Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Raphael Thierry"'
Autor:
Angelo L. Grauel, Beverly Nguyen, David Ruddy, Tyler Laszewski, Stephanie Schwartz, Jonathan Chang, Julie Chen, Michelle Piquet, Marc Pelletier, Zheng Yan, Nathaniel D. Kirkpatrick, Jincheng Wu, Antoine deWeck, Markus Riester, Matt Hims, Felipe Correa Geyer, Joel Wagner, Kenzie MacIsaac, James Deeds, Rohan Diwanji, Pushpa Jayaraman, Yenyen Yu, Quincey Simmons, Shaobu Weng, Alina Raza, Brian Minie, Mirek Dostalek, Pavitra Chikkegowda, Vera Ruda, Oleg Iartchouk, Naiyan Chen, Raphael Thierry, Joseph Zhou, Iulian Pruteanu-Malinici, Claire Fabre, Jeffrey A. Engelman, Glenn Dranoff, Viviana Cremasco
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Understanding the tumor microenviroment is important before it can be exploited therapeutically. Here, the authors use single cell sequencing to study stromal cells in mouse tumors and identify a subset of interferon-licensed cancer associated fibrob
Externí odkaz:
https://doaj.org/article/55eb6b2ee746490ba919c1fb7bbcfb1d
Autor:
Zheng Yan, Raphael Thierry, Antoine deWeck, Claire Fabre, Felipe Correa Geyer, Joel Wagner, Oleg Iartchouk, Jeffrey A. Engelman, Beverly Nguyen, Rohan Diwanji, James Deeds, Julie Chen, Quincey Simmons, Naiyan Chen, Viviana Cremasco, Jonathan Chang, Joseph X. Zhou, Matt Hims, Yenyen Yu, Shaobu Weng, Pushpa Jayaraman, Stephanie Schwartz, David A. Ruddy, Michelle Piquet, Vera M. Ruda, Nathaniel D. Kirkpatrick, Pavitra Chikkegowda, Mirek Dostalek, Iulian Pruteanu-Malinici, Brian Minie, Glenn Dranoff, Markus Riester, Marc Pelletier, Alina Raza, Angelo Grauel, Kenzie MacIsaac, Jincheng Wu, Tyler Laszewski
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications
Nature Communications
Despite the increasing interest in targeting stromal elements of the tumor microenvironment, we still face tremendous challenges in developing adequate therapeutics to modify the tumor stromal landscape. A major obstacle to this is our poor understan
Autor:
Viveksagar KrishnamurthyRadhakrishna, Joshua M. Korn, Raphael Thierry, Joel Wagner, Julie Chen, Xiaoyan Li, Gaylor Boulay, David A. Ruddy, Erick Morris, Youngchul Song, Nathaniel D. Kirkpatrick, Jeffrey A. Engelman, Matthew J. Niederst, Jennifer L. Cotton, Michelle Piquet, Katja Schumacher, Kathleen Sprouffske, Peter S. Hammerman
Publikováno v:
Molecular Cancer Therapeutics. 18:A122-A122
Patients with non-small cell lung cancer (NSCLC) that is driven by an activating mutation in the epidermal growth factor receptor (EGFR) are routinely treated with tyrosine kinase inhibitors (TKI) to specifically target the activated EGFR signaling p
Literature and film generate symbolic as well as economic capital. As such, aesthetic productions exist in various contexts following contrasting rules. Which role(s) do authors and filmmakers play in positioning themselves in this conflictive relati
Autor:
Alberto Loche, Thomas Di Meglio, Joao Bacelo, Filippo M. Rijli, Andreas Lüthi, Sebastien Ducret, Jonathan P. Fadok, Raphael Thierry, Christel Genoud, Yuichi Narita, Kajari Karmakar, Taro Kitazawa
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Tonotopy is a hallmark of auditory pathways and provides the basis for sound discrimination. Little is known about the involvement of transcription factors in brainstem cochlear neurons orchestrating the tonotopic precision of pre-synaptic input. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78e9c06aa9429a3695e893dc78a2342a
http://hdl.handle.net/10261/166130
http://hdl.handle.net/10261/166130
Autor:
Michael H. Hauer, Susan M. Gasser, Jan Eglinger, Vijender Singh, Assaf Amitai, David Holcman, Raphael Thierry, Andrew Seeber, Ragna Sack, Tom Owen-Hughes, Mariya Kryzhanovska
Publikováno v:
Nature structuralmolecular biology. 24(2)
Nucleosomes are essential for proper chromatin organization and the maintenance of genome integrity. Histones are post-translationally modified and often evicted at sites of DNA breaks, facilitating the recruitment of repair factors. Whether such chr
Autor:
Antoine H.F.M. Peters, Raphael Thierry, Cheryl H. Arrowsmith, Rico Kunzmann, Mathieu Tardat, Mareike Albert, Shili Duan, Urszula Brykczynska, Lilia Kaustov, Zichuan Liu
Publikováno v:
Molecular cell
Molecular Cell
Molecular Cell, Elsevier, 2015, 58 (1), pp.157-171. ⟨10.1016/j.molcel.2015.02.013⟩
Molecular Cell
Molecular Cell, Elsevier, 2015, 58 (1), pp.157-171. ⟨10.1016/j.molcel.2015.02.013⟩
Polycomb repressive complexes PRC1 and PRC2 regulate expression of genes involved in proliferation and development. In mouse early embryos, however, canonical PRC1 localizes to paternal pericentric heterochromatin (pat-PCH), where it represses transc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44511f78d4f937ee67f13eb8a10a4583
https://edoc.unibas.ch/40114/
https://edoc.unibas.ch/40114/
SUMO ylated PRC 1 controls histone H3.3 deposition and genome integrity of embryonic heterochromatin
Autor:
Hélène Royo, Antoine H.F.M. Peters, Zichuan Liu, Mark E. Gill, Mathieu Tardat, Raphael Thierry, Evgeniy A. Ozonov
Publikováno v:
EMBO Journal
EMBO Journal, EMBO Press, 2020, 39 (13), ⟨10.15252/embj.2019103697⟩
The EMBO Journal
EMBO Journal, EMBO Press, 2020, 39 (13), ⟨10.15252/embj.2019103697⟩
The EMBO Journal
Chromatin integrity is essential for cellular homeostasis. Polycomb group proteins modulate chromatin states and transcriptionally repress developmental genes to maintain cell identity. They also repress repetitive sequences such as major satellites