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IFN-γ–producing TH1 cells and dysfunctional regulatory T cells contribute to the pathogenesis of Sjögren’s disease

Autor: Wang, Yin-Hu, Li, Wenyi, McDermott, Maxwell, Son, Ga-Yeon, Maiti, George, Zhou, Fang, Tao, Anthony Y., Raphael, Dimitrius, Moreira, Andre L., Shen, Boheng, Vaeth, Martin, Nadorp, Bettina, Chakravarti, Shukti, Lacruz, Rodrigo S., Feske, Stefan

Publikováno v: Science Translational Medicine; December 2024, Vol. 16 Issue: 778

IFN-γ-producing T H 1 cells and dysfunctional regulatory T cells contribute to the pathogenesis of Sjögren's disease.

Autor: Wang YH; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA., Li W; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA., McDermott M; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA., Son GY; Department of Molecular Pathobiology, New York University College of Dentistry, New York, NY 10010, USA., Maiti G; Department of Ophthalmology, New York University Grossman School of Medicine, New York, NY 10016, USA., Zhou F; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA., Tao AY; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA., Raphael D; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA., Moreira AL; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA., Shen B; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA., Vaeth M; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA., Nadorp B; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA.; Division of Precision Medicine, Department of Medicine, New York University Grossman School of Medicine, New York, NY 10016, USA., Chakravarti S; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA.; Department of Ophthalmology, New York University Grossman School of Medicine, New York, NY 10016, USA., Lacruz RS; Department of Molecular Pathobiology, New York University College of Dentistry, New York, NY 10010, USA., Feske S; Department of Pathology, New York University Grossman School of Medicine, New York, NY 10016, USA.

Publikováno v: Science translational medicine [Sci Transl Med] 2024 Dec 18; Vol. 16 (778), pp. eado4856. Date of Electronic Publication: 2024 Dec 18.