Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Raphaelle Winsky-Sommerer"'
Autor:
Raphaelle Winsky-Sommerer, Helen A. King, Valentina Iadevaia, Carla Möller-Levet, André P. Gerber
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Aging is associated with substantial physiological changes and constitutes a major risk factor for neurological disorders including dementia. Alterations in gene expression upon aging have been extensively studied; however, an in-depth characterizati
Externí odkaz:
https://doaj.org/article/22463590951c49dea3e2a8d108dcc27b
Autor:
Elizabeth Susan Maywood, Johanna Elizabeth Chesham, Raphaelle Winsky-Sommerer, Nicola Jane Smyllie, Michael Harvey Hastings
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Externí odkaz:
https://doaj.org/article/f32469d8e3354fc5941ce48231984a19
Autor:
Elizabeth Susan Maywood, Johanna Elizabeth Chesham, Raphaelle Winsky-Sommerer, Nicola Jane Smyllie, Michael Harvey Hastings
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Sleep is regulated by circadian and homeostatic processes. Whereas the suprachiasmatic nucleus (SCN) is viewed as the principal mediator of circadian control, the contributions of sub-ordinate local circadian clocks distributed across the brain are u
Externí odkaz:
https://doaj.org/article/fa730f5289a7417c944c80608d417885
Autor:
Stephane Dissel, Markus Klose, Jeff Donlea, Lijuan Cao, Denis English, Raphaelle Winsky-Sommerer, Bruno van Swinderen, Paul J. Shaw
Publikováno v:
Neurobiology of Sleep and Circadian Rhythms, Vol 2, Iss , Pp 15-26 (2017)
To test the hypothesis that sleep can reverse cognitive impairment during Alzheimer's disease, we enhanced sleep in flies either co-expressing human amyloid precursor protein and Beta-secretase (APP:BACE), or in flies expressing human tau. The ubiqui
Externí odkaz:
https://doaj.org/article/675989bb79cb445db6e7636bbe1f4110
Publikováno v:
Complexity, Vol 2019 (2019)
Symbolic dynamic analysis (SDA) methods have been applied to biomedical signals and have been proven efficient in characterising differences in the electroencephalogram (EEG) in various conditions (e.g., epilepsy, Alzheimer’s, and Parkinson’s dis
Externí odkaz:
https://doaj.org/article/507233d46e304697998c617cb4aa3d1a
Publikováno v:
Frontiers in Neural Circuits, Vol 11 (2017)
The process of neurogenesis has been demonstrated to occur throughout life in the subgranular zone (SGZ) of the hippocampal dentate gyrus of several mammals, including humans. The basal rate of adult hippocampal neurogenesis can be altered by lifesty
Externí odkaz:
https://doaj.org/article/4e766a238da24394a4acccdcb1b6a0e2
Publikováno v:
Entropy, Vol 19, Iss 12, p 673 (2017)
Specific patterns of brain activity during sleep and waking are recorded in the electroencephalogram (EEG). Time-frequency analysis methods have been widely used to analyse the EEG and identified characteristic oscillations for each vigilance state (
Externí odkaz:
https://doaj.org/article/2f98ab687ab84fb4ba1ea14721c585b0
Publikováno v:
The Journal of Neuroscience
The timing and quality of sleep-wake cycles are regulated by interacting circadian and homeostatic mechanisms. Although the suprachiasmatic nucleus (SCN) is the principal clock, circadian clocks are active across the brain and the respective sleep-re
Autor:
Paula de Oliveira, Claire Cella, Nicolas Locker, Kiran K. G. Ravindran, Agampodi Mendis, Keith Wafford, Gary Gilmour, Derk-Jan Dijk, Raphaelle Winsky-Sommerer
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 42(16)
Several cellular pathways contribute to neurodegenerative tauopathy-related disorders. Microglial activation, a major component of neuroinflammation, is an early pathologic hallmark that correlates with cognitive decline, while the unfolded protein r
Autor:
Raphaelle Winsky-Sommerer, Derk-Jan Dijk, Gary Gilmour, Paula de Oliveira, Keith A. Wafford, Sally Loomis
Publikováno v:
Neuroscience & Biobehavioral Reviews
The high prevalence of sleep disturbance in neurodegenerative and psychiatric conditions is often interpreted as evidence for both sleep's sensitivity to and causal involvement in brain pathology. Nevertheless, how and which aspects of sleep contribu