisco J. Román-Rodríguez, Yari Giménez, Lise Larcher, Rocío Salgado, Roser M. Pujol, Raquel Hladun, Ana Castillo, Jean Soulier, Sergi Querol, Jesús Fernández, Jonathan Schwartz, Nagore García de Andoín, Ricardo López, Albert Catalá, Jordi Surralles, Cristina Díaz-de-Heredia, Juan A. Bueren
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss , Pp 66-75 (2021)
Difficulties in the collection of hematopoietic stem and progenitor cells (HSPCs) from Fanconi anemia (FA) patients have limited the gene therapy in this disease. We have investigated (ClinicalTrials.gov, NCT02931071) the safety and efficacy of filgr
Externí odkaz:
https://doaj.org/article/ff619351134c4b8d89b9a48f91e2e8e9
Autor:
Laura Escudero, Anna Llort, Alexandra Arias, Ander Diaz-Navarro, Francisco Martínez-Ricarte, Carlota Rubio-Perez, Regina Mayor, Ginevra Caratù, Elena Martínez-Sáez, Élida Vázquez-Méndez, Iván Lesende-Rodríguez, Raquel Hladun, Luis Gros, Santiago Ramón y Cajal, Maria A. Poca, Xose S. Puente, Juan Sahuquillo, Soledad Gallego, Joan Seoane
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Non-invasive and precise methods are critical for monitoring paediatric brain cancers. Here the authors show that the molecular alterations and heterogeneity of paediatric medulloblastomas can be reliably detected in circulating tumour DNA from the c
Externí odkaz:
https://doaj.org/article/c3bf556831fd4765979786b61390d38a
Autor:
Luz Jubierre, Carlos Jiménez, Eric Rovira, Aroa Soriano, Constantino Sábado, Luis Gros, Anna Llort, Raquel Hladun, Josep Roma, Josep Sánchez de Toledo, Soledad Gallego, Miguel F. Segura
Publikováno v:
Experimental and Molecular Medicine, Vol 50, Iss 4, Pp 1-12 (2018)
Cancer therapy: Exploring an epigenetic approach Treatments that target chromatin, the combination of DNA and proteins, are emerging as alternative ways to treat aggressive neuroblastomas, cancers of neural tissue. Altering the structure and function
Externí odkaz:
https://doaj.org/article/44a3f605201c49468d79e2635c1fc5f8
Autor:
Irina Giralt, Gabriel Gallo-Oller, Natalia Navarro, Patricia Zarzosa, Guillem Pons, Ainara Magdaleno, Miguel F. Segura, Constantino Sábado, Raquel Hladun, Diego Arango, José Sánchez de Toledo, Lucas Moreno, Soledad Gallego, Josep Roma
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 12921 (2021)
The Wnt/β-catenin signaling pathway plays a pivotal role during embryogenesis and its deregulation is a key mechanism in the origin and progression of several tumors. Wnt antagonists have been described as key modulators of Wnt/β-catenin signaling
Externí odkaz:
https://doaj.org/article/427ff2b3d2834e329df4e183f7b4331d
Autor:
Bisogno, Gianni, De Salvo, Gian Luca, Minard-Colin, Veronique, Fajardo, Raquel Davila, Coppadoro, Beatrice, Jenney, Meriel, Ferrari, Andrea, Alvaro, Raquel Hladun, Dall’Igna, Patrizia, Glosli, Heidi, Merks, Johannes H.M.
Publikováno v:
In EJC Paediatric Oncology 2023 1
Akademický článek
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Autor:
Birgit Geoerger, Gudrun Schleiermacher, Gilles Vassal, Olivier Delattre, Stefan Michiels, Raquel Hladun-Alvaro, Cormac Owens, Michela Casanova, Estelle Thebaud, Isabelle Aerts, Nicolas André, Nadege Corradini, Samuel Abbou, Arnaud Gauthier, Jean-Yves Scoazec, Sophie Cotteret, Virginie Bernard, Cecile Chevassus, Imene Hezam, Aroa Soriano Fernandez, Alicia Larive, Yasmine Iddir, Anne C. Harttrampf, Antonin Marchais, Tiphaine Adam de Beaumais, Mathieu Chicard, Ludovic Lacroix, Gaelle Pierron, Pablo Berlanga
MAPPYACTS (NCT02613962) is an international prospective precision medicine trial aiming to define tumor molecular profiles in pediatric patients with recurrent/refractory malignancies in order to suggest the most adapted salvage treatment. From Febru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64eb555be534385db493fab181dc33a6
https://doi.org/10.1158/2159-8290.c.6549526
https://doi.org/10.1158/2159-8290.c.6549526
