Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Rapita Sood"'
Autor:
Vijendra Sharma, Noah Cohen, Rapita Sood, Hadile Ounallah-Saad, Shunit Gal Ben-Ari, Kobi Rosenblum
Publikováno v:
Bio-Protocol, Vol 8, Iss 16 (2018)
The trace fear conditioning protocol is designed to measure hippocampal function in mice. The protocol includes a neutral conditioned stimulus (tone) and an aversive unconditioned stimulus (shock), separated in time by a trace interval. The trace int
Externí odkaz:
https://doaj.org/article/53d8b37771df441cb8e3f965b6233663
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91018 (2014)
While many signals cause upregulation of the pro-inflammatory enzyme cyclooxygenase -2 (COX-2), much less is known about mechanisms that actively downregulate its expression. We have recently shown that the prostaglandin EP1 receptor reduces the expr
Externí odkaz:
https://doaj.org/article/15cac60799084eb9afe99c267641b448
Autor:
Shimrat Mamrut, Hala Harony, Rapita Sood, Hadar Shahar-Gold, Harold Gainer, Yi-Jun Shi, Liza Barki-Harrington, Shlomo Wagner
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56869 (2013)
Oxytocin is a peptide hormone, well known for its role in labor and suckling, and most recently for its involvement in mammalian social behavior. All central and peripheral actions of oxytocin are mediated through the oxytocin receptor, which is the
Externí odkaz:
https://doaj.org/article/007594b7faf542148b50030491127c4f
Autor:
Nahum Sonenberg, Peng Wang, Zixian Li, Sunghoon Kim, Hao Huang, Jung-Hyun Choi, Haijin Xu, chutong yang, Abby Snape, Sara Bermudez, Marie-Noëlle Boivin, Nicolas Ferry, Rapita Sood, Vijendra Sharma, Joel Ryan, Morag Park, Jason Karamchandani, Bhushan Nagar
The mRNA 5’cap-binding eukaryotic translation initiation factor 4E (eIF4E) plays a major role in control of mRNA translation in health and disease. One mechanism of regulation of eIF4E activity is via phosphorylation of eIF4E by MNK kinases, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87f494f1ea764a004aa62c729edff2b0
https://doi.org/10.21203/rs.3.rs-2847028/v1
https://doi.org/10.21203/rs.3.rs-2847028/v1
Autor:
Jean-Claude Lacaille, Danning Lou, Peng Wang, Maxime Lévesque, Jeremy Y. Levett, Yelin Han, Kobi Rosenblum, Shravan Murthy, Siyan Wang, Rapita Sood, Soroush Tahmasebi, Nadeem Siddiqui, Massimo Avoli, Nahum Sonenberg, Vijendra Sharma, Shannon N Tansley, Arkady Khoutorsky, Tzu-Yu Hung
Publikováno v:
Proc Natl Acad Sci U S A
The mechanistic/mammalian target of rapamycin complex 1 (mTORC1) integrates multiple signals to regulate critical cellular processes such as mRNA translation, lipid biogenesis, and autophagy. Germline and somatic mutations in mTOR and genes upstream
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a7e16ba4a7950ced3389a0c4269010
https://pubmed.ncbi.nlm.nih.gov/33876772
https://pubmed.ncbi.nlm.nih.gov/33876772
Autor:
Mohammad J. Eslamizade, Albert Quintana, Elisenda Sanz, Karim Nader, Anthony Possemato, Matthew P. Stokes, Pavel V. Baranov, Randal J. Kaufman, Adonis Yiannakas, Maya Lalzar, Kathryn Abell, Vinh Tai Truong, Abdessattar Khlaifia, Mauro Costa-Mattioli, Shunit Gal-Ben-Ari, Arkady Khoutorsky, Azam Asgarihafshejani, Noah Cohen, Rapita Sood, Nahum Sonenberg, Vijendra Sharma, Peng Wang, Jean-Claude Lacaille, Alissa J. Nelson, Tzu-Yu Hung, Stephen J Kiniry, Fatemeh Saffarzadeh, A. Claudio Cuello, Danning Lou, Kobi Rosenblum
Publikováno v:
Signal Transduction and Targeted Therapy
An important tenet of learning and memory is the notion of a molecular switch that promotes the formation of long-term memory1–4. The regulation of proteostasis is a critical and rate-limiting step in the consolidation of new memories5–10. One of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e238da32aec1c67cb98877f0c2b39509
https://pubmed.ncbi.nlm.nih.gov/33514694
https://pubmed.ncbi.nlm.nih.gov/33514694
Autor:
Iliana Barrera, Hadile Ounallah-Saad, Hanoch Kaphzan, Rapita Sood, Efrat Edry, Vijendra Sharma, Darpan Chakraborty, Kobi Rosenblum, Mohammad Hleihil, Sailendrakumar Kolatt Chandran, Shlomo Ben Tabou de Leon
Protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) is one of four known kinases that respond to cellular stress by deactivating the eukaryotic initiation factor 2 α (eIF2α) or other signal transduction cascades. Recently, both eIF2α a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::798e3b205034e03d1a2a2a91df02ca1a
https://europepmc.org/articles/PMC6596193/
https://europepmc.org/articles/PMC6596193/
Autor:
Gilad Ritov, Almog Spector-Chotiner, Liza Barki-Harrington, Rapita Sood, Gal Richter-Levin, Boris Boltyansky
Publikováno v:
Psychoneuroendocrinology. 49:62-68
The pro-inflammatory enzyme cyclooxygenase-2 (COX-2) is regularly expressed in the hippocampal neurons, but its role in emotional trauma is not known. Here we show that a single acute stress caused by a near-drowning experience results in heightened
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14419b6e57af8f88f12c35899f9b3392
https://doi.org/10.1016/j.psyneuen.2014.06.015
https://doi.org/10.1016/j.psyneuen.2014.06.015
Publikováno v:
Biochemical and Biophysical Research Communications. 443:738-742
The cyclooxygenase (COX) enzyme isoforms COX-1 and COX-2 catalyze the main step in the generation of prostanoids that mediate major physiological functions. Whereas COX-1 is a ubiquitously expressed stable protein, COX-2 is transiently upregulated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d30fbff6db02b2e78b552611f3ad828c
https://doi.org/10.1016/j.bbrc.2013.12.038
https://doi.org/10.1016/j.bbrc.2013.12.038
Publikováno v:
The Journal of biological chemistry. 289(45)
The enzyme cyclooxygenase-2 (COX-2) plays an important role in the kidney by up-regulating the production of the vasoconstrictor hormone angiotensin II (AngII), which in turn down-regulates COX-2 expression via activation of the angiotensin II type 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c36e807fac9899caf7433dc64a2df916
https://pubmed.ncbi.nlm.nih.gov/28389577
https://pubmed.ncbi.nlm.nih.gov/28389577