Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Raphaël Gottardo"'
Autor:
Alyssa Sheih, Valentin Voillet, Laïla-Aïcha Hanafi, Hannah A. DeBerg, Masanao Yajima, Reed Hawkins, Vivian Gersuk, Stanley R. Riddell, David G. Maloney, Martin E. Wohlfahrt, Dnyanada Pande, Mark R. Enstrom, Hans-Peter Kiem, Jennifer E. Adair, Raphaël Gottardo, Peter S. Linsley, Cameron J. Turtle
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Understanding factors that impact CAR T cell expansion in the clinic is crucial to improving its therapeutic success. Here the authors document heterogeneity in the clonal dynamics of CAR-T cells by tracking individual clones using the endogenous TCR
Externí odkaz:
https://doaj.org/article/9a5dfb14385d4c6ba59269c0303b6190
Autor:
Sanja Mandaric, Heather Friberg, Xavier Saez-Llorens, Charissa Borja-Tabora, Shibadas Biswal, Ian Escudero, Alice Faccin, Raphael Gottardo, Manja Brose, Nicholas Roubinis, Darlene Fladager, Rodrigo DeAntonio, Julie Anne L. Dimero, Nathali Montenegro, Nicolas Folschweiller, Jeffrey R. Currier, Mayuri Sharma, Vianney Tricou
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-13 (2024)
Abstract As robust cellular responses are important for protection against dengue, this phase 2 study evaluated the kinetics and phenotype of T cell responses induced by TAK-003, a live-attenuated tetravalent dengue vaccine, in 4–16-year-old living
Externí odkaz:
https://doaj.org/article/3b801d6feac84345ad976ff7208a2eac
Autor:
Carla Jaeger, Yun Lo, Elena Fulton, Olivia Waltner, Tamer B. Shabaneh, Colin E. Correnti, Oliver Newsom, Ian A. Engstrom, Sami B. Kanaan, Shruti S. Bhise, Jobelle M.C. Peralta, Raymond Ruff, Jason P. Price, Sylvia M. Stull, Andrew R. Stevens, Valentin Voillet, Vishaka Muhunthan, Fionnuala Morrish, James M. Olson, Raphaël Gottardo, Jay Sarthy, Steven Henikoff, Lucas B. Sullivan, Scott N. Furlan, Stanley R. Riddell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72ef94d2d007888398e97ff450e7c929
https://doi.org/10.2139/ssrn.4402129
https://doi.org/10.2139/ssrn.4402129
Autor:
Mathilde Foglierini, Pauline Nortier, Rachel Schelling, Rahel R. Winiger, Philippe Jacquet, Sijy O’Dell, Davide Demurtas, Maxmillian Mpina, Omar Lweno, Yannick D. Muller, Constantinos Petrovas, Claudia Daubenberger, Matthieu Perreau, Nicole A. Doria-Rose, Raphael Gottardo, Laurent Perez
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Broadly neutralizing antibodies (bNAbs) are promising candidates for the treatment and prevention of HIV-1 infections. Despite their critical importance, automatic detection of HIV-1 bNAbs from immune repertoires is still lacking. Here, we d
Externí odkaz:
https://doaj.org/article/9d102f79207c417eb04c2d3080c48cb2
Autor:
Valentin Voillet, Trisha R. Berger, Kelly M. McKenna, Kelly G. Paulson, Wei Hong Tan, Kimberly S. Smythe, Daniel S. Hunter, William J. Valente, Stephanie Weaver, Jean S. Campbell, Teresa S. Kim, David R. Byrd, Jason H. Bielas, Robert H. Pierce, Aude G. Chapuis, Raphaël Gottardo, Anthony Rongvaux
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 209(3)
Despite recent therapeutic progress, advanced melanoma remains lethal for many patients. The composition of the immune tumor microenvironment (TME) has decisive impacts on therapy response and disease outcome, and high-dimensional analyses of patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15d35e77fe78f95acfd6b197f050d244
https://pubmed.ncbi.nlm.nih.gov/35817516
https://pubmed.ncbi.nlm.nih.gov/35817516
Autor:
Anissa Fries, Fanny Saidoune, François Kuonen, Isabelle Dupanloup, Nadine Fournier, Ana Cristina Guerra de Souza, Muzlifah Haniffa, Feiyang Ma, Johann E. Gudjonsson, Lennart Roesner, Yang Li, Thomas Werfel, Curdin Conrad, Raphael Gottardo, Robert L. Modlin, Jeremy Di Domizio, Michel Gilliet
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Interleukin (IL)-26 is a TH17 cytokine with known antimicrobial and pro-inflammatory functions. However, the precise role of IL-26 in the context of pathogenic TH17 responses is unknown. Here we identify a population of blood TH17 intermedia
Externí odkaz:
https://doaj.org/article/9a6badc4e12148d591a4960524014626
Autor:
Jung Hyun Lee, Justin Daho Lee, Kelly Paulson, Valentin Voillet, Andre Berndt, Candice Church, Kristina Lachance, Song Y. Park, Naomi K. Yamamoto, Elizabeth A. Cromwell, Raphael Gottardo, Aude G. Chapuis, Paul Nghiem
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e23521- (2024)
Approximately 50% of Merkel cell carcinoma (MCC) patients facing this highly aggressive skin cancer initially respond positively to PD-1-based immunotherapy. Nevertheless, the recurrence of MCC post-immunotherapy emphasizes the pressing need for more
Externí odkaz:
https://doaj.org/article/6b3e03a0dc0c42df8e077d2b0c8553fb
Autor:
Philip D Greenberg, Valentin Voillet, Raphael Gottardo, Kristin G Anderson, Breanna M Bates, Madison G Burnett, Susan L Ruskin, Yapeng Su, Magdalia L Suarez Gutierrez
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/02aa15847e644c8caf9301b40b6a786b
Autor:
Joann Diray-Arce, Helen E. R. Miller, Evan Henrich, Bram Gerritsen, Matthew P. Mulè, Slim Fourati, Jeremy Gygi, Thomas Hagan, Lewis Tomalin, Dmitry Rychkov, Dmitri Kazmin, Daniel G. Chawla, Hailong Meng, Patrick Dunn, John Campbell, The Human Immunology Project Consortium (HIPC), Minnie Sarwal, John S. Tsang, Ofer Levy, Bali Pulendran, Rafick Sekaly, Aris Floratos, Raphael Gottardo, Steven H. Kleinstein, Mayte Suárez-Fariñas
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-16 (2022)
Measurement(s) Transcriptomics • Hemagglutination Inhibition Assay • IgG IgM IgA Total Measurement • Virus-neutralizing Antibody • ELISA Technology Type(s) Microarray • RNA sequencing • Hemagglutination Inhibition Assay • ELISA • Micr
Externí odkaz:
https://doaj.org/article/e29b684ada444c44833f7762240235b8
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-17 (2022)
Abstract We consider an increasingly popular study design where single-cell RNA-seq data are collected from multiple individuals and the question of interest is to find genes that are differentially expressed between two groups of individuals. Toward
Externí odkaz:
https://doaj.org/article/a73b1c8eec8a4739ad8b8d5179fa1e70