Výsledky vyhledávání - "Raquel Forcén"

Akademický článek

TLR2 and TLR4 Modulate Mouse Ileal Motility by the Interaction with Muscarinic and Nicotinic Receptors

Autor: Elena Layunta, Raquel Forcén, Laura Grasa

Publikováno v: Cells, Vol 11, Iss 11, p 1791 (2022)

Irritable bowel syndrome (IBS) is a chronic functional bowel disorder characterized by intestinal dysmotility. Changes in intestinal microbiota (dysbiosis) can lead to alterations in neuro-muscular functions in the gut. Toll-like receptors (TLRs) 2 a

Externí odkaz: https://doaj.org/article/c619f871373647f5b2da163e8474d4c0

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Akademický článek

NOD2 Modulates Serotonin Transporter and Interacts with TLR2 and TLR4 in Intestinal Epithelial Cells

Autor: Elena Layunta, Eva Latorre, Raquel Forcén, Laura Grasa, Marta Castro, Maykel A. Arias, Ana I. Alcalde, José Emilio Mesonero

Publikováno v: Cellular Physiology and Biochemistry, Vol 47, Iss 3, Pp 1217-1229 (2018)

Background/Aims: Serotonin (5-HT) is a chief modulator of intestinal activity. The effects of 5-HT depend on its extracellular availability, which is mainly controlled by serotonin transporter (SERT), expressed in enterocytes. On the other hand, inna

Externí odkaz: https://doaj.org/article/3e23f226af98481c8bd7f982ebf5b689

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Akademický článek

Neomycin and bacitracin reduce the intestinal permeability in mice and increase the expression of some tight-junction proteins

Autor: Rebeca Nevado, Raquel Forcén, Elena Layunta, María Divina Murillo, Laura Grasa

Publikováno v: Revista Espanola de Enfermedades Digestivas, Vol 107, Iss 11, Pp 672-676 (2015)

Background: Tight-junction (TJ) proteins regulate paracellular permeability. Gut permeability can be modulated by commensal microbiota. Manipulation of the gut microbiota with antibiotics like bacitracin and neomycin turned out to be useful for the t

Externí odkaz: https://doaj.org/article/85b6421be2c8473787038e114f6e149f

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TLR2 and TLR4 interact with sulfide system in the modulation of mouse colonic motility

Autor: Raquel Forcén, Sofia Robles, Elena Layunta, Laura Grasa, Eva Latorre, José E. Mesonero, Leticia Abecia, Ainize Peña-Cearra

Publikováno v: Zaguán. Repositorio Digital de la Universidad de Zaragoza
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Background H2S is a neuromodulator that may inhibit intestinal motility. H2S production in colon is yielded by cystathionine beta-synthase (CBS) and cystathionine gamma-lyase (CSE) enzymes and sulfate-reducing bacteria (SRB). Toll-like receptors (TLR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc06360a4dde1fe85bb7dd3adb7c649
http://zaguan.unizar.es/record/109330

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Toll-like receptors 2 and 4 exert opposite effects on the contractile response induced by serotonin in mouse colon: role of serotonin receptors

Autor: Raquel Forcén, Julián Pardo, Ana I. Alcalde, Laura Grasa, Eva Latorre, M. D. Murillo

Publikováno v: Experimental Physiology. 101:1064-1074

What is the central question of this study? The action of Toll-like receptors (TLRs) 2 and 4 on the motor response to serotonin in mouse colon has not previously been reported. What is the main finding and its importance? Toll-like receptors 2 and 4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::789930942b89d855837e981f180317f2
https://doi.org/10.1113/ep085668

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NOD1 downregulates intestinal serotonin transporter and interacts with other pattern recognition receptors

Autor: Raquel Forcén, Elena Layunta, M. A. Plaza, José E. Mesonero, Eva Latorre, Ana I. Alcalde, Laura Grasa, Maykel Arias

Publikováno v: Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname

Serotonin (5-HT) is an essential gastrointestinal modulator whose effects regulate the intestinal physiology. 5-HT effects depend on extracellular 5-HT bioavailability, which is controlled by the serotonin transporter (SERT) expressed in both the api

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::354332c571c5b2b22649b1021ed42f45
http://zaguan.unizar.es/record/75532

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NOD2 Modulates Serotonin Transporter and Interacts with TLR2 and TLR4 in Intestinal Epithelial Cells

Autor: José E. Mesonero, Marta Castro, Ana I. Alcalde, Eva Latorre, Laura Grasa, Elena Layunta, Raquel Forcén, Maykel Arias

Publikováno v: Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Cellular Physiology and Biochemistry, Vol 47, Iss 3, Pp 1217-1229 (2018)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0cae6a1c572c63c4ba220a548f531df
http://zaguan.unizar.es/record/71094

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Toll-like receptors 2 and 4 modulate the contractile response induced by serotonin in mouse ileum: analysis of the serotonin receptors involved

Autor: Raquel Forcén, Julián Pardo, M. D. Murillo, Laura Grasa, Ana I. Alcalde, Eva Latorre

Publikováno v: Neurogastroenterology & Motility. 27:1258-1266

Microbiota through toll-like receptors (TLR) may regulate gastrointestinal motility by activating neuroendocrine mechanisms. We evaluated the influence of TLR2 and TLR4 in the spontaneous contractions and serotonin (5-HT)-induced motor response in mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dca9b561ec1e5b900f374412a4d4f3f
https://doi.org/10.1111/nmo.12619

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Antibiotic-Induced Depletion of Murine Microbiota Induces Mild Inflammation and Changes in Toll-Like Receptor Patterns and Intestinal Motility

Autor: Ana I. Alcalde, Raquel Forcén, Leticia Abecia, Marta Castro, Eva Latorre, Laura Grasa, María Divina Murillo, José A. García de Jalón

Publikováno v: Microbial Ecology. 70:835-848

We examine the impact of changes in microbiota induced by antibiotics on intestinal motility, gut inflammatory response, and the function and expression of toll-like receptors (TLRs). Alterations in mice intestinal microbiota were induced by antibiot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74bacf3ab6e0f9ea928f2bdc0b5810b3
https://doi.org/10.1007/s00248-015-0613-8

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Neomycin and bacitracin reduce the intestinal permeability in mice and increase the expression of some tight-junction proteins

Autor: Laura Grasa, Raquel Forcén, Elena Layunta, María Divina Murillo, Rebeca Nevado

Publikováno v: Revista Espanola de Enfermedades Digestivas, Vol 107, Iss 11, Pp 672-676 (2015)
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Revista Española de Enfermedades Digestivas v.107 n.11 2015
SciELO España. Revistas Científicas Españolas de Ciencias de la Salud

espanolAntecedentes: las proteinas de union estrecha (UE) regulan la permeabilidad paracelular. La permeabilidad intestinal puede estar modulada por la microbiota comensal. Las manipulaciones de la microbiota intestinal con antibioticos como la bacit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f04ac2644028c38a8c0fca6a27bed8f
https://pubmed.ncbi.nlm.nih.gov/26541656

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