Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Raquel Carvalho Gontijo"'
Autor:
Hyun Young Kim, Sadatsugu Sakane, Alvaro Eguileor, Raquel Carvalho Gontijo Weber, Wonseok Lee, Xiao Liu, Kevin Lam, Kei Ishizuka, Sara Brin Rosenthal, Karin Diggle, David A. Brenner, Tatiana Kisseleva
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 1, Pp 93-106 (2024)
Liver fibrosis of different etiologies is a serious health problem worldwide. There is no effective therapy available for liver fibrosis except the removal of the underlying cause of injury or liver transplantation. Development of liver fibrosis is c
Externí odkaz:
https://doaj.org/article/0f9a90d94d5e4bd0a2e4ea88044b0319
Autor:
Natalia A. Osna, Irina Tikhanovich, Martí Ortega-Ribera, Sebastian Mueller, Chaowen Zheng, Johannes Mueller, Siyuan Li, Sadatsugu Sakane, Raquel Carvalho Gontijo Weber, Hyun Young Kim, Wonseok Lee, Souradipta Ganguly, Yusuke Kimura, Xiao Liu, Debanjan Dhar, Karin Diggle, David A. Brenner, Tatiana Kisseleva, Neha Attal, Iain H. McKillop, Shilpa Chokshi, Ram Mahato, Karuna Rasineni, Gyongyi Szabo, Kusum K. Kharbanda
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 404 (2024)
Alcohol-associated liver disease (ALD) is a substantial cause of morbidity and mortality worldwide and represents a spectrum of liver injury beginning with hepatic steatosis (fatty liver) progressing to inflammation and culminating in cirrhosis. Mult
Externí odkaz:
https://doaj.org/article/142e2cdd280940af8c937a0c17615d54
Autor:
Xiao Liu, Kevin Lam, Huayi Zhao, Sadatsugu Sakane, Hyun Young Kim, Alvaro Eguileor, Karin Diggle, Shuai Wu, Raquel Carvalho Gontijo Weber, Pejman Soroosh, Mojgan Hosseini, Kristin Mekeel, David A. Brenner, Tatiana Kisseleva
Publikováno v:
STAR Protocols, Vol 4, Iss 3, Pp 102391- (2023)
Summary: Here, we present a protocol for isolating human hepatocytes and neural progenitor cells from normal and nonalcoholic steatohepatitis livers. We describe steps for perfusion for scaled-up liver cell isolation and optimization of chemical dige
Externí odkaz:
https://doaj.org/article/06a0220e8c7f4637ab4455a2add3b85d
Autor:
Jennifer L. Johnson, Elsa Meneses-Salas, Mahalakshmi Ramadass, Jlenia Monfregola, Farhana Rahman, Raquel Carvalho Gontijo, William B. Kiosses, Kersi Pestonjamasp, Dale Allen, Jinzhong Zhang, Douglas G. Osborne, Yanfang Peipei Zhu, Nathan Wineinger, Kasra Askari, Danni Chen, Juan Yu, Scott C. Henderson, Catherine C. Hedrick, Matilde Valeria Ursini, Sergio Grinstein, Daniel D. Billadeau, Sergio D. Catz
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-24 (2022)
Responsive exocytosis in neutrophil leukocytes involves actin depolymerisation-dependent sequential release of gelatinase granules, then strongly pro-inflammatory azurophilic granules. Here authors show that the actin nucleator protein WASH facilitat
Externí odkaz:
https://doaj.org/article/9638c498eebb49f28ed25260528bc5a9
Akademický článek
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Akademický článek
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Autor:
Ariane Barros Diniz, Maísa Mota Antunes, Viviane Aparecida de Souza Lacerda, Brenda Naemi Nakagaki, Maria Alice Freitas Lopes, Hortência Maciel de Castro-Oliveira, Matheus Silvério Mattos, Kassiana Mafra, Camila Dutra Moreira de Miranda, Karen Marques de Oliveira Costa, Mateus Eustáquio Lopes, Débora Moreira Alvarenga, Raquel Carvalho-Gontijo, Sarah Cozzer Marchesi, Debora Romualdo Lacerda, Alan Moreira de Araújo, Érika de Carvalho, Bruna Araújo David, Mônica Morais Santos, Cristiano Xavier Lima, Juliana Assis Silva Gomes, Tereza Cristina Minto Fontes Cal, Bruna Roque de Souza, Cláudia Alves Couto, Luciana Costa Faria, Paula Vieira Teixeira Vidigal, Adaliene Versiane Matos Ferreira, Sridhar Radhakrishnnan, Matthew Ricci, André Gustavo Oliveira, Rafael Machado Rezende, Gustavo Batista Menezes
Publikováno v:
JHEP Reports, Vol 2, Iss 4, Pp 100117- (2020)
Background & Aims: The precise determination of non-alcoholic fatty liver disease (NAFLD) onset is challenging. Thus, the initial hepatic responses to fat accumulation, which may be fundamental to our understanding of NAFLD evolution and clinical out
Externí odkaz:
https://doaj.org/article/7d7eb353ab4a40bd87cfa66e7e4af738
Autor:
Cuijuan Han, Raquel Carvalho-Gontijo, Lei Zhang, Vivian Zhang, Mojgan Hosseini, Kristin Mekeel, Bernd Schnabl, Rohit Loomba, Michael Karin, David A. Brenner, Tatiana Kisseleva
Publikováno v:
Semin Liver Dis
Seminars in liver disease, vol 42, iss 3
Seminars in liver disease, vol 42, iss 3
Nonalcoholic liver disease is a component of metabolic syndrome associated with obesity, insulin resistance, and hyperlipidemia. Excessive alcohol consumption may accelerate the progression of steatosis, steatohepatitis, and fibrosis. While simple st
Autor:
Sergio D. Catz, Kersi Pestonjamasp, Elsa Meneses-Salas, Catherine C. Hedrick, Raquel Carvalho Gontijo, Jenny E. Gunton, Mahalakshmi Ramadass, Gennaro Napolitano, Nadia R Zgajnar, Jennifer L. Johnson, William B. Kiosses, Yanfang Peipei Zhu, Farhana Rahman, Jinzhong Zhang, Marta Perego
Publikováno v:
Journal of Leukocyte Biology. 110:629-649
Despite the important function of neutrophils in the eradication of infections and induction of inflammation, the molecular mechanisms regulating the activation and termination of the neutrophil immune response is not well understood. Here, the funct
Autor:
Suling Zeng, Elisa Rosati, Carina Saggau, Berith Messner, Huikuan Chu, Yi Duan, Phillipp Hartmann, Yanhan Wang, Shengyun Ma, Wendy Jia Men Huang, Jihyung Lee, Sung Min Lee, Raquel Carvalho-Gontijo, Vivian Zhang, Joseph P. Hoffmann, Jay K. Kolls, Eyal Raz, David A. Brenner, Tatiana Kisseleva, Salomé LeibundGut-Landmann, Petra Bacher, Peter Stärkel, Bernd Schnabl
Publikováno v:
Cell Host & Microbe. 31:389-404.e7