Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Raphael M Bendriem"'
Publikováno v:
eLife, Vol 8 (2019)
Occludin (OCLN) mutations cause human microcephaly and cortical malformation. A tight junction component thought absent in neuroepithelium after neural tube closure, OCLN isoform-specific expression extends into corticogenesis. Full-length and trunca
Externí odkaz:
https://doaj.org/article/de08fbcff580431da90e40cbe25343bc
Publikováno v:
Journal of Biomedical Science, Vol 24, Iss 1, Pp 1-12 (2017)
Abstract Three-dimensional (3D) brain organoids derived from human pluripotent stem cells (hPSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), appear to recapitulate the brain’s 3D cytoarchitectural arrangement
Externí odkaz:
https://doaj.org/article/2b5c0d8f33754942811e6aa260bfc883
Publikováno v:
Neurobiology of Stress, Vol 10, Iss , Pp - (2019)
Prenatal substance exposure is a growing public health concern worldwide. Although the opioid crisis remains one of the most prevalent addiction problems in our society, abuse of cocaine, methamphetamines, and other illicit drugs, particularly amongs
Externí odkaz:
https://doaj.org/article/741398f458784aa6a730d0fce740ad62
Autor:
Chun-Ting Lee, Raphael M. Bendriem, Abigail A. Kindberg, Lila T. Worden, Melanie P. Williams, Tomas Drgon, Barbara S. Mallon, Brandon K. Harvey, Christopher T. Richie, Rebecca S. Hamilton, Jia Chen, Stacie L. Errico, Shang-Yi A. Tsai, George R. Uhl, William J. Freed
Publikováno v:
Cell Reports, Vol 10, Iss 4, Pp 616-632 (2015)
Human pluripotent stem cell (hPSC) lines exhibit repeated patterns of genetic variation, which can alter in vitro properties as well as suitability for clinical use. We examined associations between copy-number variations (CNVs) on chromosome 17 and
Externí odkaz:
https://doaj.org/article/270a8a7e6811439e9276a9c0231e0f07
Autor:
Abigail A. Kindberg, Raphael M. Bendriem, Charles E. Spivak, Jia Chen, Annelie Handreck, Carl R. Lupica, Jinny Liu, William J. Freed, Chun-Ting Lee
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 12, Pp 1397-1405 (2014)
Neocortical development involves ordered specification of forebrain cortical progenitors to various neuronal subtypes, ultimately forming the layered cortical structure. Modeling of this process using human pluripotent stem cells (hPSCs) would enable
Externí odkaz:
https://doaj.org/article/f1e077aab17c47938a76f57a7c47904a
Publikováno v:
Restorative neurology and neuroscience. 39(4)
Background: Motor and cognitive decline as part of the normal aging process is linked to alterations in synaptic plasticity and reduction of adult neurogenesis in the dorsal striatum. Neuroinflammation, particularly in the form of microglial activati
Publikováno v:
Journal of Biomedical Science, Vol 24, Iss 1, Pp 1-12 (2017)
Journal of Biomedical Science
Journal of Biomedical Science
Three-dimensional (3D) brain organoids derived from human pluripotent stem cells (hPSCs), including embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), appear to recapitulate the brain’s 3D cytoarchitectural arrangement and prov
Autor:
Raphael M Bendriem, M. Elizabeth Ross
Publikováno v:
Neuron
Brain function requires connecting neuronal networks to empower movement, sensation, behavior, and cognition. Studies published early this year provide evidence that in humans, Netrin receptor, Deleted in Colorectal Cancer (DCC), is a master regulato
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
Occludin(OCLN) mutations cause human microcephaly and cortical malformation. A tight junction component thought absent in neuroepithelium after neural tube closure, OCLN isoform-specific expression extends into corticogenesis. Full-length and truncat