Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Raphael, Breuer"'
Autor:
Shulamit B. Wallach-Dayan, Dmytro Petukhov, Ronit Ahdut-HaCohen, Mark Richter-Dayan, Raphael Breuer
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 2177 (2021)
By dint of the aging population and further deepened with the Covid-19 pandemic, lung disease has turned out to be a major cause of worldwide morbidity and mortality. The condition is exacerbated when the immune system further attacks the healthy, ra
Externí odkaz:
https://doaj.org/article/8bea225631c44c848205ece03b7fc2d4
Autor:
Raanan Bulvik, Raphael Breuer, Mona Dvir-Ginzberg, Eli Reich, Neville Berkman, Shulamit B. Wallach-Dayan
Publikováno v:
Biomolecules, Vol 10, Iss 7, p 996 (2020)
In contrast to normal regenerating tissue, resistance to Fas- and FasL-positive T cell-induced apoptosis were detected in myofibroblasts from fibrotic-lungs of humans and mice following bleomycin (BLM) exposure. In this study we show, decreased FLIP
Externí odkaz:
https://doaj.org/article/42c7740c9f064ccfaa78579288e5c382
Publikováno v:
Biomolecules, Vol 10, Iss 7, p 997 (2020)
Regenerative capacity in vital organs is limited by fibrosis propensity. Idiopathic pulmonary fibrosis (IPF), a progressive lung disease linked with aging, is a classic example. In this study, we show that in flow cytometry, immunoblots (IB) and in l
Externí odkaz:
https://doaj.org/article/358926d49e88494b8294466921edf490
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6, p 2228 (2020)
MicroRNAs (miRs) are known to limit gene expression at the post-transcriptional level and have important roles in the pathogenesis of various conditions, including acute lung injury (ALI) and fibrotic diseases such as idiopathic pulmonary fibrosis (I
Externí odkaz:
https://doaj.org/article/f1d3c16638b54cb4aed65b40eeebcac4
Autor:
David Nareznoi, Jenya Konikov-Rozenman, Dmytro Petukhov, Raphael Breuer, Shulamit B. Wallach-Dayan
Publikováno v:
Cells, Vol 9, Iss 2, p 411 (2020)
A prominent feature of obstructed tissue regeneration following injury in general, and fibrotic lung tissue in particular, is fibroblast proliferation and accumulation. The Fas/FasL apoptotic pathway has been shown to be involved in human idiopathic
Externí odkaz:
https://doaj.org/article/afb0567058dd4a4db74a1069f6709606
Autor:
Dmytro Petukhov, Mark Richter-Dayan, Zvi Fridlender, Raphael Breuer, Shulamit B. Wallach-Dayan
Publikováno v:
Cells, Vol 8, Iss 10, p 1211 (2019)
CD44, an adhesion-molecule promoting cell-migration, is shown here to increase in stress conditions following bleomycin-induced apoptosis in alveolar epithelial cells (AECs), a main target of lung injury. In vivo, it inhibits tissue regeneration and
Externí odkaz:
https://doaj.org/article/b99e3a42db8548ecbcefc4073a03a7a1
Publikováno v:
Mediators of Inflammation, Vol 2018 (2018)
Lung fibrosis is characterized by abnormal accumulation of Thy-deficient fibroblasts in the interstitium of the alveolar space. We have previously shown in bleomycin-treated chimeric Thy1-deficient mice with wild-type lymphocytes that Thy1-deficient
Externí odkaz:
https://doaj.org/article/4955cfacb42d4811a77637b4367de1fc
Autor:
Nissim Arish, Pazit Y Cohen, Regina Golan-Gerstl, Zvi Fridlender, Mark Richter Dayan, Philip Zisman, Raphael Breuer, Shulamit B Wallach-Dayan
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126730 (2015)
High doses of bleomycin administered to patients with lymphomas and other tumors lead to significant lung toxicity in general, and to apoptosis of epithelial cells, in particular. Apoptosis of alveolar epithelium is an important step in the pathogene
Externí odkaz:
https://doaj.org/article/564f91e5276a42b3bc512159f78de243
Publikováno v:
Mediators of Inflammation, Vol 2015 (2015)
Lung fibrosis is characterized by abnormal accumulation of fibroblasts in the interstitium of the alveolar space. Two populations of myofibroblasts, distinguished by Thy1 expression, are detected in human and murine lungs. Accumulation of Thy1-negati
Externí odkaz:
https://doaj.org/article/0e4fd347295c43db80524e8cf1432bb1
Autor:
Ronit Ahdut-Hacohen, Shulamit B. Wallach-Dayan, Dmytro Petukhov, Raphael Breuer, Mark Richter-Dayan
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2177, p 2177 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
By dint of the aging population and further deepened with the Covid-19 pandemic, lung disease has turned out to be a major cause of worldwide morbidity and mortality. The condition is exacerbated when the immune system further attacks the healthy, ra