Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Rapid Cancer Communication"'
Autor:
Laurent Delva, François Bailly, Camille Sauter, Marc Maynadié, Julien Guy, Benjamin Tournier, Cyril Fournier, Selim Ramla, Marie-Lorraine Chretien, Cédric Rossi, Nathalie Nadal, Laurent Martin, Bénédicte Burlet, Yannis Duffourd, Juliette Albuisson, Mary Callanan, Olivier Casasnovas, Catherine Thieblemont, Caroline Chapusot, Sylviane Ragot, Romain Aucagne, Denis Caillot, Maria Jimena Abrey-Recalde, Céline Buriller, Jean-Noël Bastie, Jessica Racine, Cyril Broccardo
Publikováno v:
Cold Spring Harbor Molecular Case Studies
Diagnosis of B-cell chronic lymphocytic leukemia (B-CLL) is usually straightforward, involving clinical, immunophenotypic (Matutes score), and (immuno)genetic analyses (to refine patient prognosis for treatment). CLL cases with atypical presentation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a889353e9e961a1aecab870a72de15e9
http://europepmc.org/articles/PMC7903887
http://europepmc.org/articles/PMC7903887
Autor:
Marilyn M. Li, Jinhua Wu, Jeffrey Schubert, Minjie Luo, Kajia Cao, Kristin Zelley, Yiming Zhong, Phillip B. Storm, Suzanne P. MacFarland, Feng Xu, Adam C. Resnick, Jessica B. Foster, Kristina A. Cole, Fumin Lin
Publikováno v:
Cold Spring Harbor Molecular Case Studies
PALB2 (partner and localizer of BRCA2) gene encodes a protein that colocalizes with BRCA2 in nuclear foci and likely permits the stable intranuclear localization and accumulation of BRCA2. PALB2 plays a critical role in maintaining genome integrity t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::487e8087fb9b88839f588197bd4c105e
http://europepmc.org/articles/PMC7476410
http://europepmc.org/articles/PMC7476410
Autor:
Steffen, Dietz, Petros, Christopoulos, Lisa, Gu, Anna-Lena, Volckmar, Volker, Endris, Zhao, Yuan, Simon J, Ogrodnik, Tomasz, Zemojtel, Claus-Peter, Heussel, Marc A, Schneider, Michael, Meister, Thomas, Muley, Martin, Reck, Matthias, Schlesner, Michael, Thomas, Albrecht, Stenzinger, Holger, Sültmann
Publikováno v:
Cold Spring Harbor Molecular Case Studies
Genetic rearrangements involving the anaplastic lymphoma kinase (ALK) gene confer sensitivity to ALK tyrosine kinase inhibitors (TKIs) and superior outcome in non-small-cell lung cancer (NSCLC). However, clinical courses vary widely, and recent studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cdf8912efd5324169103bad98cfe0376
https://pubmed.ncbi.nlm.nih.gov/31753813
https://pubmed.ncbi.nlm.nih.gov/31753813
Autor:
Heather Geiger, Scott Powers, Sadia Rahman, Minsig Choi, A. Rao Chimpiri, Vanessa Felice, Vaidehi Jobanputra, Kazimierz O. Wrzeszczynski, Minita Shah, Mayu O. Frank, Dina Manaa, Vanessa V. Michelini, Kanika Arora, Esra Dikoglu, Robert B. Darnell, Depinder Khaira
Publikováno v:
Cold Spring Harbor Molecular Case Studies
The tumor genome of a patient with advanced pancreatic cancer was sequenced to identify potential therapeutic targetable mutations after standard of care failed to produce any significant overall response. Matched tumor-normal whole-genome sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d02a2cc0ab61a7da71110dc3d9d5ed
http://europepmc.org/articles/PMC6913137
http://europepmc.org/articles/PMC6913137
Publikováno v:
Cold Spring Harbor Molecular Case Studies
Although BRAF mutations are commonly identified in many solid tumors and the response of BRAF p.V600E-positive tumors to targeted therapy is well documented, BRAF rearrangements are less frequent and are predominantly found in low-grade glioma, melan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e379912b26ce702873bcd711b1095b
http://europepmc.org/articles/PMC6549557
http://europepmc.org/articles/PMC6549557
Autor:
Matija Snuderl, Danielle Pendrick, Susan J. Hsiao, Kevin A. Roth, Benjamin Liechty, Olga Krasnozhen-Ratush, Jeffrey C. Allen, James Garvin, George Zanazzi, Mahesh Mansukhani
Publikováno v:
Cold Spring Harbor Molecular Case Studies
We report a case of a slow-growing, diffuse, infiltrating glioma in the right brainstem of a 9-yr-old boy. The tumor was negative by immunohistochemical staining for histone H3 K27M, BRAF V600E, and IDH1 R132H mutations. Fluorescence in situ hybridiz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fef868e0fe94bf4770089f063ac39306
https://doi.org/10.1101/mcs.a005660
https://doi.org/10.1101/mcs.a005660
Autor:
Christopher J, Forlenza, Yanming, Zhang, JinJuan, Yao, Ryma, Benayed, Peter, Steinherz, Kavitha, Ramaswamy, Rachel, Kessel, Mikhail, Roshal, Neerav, Shukla
Publikováno v:
Cold Spring Harbor Molecular Case Studies
Acute megakaryoblastic leukemia (AMKL) constitutes ∼5%–15% of cases of non–Down syndrome AML in children, and in the majority of cases, chimeric oncogenes resulting from recurrent gene rearrangements are identified. Based on these rearrangement
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f98719858ae5257c2d8b5f7c2c8e0a78
https://pubmed.ncbi.nlm.nih.gov/30455225
https://pubmed.ncbi.nlm.nih.gov/30455225
Autor:
Kate, Krempely, Rachid, Karam
Publikováno v:
Cold Spring Harbor Molecular Case Studies
Most truncating cadherin 1 (CDH1) pathogenic alterations confer an elevated lifetime risk of diffuse gastric cancer (DGC) and lobular breast cancer (LBC). However, transcripts containing carboxy-terminal premature stop codons have been demonstrated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bc6dddde96acddf74828280c9fff039e
https://pubmed.ncbi.nlm.nih.gov/29798843
https://pubmed.ncbi.nlm.nih.gov/29798843
Publikováno v:
Cold Spring Harbor Molecular Case Studies
Anaplastic lymphoma kinase (ALK) gene rearrangements are present in ∼5% of non-small-cell lung cancers (NSCLCs). These rearrangements occur because of a chromosomal inversion within the short arm of Chromosome 2, which results in the formation of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f48dd1ca2e35a3e252f49570a7da8d
http://europepmc.org/articles/PMC5880261
http://europepmc.org/articles/PMC5880261
Publikováno v:
Cold Spring Harbor Molecular Case Studies
An 85-yr-old woman was diagnosed with endometrial adenocarcinoma, endometrioid type. Imaging studies showed a large tumor distending the endometrial canal without evidence of local invasion or extrauterine disease. A hysterectomy was performed, follo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebb89b84305d2382ff0bc603162443c2
http://europepmc.org/articles/PMC6071573
http://europepmc.org/articles/PMC6071573