Výsledky vyhledávání - "Raphaël Adda"

An abnormal ProC Global test result is associated with an increased risk of venous thromboembolism independent of test sensitivity for protein C pathway abnormalities

Autor: Raphaël Adda, Patricia Perez, Pierre Toulon, Jocelyn Rapp

Publikováno v: Thrombosis and Haemostasis. 98:228-233

SummaryThe ProC® Global assay is a clotting assay primarily developed to globally evaluate the functionality of the protein C (PC) pathway. It was shown to lack both sensitivity and specificity for PC pathway abnormalities, i.e. factor V Leiden muta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f982f6fbd99a4a60dba013ae20c75a9c
https://doi.org/10.1160/th05-06-0418

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Thrombopoietin Activates Human Platelets and Induces Tyrosine Phosphorylation of p80/85 Cortactin

Autor: Sylviane Levy-Toledano, Raphaël Adda, François Dreyfus, M. Fontenay-Roupie, Guillaume Huret, J. Melle, Jacques Maclouf, Jean-Pierre Loza

Publikováno v: Thrombosis and Haemostasis. 79:195-201

SummaryThe mechanism of human platelet activation by thrombopoietin (TPO) was investigated in vitro. We found that rHuTPO stimulated thromboxane A2 formation and serotonin secretion, despite the absence of shape change and aggregation. Blockade of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152ebfd56de1fddfdf45e58602af3ab2
https://doi.org/10.1055/s-0037-1614239

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Economic Impact of the Introduction of the ProC® Global Assay in the Screening Strategy of Protein C Pathway Abnormalities in Unselected Patients with a History of Venous Thromboembolism

Autor: Pierre Toulon, Patricia Perez, Raphaël Adda

Publikováno v: Thrombosis and Haemostasis. 86:720-721

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7c3660bb570800c3a8bd99379197b98f
https://doi.org/10.1055/s-0037-1616116

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Heparin Cofactor II (HCII) Levels and the Risk of Ischemic Stroke. No Deleterious Role of HCII Deficiency but Potential Protective Role of High Plasma Level

Autor: Mathieu Zuber, Raphaël Adda, Pierre Toulon, Jean-Louis Mas

Publikováno v: Blood. 112:5344-5344

Background: Heparin cofactor II (HCII) is a thrombin inhibitor which activity is dramatically enhanced by heparin and more specifically by dermatan sulfate, another glycosaminoglycan. Its pathophysiological role remains unknown even if cases of HCII

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2ea5dcdd8e76034e946f794d417470a2
https://doi.org/10.1182/blood.v112.11.5344.5344

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