Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Raphael Sangeda"'
Autor:
Siana Nkya, Liberata Mwita, Josephine Mgaya, Happiness Kumburu, Marco van Zwetselaar, Stephan Menzel, Gaston Kuzamunu Mazandu, Raphael Sangeda, Emile Chimusa, Julie Makani
Publikováno v:
BMC Medical Genetics, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background Sickle cell disease (SCD) is a blood disorder caused by a point mutation on the beta globin gene resulting in the synthesis of abnormal hemoglobin. Fetal hemoglobin (HbF) reduces disease severity, but the levels vary from one indi
Externí odkaz:
https://doaj.org/article/457c87923496460db75f9a2379c064a4
Autor:
Cherif Ben Hamda, Raphael Sangeda, Liberata Mwita, Ayton Meintjes, Siana Nkya, Sumir Panji, Nicola Mulder, Lamia Guizani-Tabbane, Alia Benkahla, Julie Makani, Kais Ghedira, H3ABioNet Consortium
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0199461 (2018)
A chronic inflammatory state to a large extent explains sickle cell disease (SCD) pathophysiology. Nonetheless, the principal dysregulated factors affecting this major pathway and their mechanisms of action still have to be fully identified and eluci
Externí odkaz:
https://doaj.org/article/6c6e7c5ba85746d2b0c642f073761d35
Autor:
Oyesola O. Ojewunmi, Titilope A. Adeyemo, Ajoke I. Oyetunji, Bassey Inyang, Afolashade Akinrindoye, Baraka S. Mkumbe, Kate Gardner, Helen Rooks, John Brewin, Hamel Patel, Sang-Hyuck Lee, Raymond Chung, Sara Rashkin, Guolian Kang, Reuben Chianumba, Raphael Sangeda, Liberata Mwita, Hezekiah Isa, Uche-Nnebe Agumadu, Rosemary Ekong, Jamilu A. Faruk, Bello Y. Jamoh, Niyi M. Adebiyi, Ismail A. Umar, Abdulaziz Hassan, Christopher Grace, Anuj Goel, Baba P.D. Inusa, Mario Falchi, Siana Nkya, Julie Makani, Hafsat R. Ahmad, Obiageli Nnodu, John Strouboulis, Stephan Menzel
BackgroundThe clinical severity of sickle cell disease (SCD) is strongly influenced by the level of fetal haemoglobin (HbF) persistent in each patient. Three major HbF loci (BCL11A,HBS1L-MYB, andXmn1-HBG2) have been reported, but a considerable hidde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eec5aa8af3810e908446c6f3dd1ab4d2
https://doi.org/10.1101/2023.05.16.23289851
https://doi.org/10.1101/2023.05.16.23289851
Autor:
Hezekiah Isa, Samuel Adegoke, Anazoeze Madu, Abdul-Aziz Hassan, Chinatu Ohiaeri, Reuben Chianumba, Biobele Brown, Emmanuel Okocha, Ngozi Ugwu, Ijeoma Diaku-Akinwumi, Titilope Adeyemo, Aisha Kuliya-Gwarzo, Livingstone Dogara, Haliru Lawal, Yohanna Tanko, Adama Ladu, Umar Kangiwa, Lilian Ekwem, Seyi Oniyangi, Tambi Wakama, Domic Umoru, Olaniyi Olanrewaju, Norah Akinola, Uche Nnebe-Agumadu, Samuel Asala, Adekunle Adekile, John Olaniyi, Raphael Sangeda, null Sickle Africa Data Coordinating Center (SADaCC), Obiageli Nnodu
Publikováno v:
Blood Cells Mol Dis
Background/objective Sickle cell disease (SCD) is a monogenic disease with multiple phenotypic expressions. Previous studies describing SCD clinical phenotypes in Nigeria were localized, with limited data, hence the need to understand how SCD varies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6623c2b3ef546aee7c5615f7e2591a52
https://doi.org/10.1016/j.bcmd.2020.102438
https://doi.org/10.1016/j.bcmd.2020.102438
Autor:
Matthias, Assel, David, van de Vijver, Pieter, Libin, Kristof, Theys, Daniel, Harezlak, Breanndán, O Nualláin, Piotr, Nowakowski, Marian, Bubak, Anne-Mieke, Vandamme, Stijn, Imbrechts, Raphael, Sangeda, Tao, Jiang, Dineke, Frentz, Peter, Sloot
Publikováno v:
Studies in health technology and informatics. 147
In order to perform clinical investigations on integrated biomedical data sets and to predict virological and epidemiological outcome, medical experts require an IT-based collaborative environment that provides them a user-friendly space for building
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d7f8422cd61b7281fbe9d7a852e6909b
https://pubmed.ncbi.nlm.nih.gov/19593044
https://pubmed.ncbi.nlm.nih.gov/19593044