Zobrazeno 1 - 10
of 14 168
pro vyhledávání: '"Raphael R"'
Publikováno v:
Journal of Inflammation Research, Vol Volume 17, Pp 4865-4879 (2024)
Ben Li,1– 4,* Farah Shaikh,2,* Abdelrahman Zamzam,2 Ravel Raphael,2 Muzammil H Syed,2 Houssam K Younes,5 Rawand Abdin,6 Mohammad Qadura1– 3,7 1Department of Surgery, University of Toronto, Toronto, Ontario, Canada; 2Division of Vascular S
Externí odkaz:
https://doaj.org/article/86f1ca81863644ec9c2db2bd253bc43a
Publikováno v:
JDS Communications, Vol 5, Iss 4, Pp 310-316 (2024)
Respiratory rate (RR) is commonly employed for identifying animals experiencing heat-stress conditions and respiratory diseases. Recent advancements in computer vision algorithms have enabled the estimation of the RR in dairy cows through image-based
Externí odkaz:
https://doaj.org/article/16065071e7834a27946ae1f9ef071963
Autor:
Dominika Kanschik, Jafer Haschemi, Houtan Heidari, Kathrin Klein, Shazia Afzal, Oliver Maier, Kerstin Piayda, Stephan Binneboesssel, Goeksen Oezaslan, Raphael R. Bruno, Gerald Antoch, Artur Lichtenberg, Felix Fleissner, Maximillian Scherner, Malte Kelm, Tobias Zeus, Christian Jung
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 15 (2024)
Background Detailed visualization and precise measurements of aortic valve dimensions are critical for the success of transcatheter aortic valve implantation and for the prevention of complications. Currently, multislice computed tomography is the go
Externí odkaz:
https://doaj.org/article/f02fdbf0a24d48549c38419e1a418a07
Autor:
Mette C. Dekkers, Joost M. Lambooij, Xudong Pu, Raphael R. Fagundes, Agustin Enciso-Martinez, Kim Kats, Ben N. G. Giepmans, Bruno Guigas, Arnaud Zaldumbide
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ObjectiveBeta cell destruction in type 1 diabetes (T1D) results from the combined effect of inflammation and recurrent autoimmunity. In recent years, the role played by beta cells in the development of T1D has evolved from passive victims of the immu
Externí odkaz:
https://doaj.org/article/2b3c885eac0a4db1b569f2a73fe0eacb
Decrypting lysine deacetylase inhibitor action and protein modifications by dose-resolved proteomics
Autor:
Yun-Chien Chang, Christian Gnann, Raphael R. Steimbach, Florian P. Bayer, Severin Lechner, Amirhossein Sakhteman, Miriam Abele, Jana Zecha, Jakob Trendel, Matthew The, Emma Lundberg, Aubry K. Miller, Bernhard Kuster
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114272- (2024)
Summary: Lysine deacetylase inhibitors (KDACis) are approved drugs for cutaneous T cell lymphoma (CTCL), peripheral T cell lymphoma (PTCL), and multiple myeloma, but many aspects of their cellular mechanism of action (MoA) and substantial toxicity ar
Externí odkaz:
https://doaj.org/article/675013f87a3d4a3d988e68db6e78c7c5
Autor:
Jakob Wollborn, Zilu Zhang, Julie Gaa, Moritz Gentner, Christian Hausmann, Felix Saenger, Karina Weise, Samuel Justice, Jean-Luca Funk, Hans Felix Staehle, Marie Thomas, Raphael R. Bruno, Babak Saravi, Jan O. Friess, Markus Marx, Hartmut Buerkle, Georg Trummer, Jochen D. Muehlschlegel, Daniel Reker, Ulrich Goebel, Felix Ulbrich
Publikováno v:
Annals of Intensive Care, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Background Patients undergoing cardiac surgery are prone to numerous complications. Increased vascular permeability may be associated with morbidity and mortality due to hemodynamic instability, fluid overload, and edema formation. We hypoth
Externí odkaz:
https://doaj.org/article/6dc9da8005344cc49ff81436809c0948
Autor:
Severin Lechner, Raphael R. Steimbach, Longlong Wang, Marshall L. Deline, Yun-Chien Chang, Tobias Fromme, Martin Klingenspor, Patrick Matthias, Aubry K. Miller, Guillaume Médard, Bernhard Kuster
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Lipoic acid is an essential enzyme cofactor in central metabolic pathways. Due to its claimed antioxidant properties, racemic (R/S)-lipoic acid is used as a food supplement but is also investigated as a pharmaceutical in over 180 clinical tr
Externí odkaz:
https://doaj.org/article/ed182da2a1c645a1ab1612e13877687d
Autor:
Raphael R. Fagundes, Gabriela Bravo-Ruiseco, Shixian Hu, Sarah J. Kierans, Rinse K. Weersma, Cormac T. Taylor, Gerard Dijkstra, Hermie J. M. Harmsen, Klaas Nico Faber
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
IntroductionIntestinal epithelial cells produce interleukin-18 (IL-18), a key factor in promoting epithelial barrier integrity. Here, we analyzed the potential role of gut bacteria and the hypoxia-inducible factor 1α (HIF1α) pathway in regulating m
Externí odkaz:
https://doaj.org/article/5f37fa2f42fd405ca3fe8ff2670a47dc
Autor:
Bruno Caramelli, Pai Ching Yu, Francisco A. M. Cardozo, Iuri R. Magalhães, Raphael R. Spera, Daniel K. Amado, Maria C. Escalante-Rojas, Danielle M. Gualandro, Daniela Calderaro, Caio A. M. Tavares, Flavio A. Borges-Junior, Adriana F. Pastana, Mariana G. Matheus, Sonia M. D. Brucki, Ana Carolina O. Rodrigues, Ricardo Nitrini, Paulo Caramelli
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-10 (2022)
Abstract Background Observational studies support a role for oral anticoagulation to reduce the risk of dementia in atrial fibrillation patients, but conclusive data are lacking. Since dabigatran offers a more stable anticoagulation, we hypothesized
Externí odkaz:
https://doaj.org/article/a06f1851e2eb4f01b947f291aa0dfeac
Autor:
ELIANE M. SANTOS SOBRINHO, HÉRCULES O. SANTOS, ERNANE R. MARTINS, FRANCINE SOUZA ALVES DA FONSECA, LUCYANA C. FARIAS, CHARLES M. AGUILAR, ULISSES A. PEREIRA, NILSON NICOLAU JUNIOR, MATHEUS S. GOMES, CINTYA N. DE SOUZA, JOÃO MATHEUS A. RAVNJAK, RAPHAEL R. PORTO, ANNA CHRISTINA DE ALMEIDA
Publikováno v:
Anais da Academia Brasileira de Ciências, Vol 94, Iss suppl 3 (2022)
Abstract This study aimed to verify the action of bioactive compounds from Brazilian plants on the leader genes involved in the SARS-CoV-2 pathway. The main human genes involved were identified in GeneCards and UNIPROT platforms, and an interaction n
Externí odkaz:
https://doaj.org/article/6f0d2f7da70d4e0b9fff233dce4f2d57