Plasminogen Activator Inhibitor-1 (PAI-1) deficiency predisposes to depression and resistance to treatments

Autor: Hélène Party, Cléo Dujarrier, Marie Hébert, Sophie Lenoir, Sara Martinez de Lizarrondo, Raphaël Delépée, Claudine Fauchon, Marie-Christine Bouton, Pauline Obiang, Olivier Godefroy, Etienne Save, Laurent Lecardeur, Joëlle Chabry, Denis Vivien, Véronique Agin

Publikováno v: Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-12 (2019)

Abstract Major depressive disorder (MDD) is one of the most frequent psychiatric illnesses, leading to reduced quality of life, ability to work and sociability, thus ranking among the major causes of disability and morbidity worldwide. To date, genet

Externí odkaz: https://doaj.org/article/f491f63c017d42d194af67d6b4583770

Blood contamination of the pharmaceutical staff by irinotecan and its two major metabolites inside and outside a compounding unit

Autor: Stéphanie Lagadu, Victoire Béchet, Raphaël Delépée, Frédéric Beau, Fabienne Divanon, H Benoist, François Sichel, Guillaume Saint-Lorant

Publikováno v: Journal of Oncology Pharmacy Practice. 28:777-784

Background Caregivers in healthcare settings are exposed to a risk of antineoplastic drug contamination which can lead to adverse health effects. Biological monitoring is necessary to estimate the actual level of exposure of these workers. This study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5efcddf95b4e6e49779eb107a38c375
https://doi.org/10.1177/10781552211012059

O-123 DNA damage in lymphocytes of female farmers measured using the alkaline comet assay

Autor: Mathilde Boulanger, Séverine Tual, Stéphanie Perrier, Poppy Evenden, Elisa Boutet-Robinet, Yannick Lecluse, Matthieu Meryet-Figuière, Pierre Lebailly, Stefano Bonassi, Anne-Sophie Lacauve, Elodie Niez, Raphaël Delépée, Hervé Perdry

Publikováno v: Oral Presentations.

Introduction Many studies have shown a link between exposure to pesticides and a higher level of DNA damage. However, longitudinal studies are rare and little is known about long term DNA damage and cancer risk in exposed subjects. Objectives i) Quan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b0a1469b5689f8c814020338d94bb189
https://doi.org/10.1136/oem-2021-epi.6

Investigation by mass spectrometry and 32P post-labelling of DNA adducts formation from 1,2-naphthoquinone, an oxydated metabolite of naphthalene

Autor: Isabelle Vaudorne, Victor Babin, Claire Lopez-Piffet, Stéphanie Lagadu, Adeline Clergé, Thomas Cailly, Raphaël Delépée, Sonnich Meier, Jérémie Le Goff

Publikováno v: Chemosphere
Chemosphere, Elsevier, 2021, 263, pp.128079. ⟨10.1016/j.chemosphere.2020.128079⟩
Chemosphere, Elsevier, 2020, ⟨10.1016/j.chemosphere.2020.128079⟩

International audience; Naphthalene is the simplest representative of polycyclic aromatic hydrocarbons (PAHs). It is detected as major pollutant in the different compartments of the environment. This compound is considered by the international agency

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09492083f9be1061fdb30a1ae20330c3
https://hal.archives-ouvertes.fr/hal-03337498

Corrigendum to 'A validated UHPLC-MS/MS method for simultaneous quantification of 9 exocyclic DNA adducts induced by 8 aldehydes' [J. Pharm. Biomed. Anal. 179 (2020) Article Number 1499]

Autor: Mathilde Lechevrel, Zeina Dagher, Stéphanie Lagadu, Raphaël Delépée, Héléna Alamil, Laurence Galanti

Publikováno v: Journal of pharmaceutical and biomedical analysis, Vol. 185, p. 113248 (2020)

The authors regret for not mentioning the correct author contribution [...]

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b53ec926bf70b73c4a57a6804e3897
https://pubmed.ncbi.nlm.nih.gov/31796220