Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Raphael Guerois"'
Autor:
Célia Caillet-Saguy, Angelo Toto, Raphael Guerois, Pierre Maisonneuve, Eva di Silvio, Kristi Sawyer, Stefano Gianni, Nicolas Wolff
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Human protein tyrosine phosphatase non-receptor type 4 (PTPN4) has been shown to prevent cell death. The active form of human PTPN4 consists of two globular domains, a PDZ (PSD-95/Dlg/ZO-1) domain and a phosphatase domain, tethered by a flex
Externí odkaz:
https://doaj.org/article/cee468f5e6294dbb87c0a2a532e72493
Autor:
Joiselle Blanche Fernandes, Marine Duhamel, Mathilde Seguéla-Arnaud, Nicole Froger, Chloé Girard, Sandrine Choinard, Victor Solier, Nancy De Winne, Geert De Jaeger, Kris Gevaert, Philippe Andrey, Mathilde Grelon, Raphael Guerois, Rajeev Kumar, Raphaël Mercier
Publikováno v:
PLoS Genetics, Vol 14, Iss 4, p e1007317 (2018)
Homologous recombination is central to repair DNA double-strand breaks, either accidently arising in mitotic cells or in a programed manner at meiosis. Crossovers resulting from the repair of meiotic breaks are essential for proper chromosome segrega
Externí odkaz:
https://doaj.org/article/d06d1133fd2e4a3f955b7577d5a3c0f4
The revolution brought about by AlphaFold2 and the performance of AlphaFold2-Multimer open promising perspectives to unravel the complexity of protein-protein interaction networks. Nevertheless, the analysis of interaction networks obtained from prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2711e3ba115cbdaf0a18c242031dddb0
https://doi.org/10.1101/2023.05.25.542287
https://doi.org/10.1101/2023.05.25.542287
Autor:
Hugo Schweke, Qifang Xu, Gerardo Tauriello, Lorenzo Pantolini, Torsten Schwede, Frédéric Cazals, Alix Lhéritier, Juan Fernandez-Recio, Luis Ángel Rodríguez-Lumbreras, Ora Schueler-Furman, Julia K. Varga, Brian Jiménez-García, Manon F. Réau, Alexandre Bonvin, Castrense Savojardo, Pier-Luigi Martelli, Rita Casadio, Jérôme Tubiana, Haim Wolfson, Romina Oliva, Didier Barradas-Bautista, Tiziana Ricciardelli, Luigi Cavallo, Česlovas Venclovas, Kliment Olechnovič, Raphael Guerois, Jessica Andreani, Juliette Martin, Xiao Wang, Daisuke Kihara, Anthony Marchand, Bruno Correia, Xiaoqin Zou, Sucharita Dey, Roland Dunbrack, Emmanuel Levy, Shoshana Wodak
Reliably scoring and ranking candidate models of protein complexes and assigning their oligomeric state from the structure of the crystal lattice represent outstanding challenges. A community-wide effort was launched to tackle these challenges. The l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adaf2d977a6fae24f92d44626aa47f9a
https://doi.org/10.22541/au.167569565.51141128/v1
https://doi.org/10.22541/au.167569565.51141128/v1
Autor:
Dipesh Kumar Singh, Rigel Salinas Gamboa, Avinash Kumar Singh, Birgit Walkemeier, Jelle Van Leene, Geert De Jaeger, Imran Siddiqi, Raphael Guerois, Wayne Crismani, Raphael Mercier
Publikováno v:
NUCLEIC ACIDS RESEARCH
At meiosis, programmed meiotic DNA double-strand breaks are repaired via homologous recombination, resulting in crossovers (COs). From a large excess of DNA double-strand breaks that are formed, only a small proportion gets converted into COs because
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50582b4756336830be405ee1db3c0e61
https://biblio.ugent.be/publication/01GQHH38CGMG3RW3QEMW8Q2B41
https://biblio.ugent.be/publication/01GQHH38CGMG3RW3QEMW8Q2B41
Autor:
Dipesh Kumar Singh, Rigel Salinas Gamboa, Avinash Kumar Singh, Birgit Walkemeir, Jelle Van Leene, Geert De Jaeger, Imran Siddiqi, Raphael Guerois, Wayne Crismani, Raphael Mercier
At meiosis, programmed meiotic DNA double-strand breaks are repaired via homologous recombination, resulting in crossovers (COs). From a large excess of DNA double-strand breaks that are formed, only a small proportion gets converted into COs because
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ebc0cb185c3c50d0bef7249a657c193
https://doi.org/10.1101/2022.07.05.498687
https://doi.org/10.1101/2022.07.05.498687
Publikováno v:
Bioinformatics
Bioinformatics, 2021, ⟨10.1093/bioinformatics/btab254⟩
Bioinformatics, Oxford University Press (OUP), 2021, ⟨10.1093/bioinformatics/btab254⟩
Bioinformatics, 2021, ⟨10.1093/bioinformatics/btab254⟩
Bioinformatics, Oxford University Press (OUP), 2021, ⟨10.1093/bioinformatics/btab254⟩
Motivation The crucial role of protein interactions and the difficulty in characterizing them experimentally strongly motivates the development of computational approaches for structural prediction. Even when protein–protein docking samples correct
Autor:
Ananya Acharya, Hélène Bret, Jen-Wei Huang, Martin Mütze, Martin Göse, Vera Maria Kissling, Ralf Seidel, Alberto Ciccia, Raphaël Guérois, Petr Cejka
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract HROB promotes the MCM8-9 helicase in DNA damage response. To understand how HROB activates MCM8-9, we defined their interaction interface. We showed that HROB makes important yet transient contacts with both MCM8 and MCM9, and binds the MCM8
Externí odkaz:
https://doaj.org/article/f907eefa14ff4cc6a2a975c93ecb0f6b
Autor:
Josua Zönnchen, Johannes Gantner, Dmitry Lapin, Karen Barthel, Lennart Eschen-Lippold, Stefan Zantop, Carola Kretschmer, Jane E. Parker, Raphael Guerois, Johannes Stuttmann
SummaryHeterodimeric complexes incorporating the lipase-like proteins EDS1 with PAD4 or SAG101 are central hubs in plant innate immunity. EDS1 functions encompass signal relay from TIR domain-containing intracellular NLR-type immune receptors (TNLs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364737971097024a4ebc974bbca0182f
https://doi.org/10.1101/2021.12.15.472806
https://doi.org/10.1101/2021.12.15.472806
Autor:
Giordano Reginato, Sung Sik Lee, Janny Tilma, Vera M. Kissling, Petr Cejka, Ralf Seidel, Gea Cereghetti, Raphael Guerois, Eliana Bianco, Kristina Kasaciunaite, Matthias Peter
The conserved Mre11-Rad50 (MR) complex is crucial for the detection, signaling, end tethering and processing of DNA double-strand breaks (DSBs). While it was known for decades that MR foci formation at DSBs accompanies repair, the underlying molecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::985d2c97de693e99e52d5b7e070088a4
https://doi.org/10.21203/rs.3.rs-811984/v1
https://doi.org/10.21203/rs.3.rs-811984/v1