Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Raquel Gutiérrez-Abad"'
Autor:
Ona Illa, Rosa M. Ortuño, Raquel Gutiérrez-Abad, Jimena Ospina, Vicenç Branchadell, Silvia Lope-Piedrafita
Publikováno v:
Tetrahedron. 71:8085-8095
Several chiral cyclobutane-containing chemical platforms were synthesized in a stereoselective manner starting from (−)-verbenone as a suitable precursor. These compounds bear three orthogonally protected amine functions, two of them on side-chain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dc2e085ba0006defafbc148cfe58929
https://doi.org/10.1016/j.tet.2015.08.044
https://doi.org/10.1016/j.tet.2015.08.044
Autor:
Ona Illa, Pau Nolis, Carles Acosta, Jordi Aguilera, Rosa M. Ortuño, Raquel Gutiérrez-Abad, Juan A. Cobos
Publikováno v:
European Journal of Organic Chemistry. 2013:3494-3503
Three series of new γ-peptides have been synthesized by starting from conveniently protected cis-3-amino-2,2-dimethylcyclobutane-1-carboxylic acid derivatives. The first series is constructed with only one enantiomer of this γ-amino acid, whereas i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2cb4fa7286ff5e9731d524a7c5dd678
https://doi.org/10.1002/ejoc.201300066
https://doi.org/10.1002/ejoc.201300066
Autor:
Graciela Y. Moltrasio, Àlex Mor, Jordi Aguilera, Rosa M. Ortuño, Albertina G. Moglioni, Raquel Gutiérrez-Abad
Publikováno v:
Tetrahedron: Asymmetry. 19:2864-2869
Alternative synthetic routes are provided to synthesize γ-amino acids in their free form or conveniently protected for their selective incorporation into ramified γ-peptides with a cyclobutane core. The key synthetic-step involves the stereoselecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0a54b42abfff16a3b6eb598db0d651a
https://doi.org/10.1016/j.tetasy.2008.12.019
https://doi.org/10.1016/j.tetasy.2008.12.019
Autor:
Chiara Cabrele, Oliver Reiser, Günther Bernhardt, Rosa M. Ortuño, Raquel Gutiérrez-Abad, Łukasz Berlicki, Melanie Kaske, Armin Buschauer, Ona Illa
Publikováno v:
Journal of medicinal chemistry. 56(21)
Neuropeptide Y (NPY) and pancreatic polypeptide (PP) control central and peripheral processes by activating the G protein coupled receptors YxR (x = 1, 2, 4, 5). We present analogs of the C-terminal fragments 25-36 and 32-36 of NPY and PP containing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7659ba2da23e4773062653e0467f342d
https://pubmed.ncbi.nlm.nih.gov/24090364
https://pubmed.ncbi.nlm.nih.gov/24090364
Autor:
Miriam Royo, Daniel Carbajo, Rosa M. Ortuño, Raquel Gutiérrez-Abad, Ona Illa, Esther Gorrea, Vicenç Branchadell
Publikováno v:
Organicbiomolecular chemistry. 10(20)
Two generations of hybrid γ,γ-peptides containing cyclobutane amino acids and cis-γ-amino-L-proline joined in alternation have been synthesized and their capacity to cross the eukaryotic cell membrane has been evaluated. The first generation consi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc57698d5252cc090ab2c48c2bfae324
https://pubmed.ncbi.nlm.nih.gov/22514076
https://pubmed.ncbi.nlm.nih.gov/22514076
Autor:
Juan A. Cobos, Carles Acosta-Silva, Pau Nolis, Ona Illa, Daniel Carbajo, Miriam Royo, Rosa M. Ortuño, Raquel Gutiérrez-Abad
Publikováno v:
Amino acids. 41(3)
Two diastereomeric series of hybrid γ,γ-peptides derived from conveniently protected derivatives of (1R,2S)- and (1S,2R)-3-amino-2,2-dimethylcyclobutane-1-carboxylic acid and cis-4-amino-L: -proline joined in alternation have efficiently been prepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44acfc3fc4d6efa87889bed5b06f952b
https://pubmed.ncbi.nlm.nih.gov/21541681
https://pubmed.ncbi.nlm.nih.gov/21541681
Publikováno v:
Organic letters. 12(14)
Five new highly functionalized cyclobutane containing C(3)-symmetric peptide dendrimers have been synthesized through a convergent approach from 1,3,5-trisubstituted benzene and chiral gamma,epsilon-amino diacid derivatives as well as a gamma-tetrape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::105d81712137a7abc2b656ff1bf6eb86
https://pubmed.ncbi.nlm.nih.gov/20545312
https://pubmed.ncbi.nlm.nih.gov/20545312
Publikováno v:
Organic Letters; Jul2010, Vol. 12 Issue 14, p3148-3151, 4p