Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Raphael C Valente"'
Publikováno v:
Noise and Health, Vol 15, Iss 66, Pp 307-314 (2013)
The biological effects of electromagnetic waves are widely studied, especially due to their harmful effects, such as radiation-induced cancer and to their application in diagnosis and therapy. However, the biological effects of sound, another physica
Externí odkaz:
https://doaj.org/article/22b8aa5691204fa894533d7f6587b218
Autor:
Kelli Monteiro da Costa, Raphael C. Valente, Eduardo J. Salustiano, Luciana B. Gentile, Leonardo Freire-de-Lima, Lucia Mendonça-Previato, José O. Previato
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Chagas disease is a neglected disease caused by the protozoan Trypanosoma cruzi and affects 8 million people worldwide. The main chemotherapy is based on benznidazole. The efficacy in the treatment depends on factors such as the parasite strain, whic
Externí odkaz:
https://doaj.org/article/e6465337bc434a92a0ab02fd05702ade
Autor:
Kelli Monteiro da Costa, Raphael C. Valente, Eduardo J. Salustiano, Lucia Mendonça-Previato, José O. Previato, Leonardo Freire-de-Lima
Publikováno v:
Molecules
Molecules, Vol 26, Iss 3510, p 3510 (2021)
Volume 26
Issue 12
Molecules, Vol 26, Iss 3510, p 3510 (2021)
Volume 26
Issue 12
Trypanosoma cruzi is the etiologic agent for Chagas disease, which affects 6–7 million people worldwide. The biological diversity of the parasite reflects on inefficiency of benznidazole, which is a first choice chemotherapy, on chronic patients. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff5ee2a0b9cd5cd32acee62528a26fa7
http://europepmc.org/articles/PMC8227891
http://europepmc.org/articles/PMC8227891
Publikováno v:
Oncology Letters. 12:5275-5280
Ouabain is a glycoside with immunomodulating properties, and recent studies have suggested its use in adjuvant therapy for cancer treatment. Ouabain is known to modulate the immune system in vitro, and previous studies have revealed that ouabain can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd153d0819ec6104a35c07e9c48feaf5
https://doi.org/10.3892/ol.2016.5366
https://doi.org/10.3892/ol.2016.5366
Autor:
Raphael C Valente, Eduardo J. Salustiano, Luciana B. Gentile, José O. Previato, Leonardo Freire-de-Lima, Lucia Mendonça-Previato, Kelli Monteiro da Costa
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Chagas disease is a neglected disease caused by the protozoan Trypanosoma cruzi and affects 8 million people worldwide. The main chemotherapy is based on benznidazole. The efficacy in the treatment depends on factors such as the parasite strain, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ec6b1710ac2387419c9778bc791f4b
http://journal.frontiersin.org/article/10.3389/fmicb.2018.00205/full
http://journal.frontiersin.org/article/10.3389/fmicb.2018.00205/full
Autor:
Kelli Monteiro, da Costa, Raphael C, Valente, Eduardo J, Salustiano, Luciana B, Gentile, Leonardo, Freire-de-Lima, Lucia, Mendonça-Previato, José O, Previato
Publikováno v:
Frontiers in Microbiology
Chagas disease is a neglected disease caused by the protozoan Trypanosoma cruzi and affects 8 million people worldwide. The main chemotherapy is based on benznidazole. The efficacy in the treatment depends on factors such as the parasite strain, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e7683778cea9b202fe0de9dc79386e35
https://pubmed.ncbi.nlm.nih.gov/29491856
https://pubmed.ncbi.nlm.nih.gov/29491856
Autor:
Luiz S. Capella, Raphael C. Valente, Márcia M. M. Oliveira, Marcia A. M. Capella, Luciana T. Nunes-Lima, Fernanda C. M. Cruz, Roberta R. Palmieri, Anibal Gil Lopes
Publikováno v:
Cell Biology and Toxicology. 26:201-213
The cellular actions of ouabain are complex and involve different pathways, depending on the cell type and experimental conditions. Several studies have reported that Madin-Darby canine kidney (MDCK) cellular sensitivity to ouabain is not related to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57f52de36d20c529d62c66fa1cc375ff
https://doi.org/10.1007/s10565-009-9136-8
https://doi.org/10.1007/s10565-009-9136-8
Publikováno v:
Cell Biology and Toxicology. 23:413-420
Vanadium is an environmentally toxic metal with peculiar and sometimes contradictory cellular effects. It is insulin-mimetic, it can either stimulate cell growth or induce cell death, and it has both mutagenic and antineoplastic properties. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe78849ebb05644495fccb5ac05f577c
https://doi.org/10.1007/s10565-007-9003-4
https://doi.org/10.1007/s10565-007-9003-4
Autor:
Marcia A. M. Capella, Clarissa Rodrigues Nascimento, Anibal Gil Lopes, Luiz S. Capella, Raphael C. Valente
Publikováno v:
Cell Biology and Toxicology. 23:421-427
Besides being a (Na(+),K(+))-ATPase inhibitor, high doses of the hormone ouabain have also been reported to modulate both the expression and activity of proteins belonging to the ATP binding cassette family of transporters, such as ABCC7 (CFTR), ABCB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26b870542b496a500b6914ee9e7183e5
https://doi.org/10.1007/s10565-007-9004-3
https://doi.org/10.1007/s10565-007-9004-3
Autor:
Julio A. Mignaco, Vanessa H. Oliveira, Carlos Frederico Leite Fontes, Raphael C. Valente, Saulo Martins Vieira, Otacilio C. Moreira
Publikováno v:
Archives of biochemistry and biophysics. 570
The isoquinoline alkaloid chelerythrine is described as an inhibitor of SERCA. The ATPase inhibition presented two non-competitive components, Ki1 = 1, 2 μM and Ki2 = 26 μM. Conversely, chelerythrine presented a dual effect on the p-nitrophenylphos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::086db7743d30bd4170569ebdca1f9f8a
https://pubmed.ncbi.nlm.nih.gov/25721495
https://pubmed.ncbi.nlm.nih.gov/25721495