Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Raphaël Bossart"'
Autor:
Luis Zurkirchen, Sandra Varum, Sonja Giger, Annika Klug, Jessica Häusel, Raphaël Bossart, Martina Zemke, Claudio Cantù, Zeynep Kalender Atak, Nicola Zamboni, Konrad Basler, Lukas Sommer
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
The transcription factor Yin Yang 1 (YY1) plays an important role in human disease, yet little is known about its role in brain development. This study shows that YY1 controls cerebral cortex development by maintaining proliferation and survival of n
Externí odkaz:
https://doaj.org/article/bc26cd50490644df85c84964bd1b920a
Autor:
Lukas Sommer, Mitchell P. Levesque, Yudong Zhang, Ana T. Antunes, Eylul Tuncer, Kwok-Kin Wong, Rodrigo Peña-Hernández, Konrad Basler, Simon M. Schaefer, Phil F. Cheng, Dario Zimmerli, Raquel R. Calçada, Raphaël Bossart, Jessica Haeusel, Daniel Zingg, Julien Debbache, Reinhard Dummer, Raffaella Santoro
Publikováno v:
Cancer cell. 34(1)
Human melanomas frequently harbor amplifications of EZH2. However, the contribution of EZH2 to melanoma formation has remained elusive. Taking advantage of murine melanoma models, we show that EZH2 drives tumorigenesis from benign BrafV600E- or NrasQ
Autor:
Jasper Wouters, Raphaël Bossart, Claudio Cantù, Mitchell P. Levesque, Zeynep Kalender Atak, Luis Zurkirchen, Eylul Tuncer, Konrad Basler, Jessica Häusel, Stein Aerts, Sandra Varum, Dominiek Veen, Lukas Sommer, Daniel Zingg, Nessy John, Arianna Baggiolini, Nicola Zamboni, Elisa Marzorati, Marcel Balz, Reinhard Dummer
Publikováno v:
Cell Stem Cell. 24:637-653.e9
Increasing evidence suggests that cancer cells highjack developmental programs for disease initiation and progression. Melanoma arises from melanocytes that originate during development from neural crest stem cells (NCSCs). Here, we identified the tr