Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Raphael Lis"'
Autor:
Isidora Stankovic, Michael Notaras, Paul Wolujewicz, Tyler Lu, Raphael Lis, M. Elizabeth Ross, Dilek Colak
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Schizophrenia (SCZ) is a complex neurodevelopmental disorder characterized by the manifestation of psychiatric symptoms in early adulthood. While many research avenues into the origins of SCZ during brain development have been explored, the
Externí odkaz:
https://doaj.org/article/035ae9ad1c6b4a3592e4af5190b5ac93
Autor:
David M. Barry, Elizabeth A. McMillan, Balvir Kunar, Raphael Lis, Tuo Zhang, Tyler Lu, Edward Daniel, Masataka Yokoyama, Jesus M. Gomez-Salinero, Angara Sureshbabu, Ondine Cleaver, Annarita Di Lorenzo, Mary E. Choi, Jenny Xiang, David Redmond, Sina Y. Rabbany, Thangamani Muthukumar, Shahin Rafii
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The kidney is vascularized with highly specialized and zonated endothelial cells that are essential for its filtration function. Here, Barry et al. provide a single-cell RNA sequencing analysis of the kidney vasculature that highlights its transcript
Externí odkaz:
https://doaj.org/article/89ca827692df403aa71f8398b5ac7748
Autor:
Jessica Hoarau-Véchot, Cyril Touboul, Najeeb Halabi, Morgane Blot-Dupin, Raphael Lis, Charbel Abi Khalil, Shahin Rafii, Arash Rafii, Jennifer Pasquier
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-11 (2019)
Abstract Background One main challenge in ovarian cancer rests on the presence of a relapse and an important metastatic disease, despite extensive surgical debulking and chemotherapy. The difficulty in containing metastatic cancer is partly due to th
Externí odkaz:
https://doaj.org/article/3d56a8a004d8412d8cab9f1d63d6cf73
Autor:
Sadaf Amin, Brandoch Cook, Ting Zhou, Zaniar Ghazizadeh, Raphael Lis, Tuo Zhang, Mona Khalaj, Miguel Crespo, Manuradhi Perera, Jenny Zhaoying Xiang, Zengrong Zhu, Mark Tomishima, Chengyang Liu, Ali Naji, Todd Evans, Danwei Huangfu, Shuibing Chen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
GLIS3 mutations are associated with type 1, type 2, and neonatal diabetes. Here, the authors generate mono-hormonal glucose-responding pancreatic β-like cells in vitro and through a screen identify a drug that rescues pancreatic β-like cell death i
Externí odkaz:
https://doaj.org/article/c14e49f0fd174b1ebce0f8854fb56b94
Autor:
Jennifer Pasquier, Marie Gosset, Caroline Geyl, Jessica Hoarau-Véchot, Audrey Chevrot, Marc Pocard, Massoud Mirshahi, Raphael Lis, Arash Rafii, Cyril Touboul
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-14 (2018)
Abstract Background Minimal residual disease is the main issue of advanced ovarian cancer treatment. According to the literature and previous results, we hypothesized that Mesenchymal Stromal Cells (MSC) could support this minimal residual disease by
Externí odkaz:
https://doaj.org/article/519f9acd55434623844a7719a97fc606
Autor:
Alon Kedem, Anate Aelion-Brauer, Peipei Guo, Duancheng Wen, Bi-Sen Ding, Raphael Lis, Du Cheng, Vladislav M. Sandler, Shahin Rafii, Zev Rosenwaks
Publikováno v:
Journal of Ovarian Research, Vol 10, Iss 1, Pp 1-12 (2017)
Abstract Background New data suggests that endothelial cells (ECs) elaborate essential “angiocrine factors”. The aim of this study is to investigate the role of activated ovarian endothelial cells in early in-vitro follicular development. Methods
Externí odkaz:
https://doaj.org/article/427d4957894c473c94f961791de3f593
Autor:
William Schachterle, Chaitanya R. Badwe, Brisa Palikuqi, Balvir Kunar, Michael Ginsberg, Raphael Lis, Masataka Yokoyama, Olivier Elemento, Joseph M. Scandura, Shahin Rafii
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Endothelial cells (ECs) are promising strategies to treat vasculopathies but little is known about the factors that sustain EC identity and govern functional integration into vasculature after transplantation. Here the authors show that Ets factors a
Externí odkaz:
https://doaj.org/article/11bf9229b67e48d3aa00b6943deb460c
Autor:
David Reichman, Limor Man, Laura Park, Raphael Lis, Jeannine Gerhardt, Zev Rosenwaks, Daylon James
Publikováno v:
Stem Cell Research, Vol 17, Iss 2, Pp 391-400 (2016)
During development, endothelial cells (EC) display tissue-specific attributes that are unique to each vascular bed, as well as generic signaling mechanisms that are broadly applied to create a patent circulatory system. We have previously utilized hu
Externí odkaz:
https://doaj.org/article/64bb1fbe3e42417395b4468bbf1fa3da
Autor:
Raphael Lis, Cyril Touboul, Christophe M Raynaud, Joel A Malek, Karsten Suhre, Massoud Mirshahi, Arash Rafii
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e38340 (2012)
Tumor microenvironment is an important actor of ovarian cancer progression but the relations between mesenchymal cells and ovarian cancer cells remain unclear. The objective of this study was to determine the ovarian cancer cells' biological modifica
Externí odkaz:
https://doaj.org/article/c8c896d684f541009dd492db51163989
Autor:
Joel A Malek, Eliane Mery, Yasmin A Mahmoud, Eman K Al-Azwani, Laurence Roger, Ruby Huang, Eva Jouve, Raphael Lis, Jean-Paul Thiery, Denis Querleu, Arash Rafii
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28561 (2011)
Ovarian cancer is the most deadly gynecological cancer. The high rate of mortality is due to the large tumor burden with extensive metastatic lesion of the abdominal cavity. Despite initial chemosensitivity and improved surgical procedures, abdominal
Externí odkaz:
https://doaj.org/article/1b35a7481b5f4ba18297acac980e14f6