Výsledky vyhledávání - "Raquel Gasque"

Akademický článek

Clinical trajectories of patients with multiple sclerosis from onset and their relationship with serum neurofilament light chain levels

Autor: Carlos Quintanilla-Bordás, Laura Cubas-Núñez, Jéssica Castillo-Villalba, Sara Carratalá-Boscá, Raquel Gasque-Rubio, Jordi Tortosa-Carreres, Carmen Alcalá, Lorena Forés-Toribio, Celia Lucas, David Gorriz, Francisco Pérez-Miralles, Bonaventura Casanova

Publikováno v: Frontiers in Neurology, Vol 15 (2024)

BackgroundSerum neurofilament light chain (sNfL) is a biomarker of neuroaxonal destruction that correlates with acute inflammation (AI) in multiple sclerosis (MS). However, in the treatment era, progression without AI is the main driver of long-term

Externí odkaz: https://doaj.org/article/67253ab10c5a429da0f649fed3c9eb0c

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Akademický článek

Case Report: Exacerbation of Relapses Following mRNA COVID-19 Vaccination in Multiple Sclerosis: A Case Series

Autor: Carlos Quintanilla-Bordás, Francisco Gascón-Gimenez, Carmen Alcalá, María Payá, Javier Mallada, Raquel Silla, Sara Carratalà-Boscà, Raquel Gasque-Rubio, Jessica Castillo, Bonaventura Casanova

Publikováno v: Frontiers in Neurology, Vol 13 (2022)

IntroductionmRNA coronavirus disease 2019 (COVID-19) vaccination has been widely used to arrest the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. Rarely, autoimmune events such as relapses in patients with multi

Externí odkaz: https://doaj.org/article/88844609842a4dbd8a15baee29893f00

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Akademický článek

High Levels of Cerebrospinal Fluid Kappa Free Light Chains Relate to IgM Intrathecal Synthesis and Might Have Prognostic Implications in Relapsing Multiple Sclerosis

Autor: Jéssica Castillo-Villalba, Sara Gil-Perotín, Raquel Gasque-Rubio, Laura Cubas-Nuñez, Sara Carratalà-Boscà, Carmen Alcalá, Carlos Quintanilla-Bordás, Francisco Pérez-Miralles, Cristina Ferrer, Antonio Cañada Martínez, Jordi Tortosa, Luís Solís-Tarazona, Luisa Campos, Alberto Leivas, Begoña Laíz Marro, Bonaventura Casanova

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Cerebrospinal kappa free light chain (KFLC)-index is a marker of intrathecal immunoglobulin synthesis that aids in the diagnosis of multiple sclerosis (MS). However, little evidence exists on its prognostic role. Our aim is to analyze the relationshi

Externí odkaz: https://doaj.org/article/b2a1c9817f794ef9b56f12e0b8ea37c3

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Akademický článek

Combined Cerebrospinal Fluid Neurofilament Light Chain Protein and Chitinase-3 Like-1 Levels in Defining Disease Course and Prognosis in Multiple Sclerosis

Autor: Sara Gil-Perotin, Jessica Castillo-Villalba, Laura Cubas-Nuñez, Raquel Gasque, David Hervas, Josep Gomez-Mateu, Carmen Alcala, Francisco Perez-Miralles, Francisco Gascon, Jose Andres Dominguez, Bonaventura Casanova

Publikováno v: Frontiers in Neurology, Vol 10 (2019)

Background: Neurofilament light chain protein (NFL) and chitinase3-like1 (CHI3L1) have gained importance recently as prognostic biomarkers in multiple sclerosis (MS).Objectives: We aimed to investigate NFL and CHI3L1 cerebrospinal fluid (CSF) profile

Externí odkaz: https://doaj.org/article/13f821624bc540a8b1285c29b182d2b3

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Akademický článek

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Oligoclonal M bands unveil occult inflammation in multiple sclerosis

Autor: Bonaventura Casanova, Jessica Castillo, Carlos Quintanilla-Bordás, María T. Sanz, Jose I Fernández-Velasco, Carmen Alcalá, Sara Carratalá, Raquel Gasque, Almudena Rubio, Laura Cubas, Luisa María Villar, Francisco Pérez-Miralles

Publikováno v: Multiple Sclerosis and Related Disorders
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
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Recent works demonstrate that patients with multiple sclerosis (pwMS) and oligoclonal M bands (OCMB) in cerebrospinal fluid (CSF) are at higher risk of conversion to secondary progressive course, suggesting a distinct pathophysiology pathway in these

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4703548462bbd1abba2872804644aec
https://pubmed.ncbi.nlm.nih.gov/36057174

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Akademický článek

Oligoclonal M bands and cervical spinal cord lesions predict early secondary progressive multiple sclerosis

Autor: Carmen Alcalá Vicente, Laura Lacruz, Francisco Gascón, Sara Carratalà, Carlos Quintanilla-Bordás, Maria T. Sanz, María Carcelén-Gadea, Javier Mallada, Joan Carreres, Laura Gabaldón Torres, Jose Andres Dominguez, Emmanuel Cañizares, Sara Gil-Perotin, Laura Cubas, Raquel Gasqué Rubio, Jéssica Castillo-Villalba, Francisco Carlos Pérez-Miralles, Bonaventura Casanova

Publikováno v: Frontiers in Neurology, Vol 13 (2022)

ObjectiveTo determine baseline cerebrospinal fluid and magnetic resonance imaging (MRI) variables at the onset of a clinically isolated syndrome (CIS) suggestive of multiple sclerosis (MS) that predict evolution to secondary progressive MS (SPMS).Met

Externí odkaz: https://doaj.org/article/6a03ba357ba243c6850fe579843e91f3

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