Výsledky vyhledávání - "Raquel, Tobes"

Akademický článek

CD4+ tumor-infiltrating lymphocytes secreting T cell-engagers induce regression of autologous patient-derived non-small cell lung cancer xenografts

Autor: Anaïs Jiménez-Reinoso, Magdalena Molero-Abraham, Cristina Cirauqui, Belén Blanco, Eva M. Garrido-Martin, Daniel Nehme-Álvarez, Carmen Domínguez-Alonso, Ángel Ramírez-Fernández, Laura Díez-Alonso, Ángel Nuñez-Buiza, África González-Murillo, Raquel Tobes, Eduardo Pareja, Manuel Ramírez-Orellana, José Luis Rodriguez-Peralto, Irene Ferrer, Jon Zugazagoitia, Luis Paz-Ares, Luis Álvarez-Vallina

Publikováno v: OncoImmunology, Vol 13, Iss 1 (2024)

Adoptive transfer of tumor-infiltrating lymphocytes (TIL) has shown remarkable results in melanoma, but only modest clinical benefits in other cancers, even after TIL have been genetically modified to improve their tumor homing, cytotoxic potential o

Externí odkaz: https://doaj.org/article/e8672f59553649e1a19d8ee020cd28b0

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Akademický článek

A Comparison Between Recombinant Listeria GAPDH Proteins and GAPDH Encoding mRNA Conjugated to Lipids as Cross-Reactive Vaccines for Listeria, Mycobacterium, and Streptococcus

Autor: Hector Teran-Navarro, David Salcines-Cuevas, Ricardo Calderon-Gonzalez, Raquel Tobes, Jorge Calvo-Montes, Inmaculada Concepción Pérez-Del Molino Bernal, Sonsoles Yañez-Diaz, Manuel Fresno, Carmen Alvarez-Dominguez

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

Cross-reactive vaccines recognize common molecular patterns in pathogens and are able to confer broad spectrum protection against different infections. Antigens common to pathogenic bacteria that induce broad immune responses, such as the glyceraldeh

Externí odkaz: https://doaj.org/article/a41c4dc468da4c2d89cb65d45e5a75db

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Akademický článek

Epitopes for Multivalent Vaccines Against Listeria, Mycobacterium and Streptococcus spp: A Novel Role for Glyceraldehyde-3-Phosphate Dehydrogenase

Autor: Carmen Alvarez-Dominguez, David Salcines-Cuevas, Héctor Teran-Navarro, Ricardo Calderon-Gonzalez, Raquel Tobes, Isabel Garcia, Santiago Grijalvo, Alberto Paradela, Asunción Seoane, Felix J. Sangari, Manuel Fresno, Jorge Calvo-Montes, I. Concepción Pérez Del Molino Bernal, Sonsoles Yañez-Diaz

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)

The glycolytic enzyme and bacterial virulence factor of Listeria monocytogenes, the glyceraldehyde-3-phosphate dehydrogenase (GAPDH, Lmo2459), ADP-ribosylated the small GTPase, Rab5a, and blocked phagosome maturation. This inhibitory activity localiz

Externí odkaz: https://doaj.org/article/6a550dd2530d4337a3f0c90dd9cafc5d

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Akademický článek

Early OXA-48-Producing Enterobacterales Isolates Recovered in a Spanish Hospital Reveal a Complex Introduction Dominated by Sequence Type 11 (ST11) and ST405 Klebsiella pneumoniae Clones

Autor: Desirèe Gijón, Ana P. Tedim, Aránzazu Valverde, Irene Rodríguez, María-Isabel Morosini, Teresa M. Coque, Marina Manrique, Eduardo Pareja, Raquel Tobes, Patricia Ruiz-Garbajosa, Rafael Cantón

Publikováno v: mSphere, Vol 5, Iss 2 (2020)

ABSTRACT Carbapenemase-producing Enterobacterales (CPE) have become an important public health concern. In our hospital, VIM enzymes were first detected in 2005, Klebsiella pneumoniae carbapenemase (KPC) enzymes in 2009, and OXA-48 enzymes in 2012. W

Externí odkaz: https://doaj.org/article/c41266cbfcfa49ae80ccde013e8dc6ee

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Akademický článek

Pre-clinical development of Listeria-based nanovaccines as immunotherapies for solid tumours: insights from melanoma

Autor: Hector Terán-Navarro, Ricardo Calderon-Gonzalez, David Salcines-Cuevas, Isabel García, Marco Marradi, Javier Freire, Erwan Salmon, Mar Portillo-Gonzalez, Elisabet Frande-Cabanes, Almudena García-Castaño, Virginia Martinez-Callejo, Javier Gomez-Roman, Raquel Tobes, Fernando Rivera, Sonsoles Yañez-Diaz, Carmen Álvarez-Domínguez

Publikováno v: OncoImmunology, Vol 8, Iss 2 (2019)

Gold glyconanoparticles loaded with the listeriolysin O peptide 91–99 (GNP-LLO91-99), a bacterial peptide with anti-metastatic properties, are vaccine delivery platforms facilitating immune cell targeting and increasing antigen loading. Here, we pr

Externí odkaz: https://doaj.org/article/1f27fc9b9d0441b78d7ab7e29e2b2a5b

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Akademický článek

Glyceraldehyde-3-phosphate Dehydrogenase Common Peptides of Listeria monocytogenes, Mycobacterium marinum and Streptococcus pneumoniae as Universal Vaccines

Autor: David Salcines-Cuevas, Hector Terán-Navarro, Ricardo Calderón-Gonzalez, Paula Torres-Rodriguez, Raquel Tobes, Manuel Fresno, Jorge Calvo-Montes, I. Concepción Pérez Del Molino-Bernal, Sonsoles Yañez-Diaz, Carmen Alvarez-Dominguez

Publikováno v: Vaccines, Vol 9, Iss 3, p 269 (2021)

Universal vaccines can be prepared with antigens common to different pathogens. In this regard, the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a common virulence factor among pathogenic bacteria of the genera Listeria, Mycobacterium and Stre

Externí odkaz: https://doaj.org/article/24fa41b5074440188a98730e020226d7

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Akademický článek

Comparative Genomics of Field Isolates of Mycobacterium bovis and M. caprae Provides Evidence for Possible Correlates with Bacterial Viability and Virulence.

Autor: José de la Fuente, Iratxe Díez-Delgado, Marinela Contreras, Joaquín Vicente, Alejandro Cabezas-Cruz, Raquel Tobes, Marina Manrique, Vladimir López, Beatriz Romero, Javier Bezos, Lucas Dominguez, Iker A Sevilla, Joseba M Garrido, Ramón Juste, Guillermo Madico, Edward Jones-López, Christian Gortazar

Publikováno v: PLoS Neglected Tropical Diseases, Vol 9, Iss 11, p e0004232 (2015)

Mycobacteria of the Mycobacterium tuberculosis complex (MTBC) greatly affect humans and animals worldwide. The life cycle of mycobacteria is complex and the mechanisms resulting in pathogen infection and survival in host cells are not fully understoo

Externí odkaz: https://doaj.org/article/e4ed1381b0024e6db02a57fdb55a30c0

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Akademický článek

A systems biology approach to the characterization of stress response in Dermacentor reticulatus tick unfed larvae.

Autor: Margarita Villar, Marina Popara, Nieves Ayllón, Isabel G Fernández de Mera, Lourdes Mateos-Hernández, Ruth C Galindo, Marina Manrique, Raquel Tobes, José de la Fuente

Publikováno v: PLoS ONE, Vol 9, Iss 2, p e89564 (2014)

BackgroundDermacentor reticulatus (Fabricius, 1794) is distributed in Europe and Asia where it infests and transmits disease-causing pathogens to humans, pets and other domestic and wild animals. However, despite its role as a vector of emerging or r

Externí odkaz: https://doaj.org/article/d88f936389df4db68bd0d209dbefb9ff

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Glyceraldehyde-3-phosphate Dehydrogenase Common Peptides of Listeria monocytogenes, Mycobacterium marinum and Streptococcus pneumoniae as Universal Vaccines

Autor: Sonsoles Yañez-Diaz, Jorge Calvo-Montes, David Salcines-Cuevas, Carmen Alvarez-Dominguez, Paula Torres-Rodriguez, Ricardo Calderon-Gonzalez, Manuel Fresno, I. Concepción Pérez Del Molino-Bernal, Hector Teran-Navarro, Raquel Tobes

Publikováno v: Vaccines
Volume 9
Issue 3
Vaccines, Vol 9, Iss 269, p 269 (2021)
Biblos-e Archivo. Repositorio Institucional de la UAM
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Digital.CSIC. Repositorio Institucional del CSIC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8973b7f99fd03bbf7f8aa5bcb37f7af8

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