Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Raquel Godoy‐Ruiz"'
Autor:
Rodrigo Lázaro‐Gorines, Patricia Pérez, Ignacio Heras‐Murillo, Irene Adán‐Barrientos, Guillermo Albericio, David Astorgano, Sara Flores, Joanna Luczkowiak, Nuria Labiod, Seandean L. Harwood, Alejandro Segura‐Tudela, Laura Rubio‐Pérez, Yudhi Nugraha, Xiaoran Shang, Yuxing Li, Carlos Alfonso, Kaylin A. Adipietro, Dinendra L. Abeyawardhane, Rocío Navarro, Marta Compte, Wenbo Yu, Alexander D. MacKerell Jr, Laura Sanz, David J. Weber, Francisco J. Blanco, Mariano Esteban, Edwin Pozharski, Raquel Godoy‐Ruiz, Inés G. Muñoz, Rafael Delgado, David Sancho, Juan García‐Arriaza, Luis Álvarez‐Vallina
Publikováno v:
Advanced Science, Vol 10, Iss 34, Pp n/a-n/a (2023)
Abstract Administration of neutralizing antibodies (nAbs) has proved to be effective by providing immediate protection against SARS‐CoV‐2. However, dual strategies combining virus neutralization and immune response stimulation to enhance specific
Externí odkaz:
https://doaj.org/article/83ee823ecfc342e88a1c1efafa321622
Autor:
Yingwei Chen, Eric A. Toth, Biao Ruan, Eun Jung Choi, Richard Simmerman, Yihong Chen, Yanan He, Ruixue Wang, Raquel Godoy-Ruiz, Harlan King, Gregory Custer, D. Travis Gallagher, David A. Rozak, Melani Solomon, Silvia Muro, David J. Weber, John Orban, Thomas R. Fuerst, Philip N. Bryan
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Chen et al. describe a rational design of subtilisin mutants that degrade active RAS by cleaving a conserved sequence in switch 2. They further modified the active site to be dependent on a cofactor to generate high target specificity. Proteases engi
Externí odkaz:
https://doaj.org/article/742c1a3e0584400b8b631c6e4a1b0ff6
Autor:
Namita Kundu, Xinrong Ma, Stephen Hoag, Fang Wang, Ahmed Ibrahim, Raquel Godoy-Ruiz, David J Weber, Amy M Fulton
Publikováno v:
Breast Cancer: Basic and Clinical Research, Vol 15 (2021)
The taro plant, Colocasia esculenta , contains bioactive proteins with potential as cancer therapeutics. Several groups have reported anti-cancer activity in vitro and in vivo of taro-derived extracts (TEs). We reported that TE inhibits metastasis in
Externí odkaz:
https://doaj.org/article/08caf4f55c5a4bdf8a5779f2f86e5af3
Akademický článek
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Autor:
John Orban, Yihong Chen, Yanan He, David J. Weber, Eun Jung Choi, Raquel Godoy-Ruiz, Biao Ruan, D. Travis Gallagher, Melani Solomon, Thomas R. Fuerst, Ruixue Wang, David A. Rozak, Gregory S. Custer, Philip N. Bryan, Harlan King, Silvia Muro, Eric A. Toth, Yingwei Chen, Richard Simmerman
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Communications Biology
Communications Biology
We describe the design, kinetic properties, and structures of engineered subtilisin proteases that degrade the active form of RAS by cleaving a conserved sequence in switch 2. RAS is a signaling protein that, when mutated, drives a third of human can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::768ae163ddb6ebc0c904ea01793832d2
https://doaj.org/article/742c1a3e0584400b8b631c6e4a1b0ff6
https://doaj.org/article/742c1a3e0584400b8b631c6e4a1b0ff6
Publikováno v:
Biomolecular Nmr Assignments
Clostridioides difficile is a bacterial pathogen responsible for the majority of nosocomial infections in the developed world. C. difficile infection (CDI) is difficult to treat in many cases because hypervirulent strains have evolved that contain a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06293847d69920f0ae944ce32ecea0ea
https://doi.org/10.1007/s12104-020-09979-y
https://doi.org/10.1007/s12104-020-09979-y
Publikováno v:
Biomolecular Nmr Assignments
Vitamin A is a necessary nutrient for all mammals, and it is required for the transcription of many genes and vital for vision. While fasting, the vitamin A alcohol form (Retinol) from storage in the liver is mobilized and transported through the blo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06196512384712b175d3ff1a7c93b1cb
http://europepmc.org/articles/PMC7154012
http://europepmc.org/articles/PMC7154012
Autor:
Kaylin A. Adipietro, Kristen M. Varney, Dinendra L Abeyawardhane, David J. Weber, Edwin Pozharski, Raquel Godoy-Ruiz
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f50c0542516439ff429f88a357263deb
https://doi.org/10.1096/fasebj.2021.35.s1.04607
https://doi.org/10.1096/fasebj.2021.35.s1.04607
Autor:
David J. Weber, Kaylin A. Adipietro, Raquel Godoy-Ruiz, Richard R. Rustandi, Dinendra L Abeyawardhane, E. Pozharski, Kristen M. Varney
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2926, p 2926 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Novel therapeutics are needed to treat pathologies associated with the Clostridioides difficile binary toxin (CDT), particularly when C. difficile infection (CDI) occurs in the elderly or in hospitalized patients having illnesses, in addition to CDI,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cae709f02a64e5e700d76dcc5a804ffb
https://www.mdpi.com/1422-0067/22/6/2926
https://www.mdpi.com/1422-0067/22/6/2926
Autor:
Namita, Kundu, Xinrong, Ma, Stephen, Hoag, Fang, Wang, Ahmed, Ibrahim, Raquel, Godoy-Ruiz, David J, Weber, Amy M, Fulton
Publikováno v:
Breast Cancer : Basic and Clinical Research
The taro plant, Colocasia esculenta, contains bioactive proteins with potential as cancer therapeutics. Several groups have reported anti-cancer activity in vitro and in vivo of taro-derived extracts (TEs). We reported that TE inhibits metastasis in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::712b6c933c2c0c4a6379dd4f0eb4a819
https://pubmed.ncbi.nlm.nih.gov/34376983
https://pubmed.ncbi.nlm.nih.gov/34376983