Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Raoní Scheibler Rambo"'
Autor:
Alexia de Matos Czeczot, Candida Deves Roth, Rodrigo Gay Ducati, Kenia Pissinate, Raoní Scheibler Rambo, Luís Fernando Saraiva Macedo Timmers, Bruno Lopes Abbadi, Fernanda Souza Macchi, Víctor Zajaczkowski Pestana, Luiz Augusto Basso, Pablo Machado, Cristiano Valim Bizarro
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 847-855 (2021)
The dihydroneopterin aldolase (DHNA, EC 4.1.2.25) activity of FolB protein is required for the conversion of 7,8-dihydroneopterin (DHNP) to 6-hydroxymethyl-7,8-dihydropterin (HP) and glycolaldehyde (GA) in the folate pathway. FolB protein from Mycoba
Externí odkaz:
https://doaj.org/article/adfbb94f578e4e9eae055faaa791c0f4
Autor:
Mario Alejandro Duque-Villegas, Bruno Lopes Abbadi, Paulo Ricardo Romero, Letícia Beatriz Matter, Luiza Galina, Pedro Ferrari Dalberto, Valnês da Silva Rodrigues-Junior, Rodrigo Gay Ducati, Candida Deves Roth, Raoní Scheibler Rambo, Eduardo Vieira de Souza, Marcia Alberton Perello, Héctor Ricardo Morbidoni, Pablo Machado, Luiz Augusto Basso, Cristiano Valim Bizarro
Publikováno v:
Microbiology Spectrum, Vol 9, Iss 3 (2021)
ABSTRACT The epidemiological importance of mycobacterial species is indisputable, and the necessity to find new molecules that can inhibit their growth is urgent. The shikimate pathway, required for the synthesis of important bacterial metabolites, r
Externí odkaz:
https://doaj.org/article/7923956a598648dcb7e2d9179f3e718c
Autor:
Ana Flávia Borsoi, Josiane Delgado Paz, Kenia Pissinate, Raoní Scheibler Rambo, Víctor Zajaczkowski Pestana, Cristiano Valim Bizarro, Luiz Augusto Basso, Pablo Machado
Publikováno v:
Molecules, Vol 26, Iss 5, p 1215 (2021)
Tuberculosis (TB) has been described as a global health crisis since the second half of the 1990s. Mycobacterium tuberculosis (Mtb), the etiologic agent of TB in humans, is a very successful pathogen, being the main cause of death in the population a
Externí odkaz:
https://doaj.org/article/c035c06d4887429eb7100e70fcad1573
Autor:
Josiane Delgado Paz, Nathalia Denise de Moura Sperotto, Alessandro Silva Ramos, Kenia Pissinate, Valnês da Silva Rodrigues Junior, Bruno Lopes Abbadi, Ana Flávia Borsoi, Raoní Scheibler Rambo, Ana Carolina Corso Minotto, Adilio da Silva Dadda, Luiza Galina, Fernanda Souza Macchi Hopf, Mauro Neves Muniz, Leonardo Kras Borges Martinelli, Candida Deves Roth, Rodrigo Braccini Madeira Silva, Marcia Alberton Perelló, Alexia de Matos Czeczot, Christiano Ev Neves, Lovaine Silva Duarte, Mariana Leyser, Sílvia Dias de Oliveira, Cristiano Valim Bizarro, Pablo Machado, Luiz Augusto Basso
Publikováno v:
European Journal of Medicinal Chemistry. 245:114908
Herein a series of 4-aminoquinolines were synthesized in an attempt to optimize and study the structural features related to LABIO-17 biological activity, a Mycobacterium tuberculosis NADH-dependent enoyl-acyl carrier protein reductase (MtInhA) inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4ddf8b5254d536a5b68e70bfefd03c7
https://doi.org/10.1016/j.ejmech.2022.114908
https://doi.org/10.1016/j.ejmech.2022.114908