Zobrazeno 1 - 10
of 732
pro vyhledávání: '"Raquel, T."'
Autor:
Meenakshi Vij, Benjamin B. Cho, Raquel T. Yokoda, Omid Rashidipour, Melissa Umphlett, Timothy E. Richardson, Nadejda M. Tsankova
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-9 (2023)
Abstract Molecular characterization of gliomas has uncovered genomic signatures with significant impact on tumor diagnosis and prognostication. CDKN2A is a tumor suppressor gene involved in cell cycle control. Homozygous deletion of the CDKN2A/B locu
Externí odkaz:
https://doaj.org/article/c577778d01c944589b9ed8e594c91f0b
Akademický článek
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Autor:
Elisabete Teixeira, Cláudia Fernandes, Maria Bungărdean, Arnaud Da Cruz Paula, Raquel T. Lima, Rui Batista, João Vinagre, Manuel Sobrinho-Simões, Valdemar Máximo, Paula Soares
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 3, p 1522 (2024)
In a family with Familial Non-Medullary Thyroid Carcinoma (FNMTC), our investigation using Whole-Exome Sequencing (WES) uncovered a novel germline USP42 mutation [p.(Gly486Arg)]. USP42 is known for regulating p53, cell cycle arrest, and apoptosis, an
Externí odkaz:
https://doaj.org/article/996f3778682c4c51b9a5b8294d48016d
Autor:
Diana Pádua, Paula Figueira, Mariana Pinto, André Filipe Maia, Joana Peixoto, Raquel T. Lima, António Pombinho, Carlos Filipe Pereira, Raquel Almeida, Patrícia Mesquita
Publikováno v:
Cancers, Vol 15, Iss 17, p 4406 (2023)
Cancer stem cells (CSCs) are relevant therapeutic targets for cancer treatment. Still, the molecular circuits behind CSC characteristics are not fully understood. The low number of CSCs can sometimes be an obstacle to carrying out assays that explore
Externí odkaz:
https://doaj.org/article/d42f1af7759a4202ba6a3ef78622ee5f
Autor:
Joana Peixoto, Catarina Príncipe, Ana Pestana, Hugo Osório, Marta Teixeira Pinto, Hugo Prazeres, Paula Soares, Raquel T. Lima
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11285 (2023)
LRP1B remains one of the most altered genes in cancer, although its relevance in cancer biology is still unclear. Recent advances in gene editing techniques, particularly CRISPR/Cas9 systems, offer new opportunities to evaluate the function of large
Externí odkaz:
https://doaj.org/article/3b6b8ebc2c5445f7ba8409602dcf634d
Akademický článek
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Autor:
Mota, Rita1,2 (AUTHOR) rita.mota@ibmc.up.pt, Lima, Raquel T.1,3,4 (AUTHOR) rlima@ipatimup.pt, Flores, Carlos1,2,5 (AUTHOR) carloseduardof1990@gmail.com, Silva, Juliana F.1,2,6 (AUTHOR) jusilva.fm@gmail.com, Cruz, Beatriz1,2,6 (AUTHOR) beatrizscruz0798@gmail.com, Alves, Bárbara1,3,7 (AUTHOR) barbaracvalves@gmail.com, Pinto, Marta T.1,3 (AUTHOR) mtpinto@ipatimup.pt, Adessi, Alessandra8 (AUTHOR) alessandra.adessi@unifi.it, Pereira, Sara B.1,2 (AUTHOR) sarap@ibmc.up.pt, De Philippis, Roberto8 (AUTHOR) roberto.dephilippis@unifi.it, Soares, Paula1,3,4 (AUTHOR) psoares@ipatimup.pt, Tamagnini, Paula1,2,6 (AUTHOR) pmtamagn@ibmc.up.pt
Publikováno v:
Polymers (20734360). Mar2023, Vol. 15 Issue 6, p1382. 14p.
Autor:
Bárbara Alves, Joana Peixoto, Sofia Macedo, Jorge Pinheiro, Bruno Carvalho, Paula Soares, Jorge Lima, Raquel T. Lima
Publikováno v:
Cancers, Vol 15, Iss 8, p 2196 (2023)
Glioblastoma (GB) is one of the deadliest human cancers. Many GB patients do not respond to treatment, and inevitably die within a median of 15–18 months post-diagnosis, highlighting the need for reliable biomarkers to aid clinical management and t
Externí odkaz:
https://doaj.org/article/803af10b1a7545c889253b7866058163
Autor:
Rita Mota, Raquel T. Lima, Carlos Flores, Juliana F. Silva, Beatriz Cruz, Bárbara Alves, Marta T. Pinto, Alessandra Adessi, Sara B. Pereira, Roberto De Philippis, Paula Soares, Paula Tamagnini
Publikováno v:
Polymers, Vol 15, Iss 6, p 1382 (2023)
Cancer is a leading cause of death worldwide with a huge societal and economic impact. Clinically effective and less expensive anticancer agents derived from natural sources can help to overcome limitations and negative side effects of chemotherapy a
Externí odkaz:
https://doaj.org/article/c679f47775d84282ad59f68aa9b51b21
Autor:
RAQUEL T. MENEZES, THAÍS C. PEREIRA, JULIANA C. JUNQUEIRA, LUCIANE D. OLIVEIRA, LILIANA SCORZONI
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 94, Iss 2 (2022)
Abstract This study aimed to evaluate the effect of duloxetine hydrochloride (DH) on Cryptococcus neoformans. DH minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) were 18.5 µg/mL, and the combination with fluconazole
Externí odkaz:
https://doaj.org/article/0567e5f5dfb4417691239c4f69596b04