Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Raquel Garcia-Medina"'
Autor:
Marta Cañamero, Beatriz Jiménez, Alberto J. Schuhmacher, Isabel Hernández-Porras, Carmen Guerra, Raquel Garcia-Medina, Alba de Martino
Publikováno v:
The Journal of Pathology. 239:206-217
The Noonan syndrome (NS) is an autosomal dominant genetic disorder characterized by short stature, craniofacial dysmorphism, and congenital heart defects. A significant proportion of NS patients may also develop myeloproliferative disorders (MPDs), i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6caa92a2f1839f144b138a6215e32e40
https://doi.org/10.1002/path.4719
https://doi.org/10.1002/path.4719
Publikováno v:
Expert review of endocrinologymetabolism. 12(5)
Noonan syndrome is a RASopathy that results from activating mutations in different members of the RAS/MAPK signaling pathway. At least eleven members of this pathway have been found mutated, PTPN11 being the most frequently mutated gene affecting abo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8216ba326a654698bda27ee813ef4d17
https://pubmed.ncbi.nlm.nih.gov/30058892
https://pubmed.ncbi.nlm.nih.gov/30058892
Autor:
Grégory Bellot, Danièle Roux, Raquel Garcia-Medina, Nathalie M. Mazure, Johanna Chiche, Jacques Pouysségur, Pierre Gounon
Publikováno v:
Molecular and Cellular Biology. 29:2570-2581
While hypoxia-inducible factor (HIF) is a major actor in the cell survival response to hypoxia, HIF also is associated with cell death. Several studies implicate the HIF-induced putative BH3-only proapoptotic genes bnip3 and bnip3l in hypoxia-mediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40c07a31ea1d454a509c171249a63e2b
https://doi.org/10.1128/mcb.00166-09
https://doi.org/10.1128/mcb.00166-09
Publikováno v:
Biochemical and Biophysical Research Communications
Biochemical and Biophysical Research Communications, Elsevier, 2008, 372 (4), pp.845-9. ⟨10.1016/j.bbrc.2008.05.135⟩
Biochemical and Biophysical Research Communications, Elsevier, 2008, 372 (4), pp.845-9. ⟨10.1016/j.bbrc.2008.05.135⟩
Mammalian cells express two closely related MEK isoforms, MEK1 and MEK2, upstream of the ERK1/ERK2 MAPK module. Although genetic studies have suggested that MEK1 and MEK2 do not have overlapping functions in vivo, little is known about their specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bcc4aef1f71662779bede4d5bb9e40a
https://doi.org/10.1016/j.bbrc.2008.05.135
https://doi.org/10.1016/j.bbrc.2008.05.135
Publikováno v:
The Journal of Cell Biology
Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2007, 176 (1), pp.35-42. ⟨10.1083/jcb.200605135⟩
Journal of Cell Biology
Journal of Cell Biology, Rockefeller University Press, 2007, 176 (1), pp.35-42. ⟨10.1083/jcb.200605135⟩
Rho GTPases participate in various cellular processes, including normal and tumor cell migration. It has been reported that RhoA is targeted for degradation at the leading edge of migrating cells by the E3 ubiquitin ligase Smurf1, and that this is re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c5f336e331fdc380a94c587694d3c74
http://europepmc.org/articles/PMC2063621
http://europepmc.org/articles/PMC2063621
Autor:
Isabel, Hernández-Porras, Alberto J, Schuhmacher, Raquel, Garcia-Medina, Beatriz, Jiménez, Marta, Cañamero, Alba, de Martino, Carmen, Guerra
Publikováno v:
The Journal of pathology. 239(2)
The Noonan syndrome (NS) is an autosomal dominant genetic disorder characterized by short stature, craniofacial dysmorphism, and congenital heart defects. A significant proportion of NS patients may also develop myeloproliferative disorders (MPDs), i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::310675c5062b3ed5c41d037ac2770ab9
https://pubmed.ncbi.nlm.nih.gov/27174785
https://pubmed.ncbi.nlm.nih.gov/27174785
Autor:
Steven L. Brody, Theresa D. Joseph, Kathryn Akers, Aida Ibricevic, Thomas W. Ferkol, Seth D. Crosby, Michelle M. Farberman, Raquel Garcia-Medina, Lane L. Clarke
Publikováno v:
American journal of respiratory cell and molecular biology. 45(2)
The respiratory epithelium lining the airway relies on mucociliary clearance and a complex network of inflammatory mediators to protect the lung. Alterations in the composition and volume of the periciliary liquid layer, as occur in cystic fibrosis (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d3595f6aaf593da1e3c39f89f46bea4
https://pubmed.ncbi.nlm.nih.gov/20639462
https://pubmed.ncbi.nlm.nih.gov/20639462
Autor:
Raquel Garcia-Medina, Paul H. Schlesinger, W. Matthew Leevy, George W. Gokel, Steven L. Brody, Robert Pajewski
Publikováno v:
Chemical communications (Cambridge, England). (3)
An Ussing chamber was used to demonstrate that synthetic amphiphilic anion transporters function as chloride transporters in mammalian airway epithelial cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a902b5221fdb76adad1fe52c9e7b1f6f
https://pubmed.ncbi.nlm.nih.gov/16391750
https://pubmed.ncbi.nlm.nih.gov/16391750
Pseudomonas aeruginosa can notably cause both acute and chronic infection. While several virulence factors are implicated in the acute phase of infection, advances in understanding bacterial pathogenesis suggest that chronic P. aeruginosa infection i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f6a8c6406e4e7ecf2b25a064011df7
https://europepmc.org/articles/PMC1307054/
https://europepmc.org/articles/PMC1307054/
Autor:
Robert Pajewski, Raquel Garcia-Medina, Steven L. Brody, W. Matthew Leevy, Paul H. Schlesinger, George W. Gokel
Publikováno v:
Chemical Communications; Jan2006, Vol. 2006 Issue 3, p329-331, 3p