Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Raquel Espín Palazón"'
Autor:
Stephanie Grainger, Jenna Richter, Raquel Espín Palazón, Claire Pouget, Brianna Lonquich, Sara Wirth, Kathrin Sabine Grassme, Wiebke Herzog, Matthew R. Swift, Brant M. Weinstein, David Traver, Karl Willert
Publikováno v:
Cell Reports, Vol 17, Iss 6, Pp 1595-1606 (2016)
All mature blood cell types in the adult animal arise from hematopoietic stem and progenitor cells (HSPCs). However, the developmental cues regulating HSPC ontogeny are incompletely understood. In particular, the details surrounding a requirement for
Externí odkaz:
https://doaj.org/article/41708572565849e5a7e7ccb860acec85
Autor:
Sergio Candel, Sofía de Oliveira, Azucena López-Muñoz, Diana García-Moreno, Raquel Espín-Palazón, Sylwia D Tyrkalska, María L Cayuela, Stephen A Renshaw, Raúl Corbalán-Vélez, Inmaculada Vidal-Abarca, Huai-Jen Tsai, José Meseguer, María P Sepulcre, Victoriano Mulero
Publikováno v:
PLoS Biology, Vol 12, Iss 5, p e1001855 (2014)
TNFα overexpression has been associated with several chronic inflammatory diseases, including psoriasis, lichen planus, rheumatoid arthritis, and inflammatory bowel disease. Paradoxically, numerous studies have reported new-onset psoriasis and liche
Externí odkaz:
https://doaj.org/article/eff14dad52ab4e5ea1a64dd68ff5a645
Autor:
Liangdao Li, Xiaoyi Cheng, David Traver, Raquel Espín-Palazón, Clyde Campbell, Barbara Solchenberger, Bettina Schmid, Mark Morton, Oksana Fursova, Abbigail McCune, Elizabeth M. Snella, Debashis Sahoo
Publikováno v:
Blood Adv
Blood advances, vol 5, iss 3
Blood advances 5(3), 796-811 (2021). doi:10.1182/bloodadvances.2020003096
Blood advances, vol 5, iss 3
Blood advances 5(3), 796-811 (2021). doi:10.1182/bloodadvances.2020003096
Granulin is a pleiotropic protein involved in inflammation, wound healing, neurodegenerative disease, and tumorigenesis. These roles in human health have prompted research efforts to use granulin to treat rheumatoid arthritis and frontotemporal demen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd2f0df29b51a4c0a9c63276e35945c
https://europepmc.org/articles/PMC7876888/
https://europepmc.org/articles/PMC7876888/
Autor:
Jonatan Matalonga, Chengjian Zhao, Jan Huisken, Xin-Xin Zeng, Clyde Campbell, Joseph J. Lancman, Rashmi Mishra, P. Duc Dong, Alyssa Graves, Raquel Espín-Palazón, Jun Yin, Jiaye He, David Traver
The extent to which differentiated cells, while remaining in their native microenvironment, can be reprogrammed to assume a different identity will reveal fundamental insight into cellular plasticity and impact regenerative medicine. To investigate i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7789441f80c9cacddf069816d8dcc52
https://doi.org/10.21203/rs.3.rs-90546/v1
https://doi.org/10.21203/rs.3.rs-90546/v1
Autor:
Michel Bagnat, Raquel Espín-Palazón, Alysson R. Muotri, V. Sapp, Bart Weijts, Thomas Pietri, Ondrej Svoboda, David Traver, M. van der Vaart
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 12, Pp 1439-1451 (2017)
Mutations in MECP2 cause Rett syndrome, a severe neurological disorder with autism-like features. Duplication of MECP2 also causes severe neuropathology. Both diseases display immunological abnormalities that suggest a role for MeCP2 in controlling i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b6656eaad85a30ca7a4a9724c753ded
http://dmm.biologists.org/content/10/12/1439
http://dmm.biologists.org/content/10/12/1439
Autor:
David Traver, Raquel Espín-Palazón
Publikováno v:
Experimental Hematology. 44:519-527
The nuclear factor-κB (NF-κB) family is a crucial transcription factor group known mainly for its role in the regulation of the immune system and its response to infection in vertebrates. The signaling pathway leading to NF-κB activation and trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aca461dfe1124f39b9196fe528d0420
https://doi.org/10.1016/j.exphem.2016.03.010
https://doi.org/10.1016/j.exphem.2016.03.010
Autor:
Natasha Del Cid, Christian Mosimann, David L. Stachura, Fabienne E. Poulain, Chih-Wen Ni, Nathan D. Lawson, Martin Distel, Richard I. Dorsky, Raquel Espín-Palazón, Isao Kobayashi, Bart Weijts, Emerald Butko, Claire Pouget, David Traver, Kevin Ng, Adam D. McPherson, Wilson K. Clements
Publikováno v:
Development (Cambridge England)
The adult blood system is established by hematopoietic stem cells (HSCs), which arise during development from an endothelial-to-hematopoietic transition of cells comprising the floor of the dorsal aorta. Expression of aortic runx1 has served as an ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5021584c7c2aff686a34ebaa18879d45
https://doi.org/10.1242/dev.119180
https://doi.org/10.1242/dev.119180
Publikováno v:
Trends in cell biology. 28(1)
Hematopoietic stem cells (HSCs) have the extraordinary ability to both self-renew and generate all mature blood cell lineages. The ability to produce or expand patient-derived HSCs in vitro would greatly improve the outcome for patients with blood di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d80845efd1a3a43379a2b089bed6f78
https://pubmed.ncbi.nlm.nih.gov/28882414
https://pubmed.ncbi.nlm.nih.gov/28882414
Autor:
David Traver, Natasha Del Cid, Victoriano Mulero, David L. Stachura, José Meseguer, Diana García-Moreno, Raquel Espín-Palazón, Sergio Candel, Albert D. Kim, Clyde Campbell
Publikováno v:
Cell, vol 159, iss 5
Summary Hematopoietic stem cells (HSCs) underlie the production of blood and immune cells for the lifetime of an organism. In vertebrate embryos, HSCs arise from the unique transdifferentiation of hemogenic endothelium comprising the floor of the dor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5702ab4b7602959f82f9b4ebd33b927
https://doi.org/10.1016/j.cell.2014.10.031
https://doi.org/10.1016/j.cell.2014.10.031
Autor:
Raquel Espín-Palazón, Francisco J. Roca, Victoriano Mulero, Sylwia D. Tyrkalska, Sergio Candel, José Meseguer, Alberto Falco, Azucena López-Muñoz, A. Martinez-Lopez, Diana García-Moreno, Amparo Estepa
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 12, Iss 6, p e1005699 (2016)
PLoS Pathogens, Vol 12, Iss 6, p e1005699 (2016)
TNFα is a pleiotropic pro-inflammatory cytokine with a key role in the activation of the immune system to fight viral infections. Despite its antiviral role, a few viruses might utilize the host produced TNFα to their benefit. Some recent reports h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c813ee60430323ced7454ee5927dc0f6
https://pubmed.ncbi.nlm.nih.gov/27351838
https://pubmed.ncbi.nlm.nih.gov/27351838