Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Raoul Mansukhani"'
Autor:
Temitayo Shokunbi, Haleema Shakur-Still, Raoul Mansukhani, Antonio Belli, Rizwana Chaudhri, Sabariah Faizah Jamaluddin, Amy Brenner, Lauren Frimley, Rashid Jooma, Ian Roberts
Publikováno v:
Wellcome Open Research, Vol 6 (2024)
Background Each year world-wide about 65 million people sustain a mild traumatic brain injury (mTBI). Fatigue is a common and distressing symptom after mTBI. We examine the effect of tranexamic acid (TXA) on fatigue in patients with mTBI using data f
Externí odkaz:
https://doaj.org/article/b272c6112961459fbff68fbb6102378b
Autor:
Ian Roberts, Oladapo Olayemi, Raoul Mansukhani, Haleema Shakur-Still, Katharine Ker, Luis D. Pacheco, Loïc Sentilhes, Catherine Deneux-Tharaux, George Saade, François-Xavier Ageron, Amy Brenner, Rizwana Chaudhri, Danielle Prowse
Publikováno v:
Gates Open Research, Vol 7 (2023)
Background: Tranexamic acid (TXA) reduces the risk of death and is recommended as a treatment for women with severe postpartum bleeding. There is hope that giving TXA shortly before or immediately after birth could prevent postpartum bleeding. Extend
Externí odkaz:
https://doaj.org/article/1db6e6bc9ace4e1c97397bd36dca8816
Autor:
Amy Brenner, Ian Roberts, Eni Balogun, Folasade Adenike Bello, Rizwana Chaudhri, Charlotte Fleming, Kiran Javaid, Aasia Kayani, Mwansa Ketty Lubeya, Raoul Mansukhani, Oladapo Olayemi, Danielle Prowse, Bellington Vwalika, Haleema Shakur-Still
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-8 (2022)
Abstract Background Postpartum haemorrhage (PPH) is a leading cause of maternal mortality worldwide. Maternal anaemia greatly increases the risk of PPH, and over a third of all pregnant women are anaemic. Because anaemia reduces the oxygen-carrying c
Externí odkaz:
https://doaj.org/article/3d3c8ecbb3664d0cb584240de43aee4e
Autor:
Ian Roberts, Haleema Shakur-Still, Danielle Beaumont, Katharine Ker, Raoul Mansukhani, Monica Arribas
Publikováno v:
BMJ Open, Vol 13, Iss 2 (2023)
Objectives HALT-IT was an international, randomised trial which assessed the effects of tranexamic acid (TXA) in 12 009 patients with gastrointestinal (GI) bleeding. The results found no evidence that TXA reduces death. It is widely accepted that res
Externí odkaz:
https://doaj.org/article/d9461c43fc2d41269f1fd404b578dc31
Autor:
Alison D. Grant, Thobani Ntshiqa, Raoul Mansukhani, Violet Chihota, Kavindhran Velen, Salome Charalambous, Lindiwe Nhlangulela, Thomas R. Hawn, Pholo Maenetje, Gavin Churchyard, Katherine Fielding, Robert Wallis
Publikováno v:
Gates Open Research, Vol 5 (2022)
Background: QuantiFERON-TB-Gold-in-tube (QFT-GIT) is an interferon-gamma release assay (IGRA) used to diagnose latent tuberculosis infection. Limited data exists on performance of QuantiFERON-TB Gold-Plus (QFT-Plus), a next generation of IGRA that in
Externí odkaz:
https://doaj.org/article/f4bb29745d104d7c85c0ba5bafb67e3d
Autor:
Amy Brenner, Antonio Belli, Rizwana Chaudhri, Timothy Coats, Lauren Frimley, Sabariah Faizah Jamaluddin, Rashid Jooma, Raoul Mansukhani, Peter Sandercock, Haleema Shakur-Still, Temitayo Shokunbi, Ian Roberts, On behalf of the CRASH-3 trial collaborators
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-10 (2020)
Abstract Background The CRASH-3 trial hypothesised that timely tranexamic acid (TXA) treatment might reduce deaths from intracranial bleeding after traumatic brain injury (TBI). To explore the mechanism of action of TXA in TBI, we examined the timing
Externí odkaz:
https://doaj.org/article/5e1fb95c036148cfb03f997289f2cd4e
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-8 (2020)
Abstract Background Early treatment with tranexamic acid may reduce deaths after traumatic brain injury (TBI). In mild and moderate TBI, there is a time to treatment interaction, with early treatment being most beneficial. Time to treatment was recor
Externí odkaz:
https://doaj.org/article/b0037ecf046b4bf4901beba59a32c440
Resistance to Mycobacterium tuberculosis infection among highly TB exposed South African gold miners
Autor:
Violet N. Chihota, Thobani Ntshiqa, Pholo Maenetje, Raoul Mansukhani, Kavindhran Velen, Thomas R. Hawn, Robert Wallis, Alison D. Grant, Gavin J. Churchyard, Katherine Fielding
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
Background Despite high exposure to Mycobacterium tuberculosis, a small proportion of South African goldminers resist TB infection. We determined, among long-service gold miners i) the proportion who were TB uninfected and ii) epidemiological factors
Externí odkaz:
https://doaj.org/article/ac91a079a6e042d4a85f5f23b09d3f01
Autor:
Stanislas Grassin-Delyle, Elodie Lamy, Michaela Semeraro, Iléana Runge, Jean-Marc Treluyer, Raoul Mansukhani, Monica Arribas, Ian Roberts, Haleema Shakur-Still
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
We assessed the accuracy of tranexamic acid (TXA) concentrations measured in capillary whole blood using volumetric absorptive micro-sampling (VAMS) devices. Paired venous and VAMS capillary blood samples were collected from 15 healthy volunteers par
Externí odkaz:
https://doaj.org/article/e72f452fe7b94b8c9d5be5c0957f2a55
Autor:
Ian Roberts, Haleema Shakur-Still, Adefemi Afolabi, Adegboyega Akere, Monica Arribas, Emma Austin, Kiran Bal, Nuha Bazeer, Danielle Beaumont, Amy Brenner, Laura Carrington, Rizwana Chaudhri, Timothy Coats, Ian Gilmore, Kenneth Halligan, Irshad Hussain, Vipul Jairath, Kiran Javaid, Aasia Kayani, Ton Lisman, Raoul Mansukhani, Alec Miners, Muttiullah Mutti, Muhammad Arif Nadeem, Richard Pollok, Danielle Prowse, Jonathan Simmons, Simon Stanworth, Andrew Veitch, Jack Williams
Publikováno v:
Health Technology Assessment, Vol 25, Iss 58 (2021)
Background: Tranexamic acid reduces blood loss in surgery and the risk of death in trauma patients. Meta-analyses of small trials suggest that tranexamic acid decreases the number of deaths from gastrointestinal bleeding, but these meta-analyses are
Externí odkaz:
https://doaj.org/article/cbd5f7e4c4584e339cd0438d7a52635c