Zobrazeno 1 - 10
of 218
pro vyhledávání: '"Rapinat, A."'
Autor:
Rania El‐Botty, Sophie Vacher, Juliette Mainguené, Adrien Briaux, Sabrina Ibadioune, Ahmed Dahmani, Elodie Montaudon, Fariba Nemati, Léa Huguet, Laura Sourd, Ludivine Morriset, Sophie Château‐Joubert, Thierry Dubois, Virginie Maire, Rosette Lidereau, Audrey Rapinat, David Gentien, Florence Coussy, Ivan Bièche, Elisabetta Marangoni
Publikováno v:
Molecular Oncology, Vol 17, Iss 10, Pp 2017-2028 (2023)
Triple negative breast cancers (TNBCs) represent 15–20% of all breast cancers and are associated with higher recurrence and distant metastasis rate. Standard of care for early stage TNBC is anthracyclines combined with cyclophosphamide (AC) followe
Externí odkaz:
https://doaj.org/article/544d9d964bc94114b651429060007609
Autor:
Gentien, David, Saberi-Ansari, Elnaz, Servant, Nicolas, Jolly, Ariane, de la Grange, Pierre, Némati, Fariba, Liot, Géraldine, Saule, Simon, Teissandier, Aurélie, Bourc’his, Deborah, Girard, Elodie, Wong, Jennifer, Masliah-Planchon, Julien, Narmanli, Erkan, Liu, Yuanlong, Torun, Emma, Goulancourt, Rebecca, Rodrigues, Manuel, Gaudé, Laure Villoing, Reyes, Cécile, Bazire, Matéo, Chenegros, Thomas, Henry, Emilie, Rapinat, Audrey, Bohec, Mylene, Baulande, Sylvain, M’kacher, Radhia, Jeandidier, Eric, Nicolas, André, Ciriello, Giovanni, Margueron, Raphael, Decaudin, Didier, Cassoux, Nathalie, Piperno-Neumann, Sophie, Stern, Marc-Henri, Gibcus, Johan Harmen, Dekker, Job, Heard, Edith, Roman-Roman, Sergio, Waterfall, Joshua J.
Publikováno v:
In Cell Reports 26 September 2023 42(9)
Autor:
David Gentien, Elnaz Saberi-Ansari, Nicolas Servant, Ariane Jolly, Pierre de la Grange, Fariba Némati, Géraldine Liot, Simon Saule, Aurélie Teissandier, Deborah Bourc’his, Elodie Girard, Jennifer Wong, Julien Masliah-Planchon, Erkan Narmanli, Yuanlong Liu, Emma Torun, Rebecca Goulancourt, Manuel Rodrigues, Laure Villoing Gaudé, Cécile Reyes, Matéo Bazire, Thomas Chenegros, Emilie Henry, Audrey Rapinat, Mylene Bohec, Sylvain Baulande, Radhia M’kacher, Eric Jeandidier, André Nicolas, Giovanni Ciriello, Raphael Margueron, Didier Decaudin, Nathalie Cassoux, Sophie Piperno-Neumann, Marc-Henri Stern, Johan Harmen Gibcus, Job Dekker, Edith Heard, Sergio Roman-Roman, Joshua J. Waterfall
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113132- (2023)
Summary: Uveal melanoma (UM) is a rare cancer resulting from the transformation of melanocytes in the uveal tract. Integrative analysis has identified four molecular and clinical subsets of UM. To improve our molecular understanding of UM, we perform
Externí odkaz:
https://doaj.org/article/1572404d6b2643f898a51a4a704e001b
Autor:
Shi, Ming-Jun, Fontugne, Jacqueline, Moreno-Vega, Aura, Meng, Xiang-Yu, Groeneveld, Clarice, Dufour, Florent, Kamoun, Aurélie, Viborg Lindskrog, Sia, Cabel, Luc, Krucker, Clémentine, Rapinat, Audrey, Dunois-Larde, Claire, Lepage, May-Linda, Chapeaublanc, Elodie, Levrel, Olivier, Dixon, Victoria, Lebret, Thierry, Almeida, Anna, De Reynies, Aurélien, Rochel, Natacha, Dyrskjøt, Lars, Allory, Yves, Radvanyi, François, Bernard-Pierrot, Isabelle
Publikováno v:
In European Urology January 2023 83(1):70-81
Autor:
Elodie Montaudon, Joanna Nikitorowicz-Buniak, Laura Sourd, Ludivine Morisset, Rania El Botty, Léa Huguet, Ahmed Dahmani, Pierre Painsec, Fariba Nemati, Sophie Vacher, Walid Chemlali, Julien Masliah-Planchon, Sophie Château-Joubert, Camilla Rega, Mariana Ferreira Leal, Nikiana Simigdala, Sunil Pancholi, Ricardo Ribas, André Nicolas, Didier Meseure, Anne Vincent-Salomon, Cécile Reyes, Audrey Rapinat, David Gentien, Thibaut Larcher, Mylène Bohec, Sylvain Baulande, Virginie Bernard, Didier Decaudin, Florence Coussy, Muriel Le Romancer, Guillaume Dutertre, Zakia Tariq, Paul Cottu, Keltouma Driouch, Ivan Bièche, Lesley-Ann Martin, Elisabetta Marangoni
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Identifying novel therapies for the treatment of CDK4/6 inhibitor-resistant patients is of great importance. Here, the authors demonstrate that PLK1 inhibition is a potential therapeutic target in CCND1-driven and in RB-positive Palbociclib-resistant
Externí odkaz:
https://doaj.org/article/cbbadef41cb14a1b91639138a1f60fcb
Autor:
Laurence Slembrouck, Lauren Darrigues, Cecile Laurent, Lorenza Mittempergher, Leonie JMJ Delahaye, Isabelle Vanden Bempt, Sara Vander Borght, Liesbet Vliegen, Petra Sintubin, Virginie Raynal, Mylene Bohec, Cécile Reyes, Audrey Rapinat, Céline Helsmoortel, Lynn Jongen, Griet Hoste, Patrick Neven, Hans Wildiers, Ann Smeets, Ines Nevelsteen, Kevin Punie, Els Van Nieuwenhuysen, Sileny Han, Anne Vincent Salomon, Enora Laas Faron, Timothé Cynober, David Gentien, Sylvain Baulande, Mireille HJ Snel, Anke T Witteveen, Sari Neijenhuis, Annuska M Glas, Fabien Reyal, Giuseppe Floris
Publikováno v:
Translational Oncology, Vol 12, Iss 12, Pp 1557-1565 (2019)
A previously developed and centrally validated MammaPrint® (MP) and BluePrint® (BP) targeted RNA next-generation sequencing (NGS) kit was implemented and validated in two large academic European hospitals. Additionally, breast cancer molecular subt
Externí odkaz:
https://doaj.org/article/7dd90bdd8d2b401cbc180de9d3769d13
Autor:
Linda Silina, Florent Dufour, Audrey Rapinat, Cécile Reyes, David Gentien, Fatlinda Maksut, François Radvanyi, Pierre Verrelle, Isabelle Bernard-Pierrot, Frédérique Mégnin-Chanet
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8671 (2022)
Bladder cancer is a common cancer; it is the tenth most common cancer in the world. Around one fourth of all diagnosed patients have muscle-invasive bladder cancer (MIBC), characterized by advanced tumors and which remains a lethal disease. The stand
Externí odkaz:
https://doaj.org/article/af89ec92bec648b3ac36587c58a221d6
Autor:
Hélène Neyret-Kahn, Jacqueline Fontugne, Xiang Yu Meng, Clarice S. Groeneveld, Luc Cabel, Tao Ye, Elodie Guyon, Clémentine Krucker, Florent Dufour, Elodie Chapeaublanc, Audrey Rapinat, Daniel Jeffery, Laura Tanguy, Victoria Dixon, Yann Neuzillet, Thierry Lebret, David Gentien, Irwin Davidson, Yves Allory, Isabelle Bernard-Pierrot, François Radvanyi
Publikováno v:
Oncogene. 42:1524-1542
Muscle-invasive bladder cancer (BLCA) is an aggressive disease. Consensus BLCA transcriptomic subtypes have been proposed, with two major Luminal and Basal subgroups, presenting distinct molecular and clinical characteristics. However, how these dist
Autor:
Ming-Jun Shi, Jacqueline Fontugne, Aura Moreno-Vega, Xiang-Yu Meng, Clarice Groeneveld, Florent Dufour, Aurélie Kamoun, Sia Viborg Lindskrog, Luc Cabel, Clémentine Krucker, Audrey Rapinat, Claire Dunois-Larde, May-Linda Lepage, Elodie Chapeaublanc, Olivier Levrel, Victoria Dixon, Thierry Lebret, Anna Almeida, Aurélien De Reynies, Natacha Rochel, Lars Dyrskjøt, Yves Allory, François Radvanyi, Isabelle Bernard-Pierrot
Publikováno v:
European Urology
European Urology, In press, ⟨10.1016/j.eururo.2022.09.030⟩
Shi, M J, Fontugne, J, Moreno-Vega, A, Meng, X Y, Groeneveld, C, Dufour, F, Kamoun, A, Viborg Lindskrog, S, Cabel, L, Krucker, C, Rapinat, A, Dunois-Larde, C, Lepage, M L, Chapeaublanc, E, Levrel, O, Dixon, V, Lebret, T, Almeida, A, De Reynies, A, Rochel, N, Dyrskjøt, L, Allory, Y, Radvanyi, F & Bernard-Pierrot, I 2023, ' FGFR3 Mutational Activation Can Induce Luminal-like Papillary Bladder Tumor Formation and Favors a Male Sex Bias ', European Urology, vol. 83, no. 1, pp. 70-81 . https://doi.org/10.1016/j.eururo.2022.09.030
European Urology, In press, ⟨10.1016/j.eururo.2022.09.030⟩
Shi, M J, Fontugne, J, Moreno-Vega, A, Meng, X Y, Groeneveld, C, Dufour, F, Kamoun, A, Viborg Lindskrog, S, Cabel, L, Krucker, C, Rapinat, A, Dunois-Larde, C, Lepage, M L, Chapeaublanc, E, Levrel, O, Dixon, V, Lebret, T, Almeida, A, De Reynies, A, Rochel, N, Dyrskjøt, L, Allory, Y, Radvanyi, F & Bernard-Pierrot, I 2023, ' FGFR3 Mutational Activation Can Induce Luminal-like Papillary Bladder Tumor Formation and Favors a Male Sex Bias ', European Urology, vol. 83, no. 1, pp. 70-81 . https://doi.org/10.1016/j.eururo.2022.09.030
Background: Bladder cancer (BCa) is more common in men and presents differences in molecular subtypes based on sex. Fibroblast growth factor receptor 3 (FGFR3) mutations are enriched in the luminal papillary muscle-invasive BCa (MIBC) and non-MIBC su
Autor:
Qinghe Zeng, Christophe Klein, Stefano Caruso, Pascale Maille, Narmin Ghaffari Laleh, Daniele Sommacale, Alexis Laurent, Giuliana Amaddeo, David Gentien, Audrey Rapinat, Hélène Regnault, Cécile Charpy, Cong Trung Nguyen, Christophe Tournigand, Raffaele Brustia, Jean Michel Pawlotsky, Jakob Nikolas Kather, Maria Chiara Maiuri, Nicolas Loménie, Julien Calderaro
Publikováno v:
Journal of Hepatology. 77:116-127
Patients with hepatocellular carcinoma (HCC) displaying overexpression of immune gene signatures are likely to be more sensitive to immunotherapy, however, the use of such signatures in clinical settings remains challenging. We thus aimed, using arti