Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Raphael Paus"'
Autor:
Peter Toson, Diogo G. Lopes, Raphael Paus, Ashish Kumar, Jeroen Geens, Sandy Stibale, Julian Quodbach, Peter Kleinebudde, Wen-Kai Hsiao, Johannes Khinast
Publikováno v:
International Journal of Pharmaceutics: X, Vol 1, Iss , Pp - (2019)
This work presents a new model based approach to process design and scale-up within the same equipment of a roller compaction process. The prediction of the operating space is not performed fully in-silico, but uses low-throughput experiments as inpu
Externí odkaz:
https://doaj.org/article/dfd576819c1341e6aa81340b5843143e
Publikováno v:
Chemical Engineering Journal. 444:136678
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40bbea553e091286967a329e1c8aea4a
https://doi.org/10.1016/j.cej.2022.136678
https://doi.org/10.1016/j.cej.2022.136678
Publikováno v:
Chemical Engineering Research and Design. 121:22-31
In this work, amorphous paracetamol/Eudragit ® formulations for four Eudragit ® (polymeric excipients) were prepared by spray drying technique. The simultaneous dissolution kinetics of paracetamol and Eudragit ® from these formulations were measur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::accfd11e77c725f2de54e11dc6dd1ca2
https://doi.org/10.1016/j.cherd.2017.03.007
https://doi.org/10.1016/j.cherd.2017.03.007
Autor:
Jeroen Geens, Ashish Kumar, Sandy Stibale, Peter Toson, Johannes Khinast, Raphael Paus, Wen-Kai Hsiao, Julian Quodbach, Peter Kleinebudde, Diogo G. Lopes
Publikováno v:
INTERNATIONAL JOURNAL OF PHARMACEUTICS-X
International Journal of Pharmaceutics: X, Vol 1, Iss, Pp-(2019)
International Journal of Pharmaceutics: X
International Journal of Pharmaceutics: X, Vol 1, Iss, Pp-(2019)
International Journal of Pharmaceutics: X
Graphical abstract
This work presents a new model based approach to process design and scale-up within the same equipment of a roller compaction process. The prediction of the operating space is not performed fully in-silico, but uses low-throug
This work presents a new model based approach to process design and scale-up within the same equipment of a roller compaction process. The prediction of the operating space is not performed fully in-silico, but uses low-throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7b2396154c047e04c3a679953c1f9d
https://biblio.ugent.be/publication/8730425
https://biblio.ugent.be/publication/8730425
Publikováno v:
AIChE Journal. 62:4055-4065
The release kinetics of indomethacin (IND) and hydrochlorothiazide (HCT) from drug/PLGA formulations with different copolymer composition and molecular weight of PLGA were measured in vitro by using a rotating disk system (USP II). The release mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c06b378f35d74e93c2e93d3260cb4bf7
https://doi.org/10.1002/aic.15282
https://doi.org/10.1002/aic.15282
Autor:
Raphael Paus, Yuanhui Ji
Publikováno v:
Chemical Engineering Science. 145:10-20
In this work, the dissolution profiles of different crystalline active pharmaceutical ingredients (APIs), which show a diverse water solubility (paracetamol>hydrochlorothiazide>trimethoprim>naproxen>indomethacin>cinnarizine) were measured in water at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f46706d5f34794bfaab5ed54739ae39
https://doi.org/10.1016/j.ces.2016.01.040
https://doi.org/10.1016/j.ces.2016.01.040
Publikováno v:
Journal of Chemical & Engineering Data. 60:2256-2261
The solubility of cinnarizine has been investigated in acetonitrile, butyl acetate, 1-butanol, 2-propanol, and water in a temperature range from 288.15 K to 313.15 K. During crystallization from these solvents two different crystal morphologies of ci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43f32600a41e2bf1db50c990f2fb696b
https://doi.org/10.1021/acs.jced.5b00075
https://doi.org/10.1021/acs.jced.5b00075
Publikováno v:
Industrial & Engineering Chemistry Research. 54:731-742
In this work, a two-step chemical-potential-gradient model based on nonequilibrium thermodynamic principles was developed to investigate the dissolution mechanism of crystalline active pharmaceutical ingredients (APIs). The perturbed-chain statistica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::412dd0f52889ce268955bccb6eae8b8d
https://doi.org/10.1021/ie503939w
https://doi.org/10.1021/ie503939w
Autor:
Peter Walzel, Axel Mescher, Eva Maria Littringer, Hartmuth Schroettner, Nora Anne Urbanetz, Raphael Paus
Publikováno v:
Powder Technology. 239:162-174
As the morphology of spray dried aqueous mannitol solutions is strongly influenced by the scale of the used spray dryer or more correctly by the droplet size generated in the spray dryer the purpose of this work is to carefully study and compare the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76bac1250be0e18f84bbbbc7023ea9d8
https://doi.org/10.1016/j.powtec.2013.01.065
https://doi.org/10.1016/j.powtec.2013.01.065
Publikováno v:
Chemie Ingenieur Technik. 84:154-159
Der Einfluss der Zerstaubungsmethode auf die Homogenitat spruhgetrockneter Produkte wird diskutiert. Eng verteilte Tropfengrosen sind die Voraussetzung fur einheitliche Trocknungsverlaufe und Morphologien der Einzelpartikel. Am Beispiel der Spruhtroc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8702b774b38566eb8d5c21cbf2198895
https://doi.org/10.1002/cite.201100155
https://doi.org/10.1002/cite.201100155