Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Raoul J. de Groot"'
Autor:
Chunyan Wang, Emma L. Hesketh, Tatiana M. Shamorkina, Wentao Li, Peter J. Franken, Dubravka Drabek, Rien van Haperen, Sarah Townend, Frank J. M. van Kuppeveld, Frank Grosveld, Neil A. Ranson, Joost Snijder, Raoul J. de Groot, Daniel L. Hurdiss, Berend-Jan Bosch
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Human coronavirus OC43 causes respiratory disease and is maintained in the human population through recurring infections. Here, by extensive structural analyses, the authors provide insights into the binding sites and breadth of neutralizing antibodi
Externí odkaz:
https://doaj.org/article/a254f75862064c1d9048eaf549552960
Autor:
Daniel L. Hurdiss, Ieva Drulyte, Yifei Lang, Tatiana M. Shamorkina, Matti F. Pronker, Frank J. M. van Kuppeveld, Joost Snijder, Raoul J. de Groot
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Human coronavirus-HKU1 contains two surface projections called spike and haemagglutinin-esterase (HE), with the latter acting as a receptor-destroying enzyme. Here, the authors use cryo-EM and mass spectrometry to characterise the small, heavily glyc
Externí odkaz:
https://doaj.org/article/e39f8123487b43869c78601f60414a16
Autor:
Martijn A. Langereis, Mark J.G. Bakkers, Lingquan Deng, Vered Padler-Karavani, Stephin J. Vervoort, Ruben J.G. Hulswit, Arno L.W. van Vliet, Gerrit J. Gerwig, Stefanie A.H. de Poot, Willemijn Boot, Anne Marie van Ederen, Balthasar A. Heesters, Chris M. van der Loos, Frank J.M. van Kuppeveld, Hai Yu, Eric G. Huizinga, Xi Chen, Ajit Varki, Johannis P. Kamerling, Raoul J. de Groot
Publikováno v:
Cell Reports, Vol 11, Iss 12, Pp 1966-1978 (2015)
Sialic acids (Sias), 9-carbon-backbone sugars, are among the most complex and versatile molecules of life. As terminal residues of glycans on proteins and lipids, Sias are key elements of glycotopes of both cellular and microbial lectins and thus act
Externí odkaz:
https://doaj.org/article/c810e7e811be4ad3b07b1a33d7f7d1fb
Autor:
Martijn A. Langereis, Qinghong Zeng, Balthasar A. Heesters, Eric G. Huizinga, Raoul J. de Groot
Publikováno v:
PLoS Pathogens, Vol 8, Iss 2 (2012)
Externí odkaz:
https://doaj.org/article/d4976cdcca5140108a918f2d76c815f2
Autor:
Chiara Aloise, Jelle G Schipper, Arno van Vliet, Judith Oymans, Tim Donselaar, Daniel L Hurdiss, Raoul J de Groot, Frank J M van Kuppeveld
Publikováno v:
PLoS Pathogens, Vol 19, Iss 8, p e1011582 (2023)
The nucleocapsid protein N of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enwraps and condenses the viral genome for packaging but is also an antagonist of the innate antiviral defense. It suppresses the integrated stress response (I
Externí odkaz:
https://doaj.org/article/f7de8a47b87c4e9e88b06cd5bac75e80
Autor:
Matti F. Pronker, Robert Creutznacher, Ieva Drulyte, Ruben J.G. Hulswit, Zeshi Li, Frank J.M. van Kuppeveld, Joost Snijder, Yifei Lang, Berend-Jan Bosch, Geert-Jan Boons, Martin Frank, Raoul J. de Groot, Daniel L. Hurdiss
Coronavirus (CoV) spikes mediate receptor binding and membrane fusion, making them prime targets for neutralising antibodies. In the cases of SARS-CoV, SARS-CoV-2, and MERS-CoV, spikes transition freely between open and closed conformations to balanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86593eb6f8d9487226a1b5917189f47f
https://doi.org/10.1101/2023.04.20.536837
https://doi.org/10.1101/2023.04.20.536837
Publikováno v:
ACS Infectious Diseases. 8:1041-1050
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28c32af97b4cf89e4f98f930f8c82527
https://doi.org/10.1021/acsinfecdis.2c00046
https://doi.org/10.1021/acsinfecdis.2c00046
Autor:
Chiara Aloise, Jelle G. Schipper, Arno van Vliet, Judith Oymans, Tim Donselaar, Daniel L. Hurdiss, Raoul J. de Groot, Frank J.M. van Kuppeveld
The nucleocapsid protein N of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) enwraps and condenses the viral genome for packaging but is also an antagonist of the innate antiviral defense. It suppresses the integrated stress response (I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57ea215ede9f248b299c8dee806e9aa0
https://doi.org/10.1101/2022.09.02.506332
https://doi.org/10.1101/2022.09.02.506332
Autor:
Gerrit J. Gerwig, Johannis P. Kamerling, Arno L. W. van Vliet, Reinhard Vlasak, Raoul J. de Groot, Arjen Lissenberg, Peter Briza, Saskia L. Smits
Publikováno v:
The Journal of Biological Chemistry
Many viruses achieve reversible attachment to sialic acid (Sia) by encoding envelope glycoproteins with receptor-binding and receptor-destroying activities. Toroviruses and group 2 coronaviruses bind to O-acetylated Sias, presumably via their spike p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ce0257e476f4a8b2866575b68b0dd8
http://europepmc.org/articles/PMC8062793
http://europepmc.org/articles/PMC8062793
Publikováno v:
ACS infectious diseases. 8(5)
A panel of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::71dee0d2f90be4bd1cb2d42c8cea1bd6
https://pubmed.ncbi.nlm.nih.gov/35416033
https://pubmed.ncbi.nlm.nih.gov/35416033