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pro vyhledávání: '"Raphaela, Bento"'
Autor:
Alexandra Burr, Patrick Erickson, Raphaela Bento, Kariman Shama, Charles Roth, Biju Parekkadan
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 368-379 (2022)
The use of adeno-associated virus (AAV) as a gene delivery vehicle for secreted peptide therapeutics can enable a new approach to durably manage chronic protein insufficiencies in patients. Yet, dosing of AAVs have been largely empirical to date. In
Externí odkaz:
https://doaj.org/article/e3e98773f95d4a3a8ef0c69fa7244bbe
Autor:
Patrick, Erickson, Aneesha, Doshi, Gunjan, Jetley, Param, Amin, Aamena, Mejevdiwala, Ashna, Patel, Raphaela, Bento, Biju, Parekkadan
Publikováno v:
Journal of Visualized Experiments.
Certain cell and tissue functions operate within the dynamic time scale of minutes to hours that are poorly resolved by conventional culture systems. This work has developed a low-cost perfusion bioreactor system that allows culture medium to be cont