Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Raphael Zinn"'
Autor:
Amanda L. Wright, Lyndsey M. Konen, Bruce G. Mockett, Gary P. Morris, Anurag Singh, Lisseth Estefania Burbano, Luke Milham, Monica Hoang, Raphael Zinn, Rose Chesworth, Richard P. Tan, Gordon A. Royle, Ian Clark, Steven Petrou, Wickliffe C. Abraham, Bryce Vissel
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-25 (2023)
Abstract Background RNA editing at the Q/R site of GluA2 occurs with ~99% efficiency in the healthy brain, so that the majority of AMPARs contain GluA2(R) instead of the exonically encoded GluA2(Q). Reduced Q/R site editing increases AMPA receptor ca
Externí odkaz:
https://doaj.org/article/b9e4dab9637d4341b888d7fc34854075
Autor:
Lyndsey M. Konen, Amanda L. Wright, Gordon A. Royle, Gary P. Morris, Benjamin K. Lau, Patrick W. Seow, Raphael Zinn, Luke T. Milham, Christopher W. Vaughan, Bryce Vissel
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-19 (2020)
Abstract Calcium (Ca2+)-permeable AMPA receptors may, in certain circumstances, contribute to normal synaptic plasticity or to neurodegeneration. AMPA receptors are Ca2+-permeable if they lack the GluA2 subunit or if GluA2 is unedited at a single nuc
Externí odkaz:
https://doaj.org/article/b5bc7dc91fc245ddbc739f87f12ef95c
Autor:
Dessislava Mladenova, Guy Barry, Lyndsey M. Konen, Sandy S. Pineda, Boris Guennewig, Lotta Avesson, Raphael Zinn, Nicole Schonrock, Maina Bitar, Nicky Jonkhout, Lauren Crumlish, Dominik C. Kaczorowski, Andrew Gong, Mark Pinese, Gloria R. Franco, Carl R. Walkley, Bryce Vissel, John S. Mattick
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
The amount of regulatory RNA encoded in the genome and the extent of RNA editing by the post-transcriptional deamination of adenosine to inosine (A-I) have increased with developmental complexity and may be an important factor in the cognitive evolut
Externí odkaz:
https://doaj.org/article/035a01122d1e4d05b15faa12ae756e8d
Autor:
Amanda L Wright, Raphael Zinn, Barbara Hohensinn, Lyndsey M Konen, Sarah B Beynon, Richard P Tan, Ian A Clark, Andrea Abdipranoto, Bryce Vissel
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e59586 (2013)
Recent human trials of treatments for Alzheimer's disease (AD) have been largely unsuccessful, raising the idea that treatment may need to be started earlier in the disease, well before cognitive symptoms appear. An early marker of AD pathology is th
Externí odkaz:
https://doaj.org/article/aa2d2c1613f94623aac0a56d33b91559
Publikováno v:
Hippocampus, vol 31, iss 7
Hippocampus
Hippocampus
The extinction of contextual fear is commonly an essential requirement for successful exposure therapy for fear disorders. However, experimental work on extinction of contextual fear is limited, and there little or no directly relevant theoretical wo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc04f6406a649cf0996d3fab5364586a
https://escholarship.org/uc/item/60j4n1tf
https://escholarship.org/uc/item/60j4n1tf
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 41, iss 18
The Journal of Neuroscience
The Journal of Neuroscience
Memories are rarely acquired under ideal conditions, rendering them vulnerable to profound omissions, errors, and ambiguities. Consistent with this, recent work using context fear conditioning has shown that memories formed after inadequate learning
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93c31559f56d9d1f3baa84b77282f7de
https://escholarship.org/uc/item/8nj131pv
https://escholarship.org/uc/item/8nj131pv
Autor:
Luke T. Milham, Raphael Zinn, Gary P. Morris, Amanda L. Wright, Benjamin K. Lau, Bryce Vissel, Patrick W. Seow, Christopher W. Vaughan, Gordon Royle, Lyndsey M. Konen
Publikováno v:
Molecular Brain, Vol 13, Iss 1, Pp 1-19 (2020)
Molecular Brain
Molecular Brain
Calcium (Ca2+)-permeable AMPA receptors may, in certain circumstances, contribute to normal synaptic plasticity or to neurodegeneration. AMPA receptors are Ca2+-permeable if they lack the GluA2 subunit or if GluA2 is unedited at a single nucleic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab88e7a3a3dd1df739e4ad03116ef755
https://doi.org/10.1186/s13041-020-0545-1
https://doi.org/10.1186/s13041-020-0545-1
Autor:
Franklin B. Krasne, Michael S. Fanselow, Raphael Zinn, Laura H. Corbit, Jessica Leake, Bryce Vissel
Publikováno v:
Current biology : CB, vol 30, iss 12
The context in which sudden fearful events occur can be poorly encoded into memory. Yet, the consequences of the resulting context-impoverished memories remain unknown. We demonstrate that restricting the time available for context encoding during co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edef726af68dfdf952c2298b697a3427
https://doi.org/10.1016/j.cub.2020.04.040
https://doi.org/10.1016/j.cub.2020.04.040
Publikováno v:
Neurobiology of Learning and Memory. 105:40-53
We focus on emerging roles for microglia in synaptic plasticity, cognition and disease. We outline evidence that ramified microglia, traditionally thought to be functionally “resting” (i.e. quiescent) in the normal brain, in fact are highly dynam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a804e3c76cb76f832cc25bbf2b192f52
https://doi.org/10.1016/j.nlm.2013.07.002
https://doi.org/10.1016/j.nlm.2013.07.002
Publikováno v:
Learningmemory (Cold Spring Harbor, N.Y.). 24(4)
Rodents require a minimal time period to explore a context prior to footshock to display plateau-level context fear at test. To investigate whether this rapid fear plateau reflects complete memory formation within that short time-frame, we used the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56101710f50a4a66aa0ab04effcec074
https://pubmed.ncbi.nlm.nih.gov/28298553
https://pubmed.ncbi.nlm.nih.gov/28298553