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of 4
pro vyhledávání: '"Raquel E Ajalik"'
Altered TGFB1 regulated pathways promote accelerated tendon healing in the superhealer MRL/MpJ mouse
Autor:
Jacob G. Kallenbach, Margaret A. T. Freeberg, David Abplanalp, Rahul G. Alenchery, Raquel E. Ajalik, Samantha Muscat, Jacquelyn A. Myers, John M. Ashton, Alayna Loiselle, Mark R. Buckley, Andre J. van Wijnen, Hani A. Awad
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract To better understand the molecular mechanisms of tendon healing, we investigated the Murphy Roth’s Large (MRL) mouse, which is considered a model of mammalian tissue regeneration. We show that compared to C57Bl/6J (C57) mice, injured MRL t
Externí odkaz:
https://doaj.org/article/7e3b5540b6894b6b9b78695061d18e3e
Autor:
Raquel E. Ajalik, Rahul G. Alenchery, John S. Cognetti, Victor Z. Zhang, James L. McGrath, Benjamin L. Miller, Hani A. Awad
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Human Microphysiological Systems (hMPS), otherwise known as organ- and tissue-on-a-chip models, are an emerging technology with the potential to replace in vivo animal studies with in vitro models that emulate human physiology at basic levels. hMPS p
Externí odkaz:
https://doaj.org/article/7d2bad37ea37494e8463c222c9b07b70
Autor:
Thomas R. Gaborski, Zahra Allahyari, Alec T. Salminen, Renee N. Cottle, Molly C McCloskey, Shayan Gholizadeh, James L. McGrath, Raquel E Ajalik
Publikováno v:
Frontiers in Medical Technology
Inflammatory diseases and cancer metastases lack concrete pharmaceuticals for their effective treatment despite great strides in advancing our understanding of disease progression. One feature of these disease pathogeneses that remains to be fully ex
Autor:
James L. McGrath, Alec T. Salminen, Raquel E Ajalik, Angela Glading, Molly C McCloskey, Thomas R. Gaborski, Kilean Lucas, Henry H. Chung, Richard E. Waugh, Harsha Swamy, Tejas S. Khire
Publikováno v:
Cell Mol Bioeng
INTRODUCTION: The pathophysiological increase in microvascular permeability plays a well-known role in the onset and progression of diseases like sepsis and atherosclerosis. However, how interactions between neutrophils and the endothelium alter vess